Risk/Reward is the only thing I take into account when it comes to buying stocks. The "cause" doesn't factor into it at all. If their business plan was giving people ALS instead of curing it I would buy it if I thought I was going to make money. Check out BION if you're looking for a pinky that can offer a huge return. Risky as all pinksheets are but I think they're going to make it eventually...good cause too
http://www.bionitrogen.com/