View Full Version : Neuroimaging research suggests that even mild cases of COVID-19 leave a lasting mark on the brain
RandomGuy
10-08-2021, 08:20 AM
:lol "natural immunity" crowd
If you don't vaccinate because of hyped up fears of some vague fear of long term side effects of the vaccine, you are going to expose yourself to the long term effects of the disease.
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With more than 18 months of the pandemic in the rearview mirror, researchers have been steadily gathering new and important insights into the effects of COVID-19 on the body and brain. These findings are raising concerns about the long-term impacts that the coronavirus might have on biological processes such as aging.
As a cognitive neuroscientist, my past research has focused on understanding how normal brain changes related to aging affect people’s ability to think and move – particularly in middle age and beyond. But as more evidence came in showing that COVID-19 could affect the body and brain for months or longer following infection, my research team became interested in exploring how it might also impact the natural process of aging.
In that study, researchers relied on an existing database called the UK Biobank, which contains brain imaging data from over 45,000 people in the U.K. going back to 2014. This means – crucially – that there was baseline data and brain imaging of all of those people from before the pandemic.
The research team analyzed the brain imaging data and then brought back those who had been diagnosed with COVID-19 for additional brain scans. They compared people who had experienced COVID-19 to participants who had not, carefully matching the groups based on age, sex, baseline test date and study location, as well as common risk factors for disease, such as health variables and socioeconomic status.
The team found marked differences in gray matter – which is made up of the cell bodies of neurons that process information in the brain – between those who had been infected with COVID-19 and those who had not. Specifically, the thickness of the gray matter tissue in brain regions known as the frontal and temporal lobes was reduced in the COVID-19 group, differing from the typical patterns seen in the group that hadn’t experienced COVID-19.
In the general population, it is normal to see some change in gray matter volume or thickness over time as people age, but the changes were larger than normal in those who had been infected with COVID-19.
Interestingly, when the researchers separated the individuals who had severe enough illness to require hospitalization, the results were the same as for those who had experienced milder COVID-19. That is, people who had been infected with COVID-19 showed a loss of brain volume even when the disease was not severe enough to require hospitalization.
Finally, researchers also investigated changes in performance on cognitive tasks and found that those who had contracted COVID-19 were slower in processing information, relative to those who had not.
While we have to be careful interpreting these findings as they await formal peer review, the large sample, pre- and post-illness data in the same people and careful matching with people who had not had COVID-19 have made this preliminary work particularly valuable.
(rest of article here)
https://www.psypost.org/2021/10/neuroimaging-research-suggests-that-even-mild-cases-of-covid-19-leave-a-lasting-mark-on-the-brain-61938
hater
10-08-2021, 08:40 AM
1.hour of fox, cnn or msnbc are probably more harmful to the brain than 2.covid infections.
pgardn
10-08-2021, 08:50 AM
1.hour of fox, cnn or msnbc are probably more harmful to the brain than 2.covid infections.
holy shit, we agree... sort of.
hater
10-08-2021, 08:52 AM
holy shit, we agree... sort of.
:tu
"But if you're vaccinated and get COVID anyhow, the effects are more mild"
:lol
Thread
10-08-2021, 09:33 AM
Just wait till this thing is (over)...then we'll find out how fucked up the one's who got it and the one's who got shot really are.
ChumpDumper
10-08-2021, 09:33 AM
:lol DMC puts straw man in quotes.
hater
10-08-2021, 09:34 AM
"But if you're vaccinated and get COVID anyhow, the effects are more mild"
:lol
:lol
RandomGuy
10-08-2021, 10:16 AM
1.hour of fox, cnn or msnbc are probably more harmful to the brain than 2.covid infections.
Wow. You may have struck a chord here. Agree.
Just wait till this thing is (over)...then we'll find out how fucked up the one's who got it and the one's who got shot really are.
Maybe, but the ones who didn't get shot will be unemployed.
Thread
10-08-2021, 10:23 AM
Maybe, but the ones who didn't get shot will be unemployed.
Yep, the unshot will not be permitted back into "the circle of trust."
hater
10-08-2021, 10:41 AM
Wow. You may have struck a chord here. Agree.
:tu
hater
10-08-2021, 10:42 AM
Yep, the unshot will not be permitted back into "the circle of trust."
Antisocial psychopaths
They should be locked inside the nation inner cities and barbed wire all around.
Think escape from LA/NY
SnakeBoy
10-08-2021, 12:08 PM
On the nightly news, Gutfeld thoroughly debunked this story.
DarrinS
10-08-2021, 05:11 PM
:lol "natural immunity" crowd
^ Natural immunity denier
I think he's referring wrongly to herd immunity crowd or people who think they are immune even if they never got the virus.
rogcl1
10-08-2021, 10:07 PM
1.hour of fox, cnn or msnbc are probably more harmful to the brain than 2.covid infections.
Yes ,on that we agree.
RandomGuy
10-09-2021, 08:42 AM
^ Natural immunity denier
:lol
Sour grapes DS.
Natural immunity exists. But getting to it, especially without vaccination appears to expose you to risk of cognitive loss.
RandomGuy
10-09-2021, 08:43 AM
I think he's referring wrongly to herd immunity crowd or people who think they are immune even if they never got the virus.
I am referring to the people who think natural immunity is somehow less harmful than the vaccination, because its "natural".
.
RandomGuy
10-09-2021, 09:10 AM
On the nightly news, Gutfeld thoroughly debunked this story.
:lol
Winehole23
10-09-2021, 09:16 AM
https://pbs.twimg.com/media/FBQcKfWWYAkrnHv?format=jpg&name=900x900
I am referring to the people who think natural immunity is somehow less harmful than the vaccination, because its "natural".
.
Holy shit :lol
Do you think people with "natural immunity" chose to get COVID? Their concern is that they already have immunity and should not be required to vaccinate.
:lol
Sour grapes DS.
Natural immunity exists. But getting to it, especially without vaccination appears to expose you to risk of cognitive loss.
Thread title "even mild cases"
:lmao
Thread
10-09-2021, 10:53 AM
https://pbs.twimg.com/media/FBQcKfWWYAkrnHv?format=jpg&name=900x900
I suppose having those MASH units mandated like with President Trump is no longer a mandated option.
I suppose having that hospital ship taken out of mothballs and mandated to set sail south out of New York is no longer a mandated option.
Why? Simple:::money was nary problem then. Now, money is a problem.
COVID has outlived it's shelf life.
tee, hee.
The U.S. spends lavishly on healthcare yet can’t answer basic questions about Covid-19. Some of the best research has come from Israel. American public health agencies should be producing data on breakthrough infections, boosters and natural immunity. But the Centers for Disease Control and Prevention has failed to provide the information needed to inform a sound Covid strategy.
Israel began its vaccine rollout with Pfizer in December, only days after the U.S. But Israel kept good data, reported them out frequently and quickly, and used them to track subsequent Covid infections. When the White House announced its plan to recommend a booster shot for all Americans, it cited Israeli data. The World Health Organization and others criticized the plan, calling the evidence insufficient, and in what seemed like a coordinated protest, two top scientists at the Food and Drug Administration abruptly resigned.
The Biden administration recently got the supporting data it needed to justify its booster plan. But not from the CDC. Another Israeli study showed that a booster resulted in a 10-fold reduction in severe Covid illness in people over 60. The results were published mere weeks after the study’s completion, not months later as often happens in the U.S.
“There’s no doubt,” Anthony Fauci said of the findings in a press briefing, “from the dramatic data from the Israeli study that the boosts that are being now done there and contemplated here support very strongly the rationale for such an approach.” The FDA, trying to evaluate the question of boosters, scrambled to obtain the raw data from Israel.
The bigger question is: Why didn’t the CDC produce the research? The agency has 21,000 employees and a $15 billion annual budget. It has data on more than 40 million Americans who have tested positive for Covid and 200 million who have been vaccinated. The data include the vaccine type, dosing schedule and vaccination date. Calculating the rate of U.S. breakthrough infections and subsequent hospitalizations and deaths isn’t the Manhattan Project. It’s Epidemiology 101.
The CDC’s failure to report meaningful data has left policy makers flying blind. In the absence of good data to answer the basic questions Americans have been asking, political opinions have filled the vacuum. Strong data might have prevented much of the polarization over Covid.
Sound data from the CDC has been especially lacking on natural immunity from prior Covid infection. On Aug. 25, Israel published the most powerful and scientifically rigorous study on the subject to date. In a sample of more than 700,000 people, natural immunity was 27 times more effective than vaccinated immunity in preventing symptomatic infections.
Despite this evidence, U.S. public health officials continue to dismiss natural immunity, insisting that those who have recovered from Covid must still get the vaccine. Policy makers and public health leaders, and the media voices that parrot them, are inexplicably sticking to their original hypothesis that natural immunity is fleeting, even as at least 15 studies show it lasts.
Meanwhile, employers fire workers with natural immunity who won’t get vaccinated. Schools disenroll students who won’t comply.
The CDC did put out a study on natural immunity last month, forcefully concluding that vaccinated immunity was 2.3 times better than natural immunity. The CDC used these results to justify telling those with natural immunity to get vaccinated.
But the rate of infection in each group was less than 0.01%, meaning infections were exceedingly rare in the short two-month time period the agency chose to study. This is odd, given there are more than a year of data available. Moreover, despite having data on all 50 states, the CDC only reported data from Kentucky. Was Kentucky the only state that produced the desired result? Why else exclude the same data from the other 49 states?
Some public health officials are afraid to acknowledge natural immunity because they fear some will choose infection over vaccination. But leaders can encourage all Americans who aren’t immune to get vaccinated and be transparent with the data at the same time.
The CDC shouldn’t fish for data to support outdated hypotheses. Heeding the robust Israeli data on natural immunity could help restore the agency’s credibility and even help vaccination efforts.
Israel also contributed a brilliant study on vaccinating children. Researchers found that one dose of the Pfizer vaccine, instead of the normal two, was 100% effective in children ages 12 to 15. Such a finding could have significant implications for achieving broad immunity in adolescents while reducing the risk of heart complications, which have been clustered around the second dose.
These are the studies U.S. public health agencies should be doing but aren’t. By any metric, the CDC has failed in its primary task of preparing the country for a pandemic and telling us how to reduce harm from the novel Covid pathogen.
Dr. Makary is a professor at the Johns Hopkins University School of Medicine, and the author of “The Price We Pay: What Broke American Health Care—And How To Fix It.”
https://www.wsj.com/articles/covid-19-coronavirus-breakthrough-vaccine-natural-immunity-cdc-fauci-biden-failure-11631548306
Trainwreck2100
10-09-2021, 11:00 AM
The U.S. spends lavishly on healthcare yet can’t answer basic questions about Covid-19. Some of the best research has come from Israel. American public health agencies should be producing data on breakthrough infections, boosters and natural immunity. But the Centers for Disease Control and Prevention has failed to provide the information needed to inform a sound Covid strategy.
Israel began its vaccine rollout with Pfizer in December, only days after the U.S. But Israel kept good data, reported them out frequently and quickly, and used them to track subsequent Covid infections. When the White House announced its plan to recommend a booster shot for all Americans, it cited Israeli data. The World Health Organization and others criticized the plan, calling the evidence insufficient, and in what seemed like a coordinated protest, two top scientists at the Food and Drug Administration abruptly resigned.
The Biden administration recently got the supporting data it needed to justify its booster plan. But not from the CDC. Another Israeli study showed that a booster resulted in a 10-fold reduction in severe Covid illness in people over 60. The results were published mere weeks after the study’s completion, not months later as often happens in the U.S.
“There’s no doubt,” Anthony Fauci said of the findings in a press briefing, “from the dramatic data from the Israeli study that the boosts that are being now done there and contemplated here support very strongly the rationale for such an approach.” The FDA, trying to evaluate the question of boosters, scrambled to obtain the raw data from Israel.
The bigger question is: Why didn’t the CDC produce the research? The agency has 21,000 employees and a $15 billion annual budget. It has data on more than 40 million Americans who have tested positive for Covid and 200 million who have been vaccinated. The data include the vaccine type, dosing schedule and vaccination date. Calculating the rate of U.S. breakthrough infections and subsequent hospitalizations and deaths isn’t the Manhattan Project. It’s Epidemiology 101.
The CDC’s failure to report meaningful data has left policy makers flying blind. In the absence of good data to answer the basic questions Americans have been asking, political opinions have filled the vacuum. Strong data might have prevented much of the polarization over Covid.
Sound data from the CDC has been especially lacking on natural immunity from prior Covid infection. On Aug. 25, Israel published the most powerful and scientifically rigorous study on the subject to date. In a sample of more than 700,000 people, natural immunity was 27 times more effective than vaccinated immunity in preventing symptomatic infections.
Despite this evidence, U.S. public health officials continue to dismiss natural immunity, insisting that those who have recovered from Covid must still get the vaccine. Policy makers and public health leaders, and the media voices that parrot them, are inexplicably sticking to their original hypothesis that natural immunity is fleeting, even as at least 15 studies show it lasts.
Meanwhile, employers fire workers with natural immunity who won’t get vaccinated. Schools disenroll students who won’t comply.
The CDC did put out a study on natural immunity last month, forcefully concluding that vaccinated immunity was 2.3 times better than natural immunity. The CDC used these results to justify telling those with natural immunity to get vaccinated.
But the rate of infection in each group was less than 0.01%, meaning infections were exceedingly rare in the short two-month time period the agency chose to study. This is odd, given there are more than a year of data available. Moreover, despite having data on all 50 states, the CDC only reported data from Kentucky. Was Kentucky the only state that produced the desired result? Why else exclude the same data from the other 49 states?
Some public health officials are afraid to acknowledge natural immunity because they fear some will choose infection over vaccination. But leaders can encourage all Americans who aren’t immune to get vaccinated and be transparent with the data at the same time.
The CDC shouldn’t fish for data to support outdated hypotheses. Heeding the robust Israeli data on natural immunity could help restore the agency’s credibility and even help vaccination efforts.
Israel also contributed a brilliant study on vaccinating children. Researchers found that one dose of the Pfizer vaccine, instead of the normal two, was 100% effective in children ages 12 to 15. Such a finding could have significant implications for achieving broad immunity in adolescents while reducing the risk of heart complications, which have been clustered around the second dose.
These are the studies U.S. public health agencies should be doing but aren’t. By any metric, the CDC has failed in its primary task of preparing the country for a pandemic and telling us how to reduce harm from the novel Covid pathogen.
Dr. Makary is a professor at the Johns Hopkins University School of Medicine, and the author of “The Price We Pay: What Broke American Health Care—And How To Fix It.”
https://www.wsj.com/articles/covid-19-coronavirus-breakthrough-vaccine-natural-immunity-cdc-fauci-biden-failure-11631548306.
Socialized medicine
.
Socialized medicine
Border wall
boutons_deux
10-09-2021, 11:49 AM
.
Socialized medicine
FDA/CDC has been under Trump/Repug sycophants' degradation for 3 years when the pandemic hit.
Repug states were LYING about cause of death in 2020, reporting "pneumonia" or "blank" cause of death on coroner reports to Wash DC.
Repugs and their cult base have made America is ungovernable.
Thread
10-09-2021, 12:16 PM
FDA/CDC has been under Trump/Repug sycophants' degradation for 3 years when the pandemic hit.
Repug states were LYING about cause of death in 2020, reporting "pneumonia" or "blank" cause of death on coroner reports to Wash DC.
Repugs and their cult base have made America is ungovernable.
...not only good, but excellent. That's precisely what you did to President Trump for 4 years. Once & again, you can dish it, bouts, but you cannot take it.
ChumpDumper
10-09-2021, 12:20 PM
Strong data might have prevented much of the polarization over Covid.
No chance in hell.
ChumpDumper
10-09-2021, 12:21 PM
Border wallNo one is stopping you from building it.
Chop chop.
Winehole23
10-09-2021, 04:10 PM
.
Socialized medicineamazing what fully-funded, public-facing, public-health oriented public healthcare can do.
must’ve been one hell of a tip jar.
baseline bum
10-09-2021, 05:22 PM
Holy shit :lol
Do you think people with "natural immunity" chose to get COVID? Their concern is that they already have immunity and should not be required to vaccinate.
If they got it after refusing vaccination, yeah they chose to get COVID.
DarrinS
10-09-2021, 06:03 PM
If they got it after refusing vaccination, yeah they chose to get COVID.
Millions of people got it pre-vaccine.
If they got it after refusing vaccination, yeah they chose to get COVID.
It doesn't delineate it that way. It simply says natural immunity (i.e. already have COVID) vs vaccination alone. The CDC plays semantical games with it, saying something like "Vaccine proves more resistance to COVID than does natural immunity" then when you read the article it's saying if you already had COVID then got the vaccine, you have more immunity than just natural immunity. Once again the CDC is playing politics and issuing guidance based on political motives instead of following the science.
New CDC Study: Vaccination Offers Higher Protection than Previous COVID-19 Infection (this would make you think it's a study of those who are vaccinated who never had COVID vs those who had COVID and were never vaccinated. But no, there's more)
In today’s MMWR, a study of COVID-19 infections in Kentucky among people who were previously infected with SAR-CoV-2 shows that unvaccinated individuals are more than twice as likely to be reinfected with COVID-19 than those who were fully vaccinated after initially contracting the virus. These data further indicate that COVID-19 vaccines offer better protection than natural immunity alone and that vaccines, even after prior infection, help prevent reinfections.
"but they mean well"
Also.. lol "Kentucky".,
I think the WSJ does a good job calling that cherry picking out.
amazing what fully-funded, public-facing, public-health oriented public healthcare can do.
must’ve been one hell of a tip jar.
That's behind a border wall with a very low immigration level in a country that's financially buoyed by American tax dollars.
Would you like a government like Israel has?
Yes or no?
Winehole23
10-10-2021, 12:24 AM
That's behind a border wall with a very low immigration level in a country that's financially buoyed by American tax dollars.
Would you like a government like Israel has?
Yes or no?I’d like healthcare like they have.
I’d like healthcare like they have.
I didn't ask you that. Do you want their government so that you can also have their healthcare?
Yes or no?
Why can't we be more like Israel?
If your neighbor drives a new Audi A6 and lives in a trailer home, would you like to drive an Audi A6? Are you willing to live in a trailer home to do so?
Surely you're not that naive
Winehole23
10-10-2021, 10:02 AM
I didn't ask you that. Do you want their government so that you can also have their healthcare?
Yes or no?
Why can't we be more like Israel?
If your neighbor drives a new Audi A6 and lives in a trailer home, would you like to drive an Audi A6? Are you willing to live in a trailer home to do so?
Surely you're not that naiveI reject your stipulations. We can have single payer healthcare without resembling Israel.
Tbh, all we'd have to do is pass enabling legislation and fund it. Lowering Medicare eligibility to age zero would be a good start.
Thread
10-10-2021, 10:06 AM
I reject your stipulations. We can have single payer healthcare without resembling Israel.
TBF, all we'd have to do is pass enabling legislation and fund it.
Maybe at 3.2 trillion, but Manchin put the stopper in the bottle on that amount. 2.2 trillion won't brook it.
I reject your stipulations. We can have single payer healthcare without resembling Israel.
Tbh, all we'd have to do is pass enabling legislation and fund it. Lowering Medicare eligibility to age zero would be a good start.
But you didn't open the can of worms based on socialized medicine, but on how Israel's system worked for them. You cannot ignore how you got there. I mean, just look at all the scientific breakthroughs the Nazis had! Justifies their government, right? Why can't the US test people until they die to see what extremes the human body can endure?
Winehole23
10-10-2021, 06:34 PM
But you didn't open the can of worms based on socialized medicine, but on how Israel's system worked for them. You cannot ignore how you got there. I mean, just look at all the scientific breakthroughs the Nazis had! Justifies their government, right? Why can't the US test people until they die to see what extremes the human body can endure?To become Israel, we would already have to have been Israel, true.
That wasn’t what I was talking about though. It’s curious how you prefer to reorient the discussion to the conversation you’re having with yourself, in your head. What you take for logical necessities are often idiosyncratic leaps based on misunderstandings or distortions of what others have said.
To become Israel, we would already have to have been Israel, true.
That wasn’t what I was talking about though. It’s curious how you prefer to reorient the discussion to the conversation you’re having with yourself, in your head. What you take for logical necessities are often idiosyncratic leaps based on misunderstandings or distortions of what others have said.
:lol Your socialized medicine epiphany didn't go well. You're trying to recover.
pgardn
10-10-2021, 08:05 PM
The U.S. spends lavishly on healthcare yet can’t answer basic questions about Covid-19.
https://www.wsj.com/articles/covid-19-coronavirus-breakthrough-vaccine-natural-immunity-cdc-fauci-biden-failure-11631548306
This doctor claims we spend lavishly on health care and then says we cant answer basic questions about Covid.
Then claims the CDC and other government agencies are playing games?
Again the hypocrisy is amazing. MOST of the Massive amounts of money spent on health care DOES NOT GO to research on Covid.
Always the hypocrisy. He brings out some good points after he has done the same thing himself. And basic questions on something this new are still very difficult. There are some basic molecular questions that are indeed still difficult because we dont know how different immune systems react. Part of this is the vast difference in immune responses in the DIVERSE POPULATIONS the virus infects. This point is consistently left out.
pgardn
10-10-2021, 08:14 PM
Millions of people got it pre-vaccine.
Yep.
And at that time it was the sniffles until it was'nt.
And even then, fear the needle!
Winehole23
10-10-2021, 08:21 PM
:lol Your socialized medicine epiphany didn't go well. You're trying to recover.Pretty sure if it ever goes down here it’ll involve lowering the age of Medicare eligibility, either progressively or instantly.
Ef-man
10-10-2021, 08:54 PM
No one is stopping you from building it.
Chop chop.
Thought Mexico paid for the wall because we do not want socialist border security, amirite?
pgardn
10-10-2021, 09:08 PM
Thought Mexico paid for the wall because we do not want socialist border security, amirite?
Its the Mexicans from all the wanna be Cowboy states and their governors.
Those are the Mexicans. Abbott and his Wyoming benefactor are also Mexicans.
Pretty sure if it ever goes down here it’ll involve lowering the age of Medicare eligibility, either progressively or instantly.
It won't go down here. There's too much money with too many decision makers that's based on it staying how it is.
Its the Mexicans from all the wanna be Cowboy states and their governors.
Those are the Mexicans. Abbott and his Wyoming benefactor are also Mexicans.
:lol There was one guy with a cowboy hat on. No one else in the photo was dressed like a cowboy.
:lol you thought the general was guarding the group
Thought Mexico paid for the wall because we do not want socialist border security, amirite?
"amirite guise? eh? eh?" -Reck
spurraider21
10-10-2021, 10:46 PM
Millions of people got it pre-vaccine.
they could have taken zinc though
Winehole23
10-10-2021, 10:47 PM
It won't go down here. There's too much money with too many decision makers that's based on it staying how it is.Prediction is a fool’s game.
Pretty sure if it ever goes down here it’ll involve lowering the age of Medicare eligibility, either progressively or instantly.
Prediction is a fool’s game.
Ef-man
10-10-2021, 11:04 PM
"amirite guise? eh? eh?" -Reck
Prediction is a fool’s game.
ChumpDumper
10-11-2021, 09:38 AM
:lol Your socialized medicine epiphany didn't go well. You're trying to recover.
You'll sign up for socialized medicine the second you're eligible.
I clicked on the quote notification and got this
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