Repug drug companies control FDA to slow generics approval

[boutons_]

Generic Drugs Hit Backlog At FDA

No Plans to Expand Review Capabilities
By Marc Kaufman
Washington Post Staff Writer
Saturday, February 4, 2006; A01


At a time when low-cost generic drugs are being embraced as among the few ways to slow skyrocketing health care costs, the Food and Drug Administration has a backlog of more than 800 applications to bring new generic products to the market -- an all-time high.

As a result, experts say, fewer generic drugs will be available to consumers in the years ahead than the industry is ready and able to provide.


The FDA, however, has told Congress that the office that reviews new generics needs no additional money, and the agency has no plans to hire more reviewers.

( of course not, generics reduce the profits of Repug campaign donors )


"We are very aware that many, many people are waiting for more generics to be approved and that there is frustration about the backlog," said Gary Buehler, director of the agency's Office of Generic Drugs.

He said he expects a record number of applications this year -- and an even larger backlog -- because "we don't believe we'll be getting any staff increases in 2006." Buehler said his office received an all-time monthly high of 129 applications in December.

The Bush administration has strongly advocated generics as a way to hold down health care costs, and the director of the Centers for Medicare and Medicaid Services, Mark B. McClellan, said in an interview this week that an ever-growing number of generics is essential to controlling the cost to the government and seniors of the new Medicare prescription drug program.

( BUT! Another $70B for a bullshit war. dubya is all bullshit and no action, no policies )

In a recent federal report on health care costs, one of the few bright spots was a slowdown in the rate of prescription drug spending that was credited largely to the growing use of generics, which now account for more than half of all prescriptions."This huge backlog of generic applications is just unacceptable," said Rep. Henry A. Waxman (D-Calif.), one of the sponsors of the law that made generics more easily available two decades ago. "This is the time for the FDA to be ramping up its generic reviews, not to be falling so badly behind."

Last year, the generics office approved more than 450 applications, 23 fewer than the year before. The office took an average of 20.5 months to review each application, compared with 19.9 months in 1999, although by statute the agency is obliged to do the job within six months.

The FDA's Buehler said the agency gives priority to "first generic" applications, for drugs just losing patent protection, but documents show that the backlog for all generics is double what it was just three years ago.

As the backlog of generic applications has soared, the number of applications for new or reformulated drugs and biologics submitted by brand-name companies has remained consistently smaller than predicted.


But while the Office of Generic Drugs had about 200 employees to process almost 800 new applications last year, the offices that review new drugs had more than 2,500 employees for about 150 applications in 2004.

( FDA getting new proprietary drugs to the market benefits the the Repub campaign donor profits, while FDA keeping generics off the market protects and extends profits for proprietary drugs )


The generics office's budget was about $26 million last year, a fraction of the more than $400 million spent to evaluate and monitor new drugs and biologics, according to FDA documents. In response to questions from Congress, the agency said the generics program would have to make cuts in 2006 to offset pay raises.

( DoD is getting $425B next year. Repug Iraq war, $70/year, $6B/month )

"We have a kind of crazy situation now where the FDA's generic reviews -- which are supposed to be quicker because they're less complicated -- on average take longer than the new drug reviews," said Kathleen Jaeger, president of the Generic Pharmaceutical Association.
"The flood of applications is coming in generics, but the review resources mostly go to new drugs."

A generic drug, which comes on the market after another drug's patent expires and must have the same active ingredients as the drug it mimics, usually costs 60 to 90 percent less than the brand-name version. The cost drops the most with the first generic alternative to a brand-name drug, and it falls more as each new competitor reaches the market.

Consumer acceptance of generics has increased markedly in recent years. Drug experts say the tidal wave of demand reflects the high price of branded products, the large number blockbuster drugs going off patent, a big push by insurers and the government to encourage generic usage, and an influx of cheap medicines made by Asian manufacturers. These companies are filing applications to market drugs just coming off patent as well as lesser-used older medications that do not have generic competition.

Generic drugs now account for about 12 percent of the nation's $250 billion a year in drug spending and more than 53 percent of prescriptions filled. IMS Health, a company that tracks the industry, predicts that the percentage will exceed 65 percent within four years as several blockbuster drugs go off patent. Express Scripts, which manages pharmacy benefits for many insurers, estimates that the figure could be 70 to 75 percent by 2010.

Drug experts say more widespread use of generics could save billions.


( but the Repugs run the country to enrich the rich + corps, while screwing everybody else )


The Express Scripts study estimated that wider generic use could have saved $20 billion in 2004 alone. But because many generic drugs are antibiotics or other drugs that treat short-term conditions -- rather than the chronic problems treated by brand-name cholesterol, blood-pressure and antidepressant drugs -- only 37 percent of drugs dispensed, as opposed to prescriptions, are generic, according to IMS Health.

The FDA backlog is expected to balloon in the next few years. An unprecedented $60 billion to $70 billion a year worth of brand-name drugs -- such as Zocor, Zoloft, Pravachol and Ambien -- will come off patent in the United States over the next four years, creating opportunities for spirited generic competition and greatly reduced prices.

"It's pretty simple -- the more generics we have, and the more quickly we get them, the more savings for consumers," said Steve Miller, author of the Express Scripts study.

Mark Merritt, president of the Pharmaceutical Care Management Association, which represents pharmacy benefit managers, said 90 percent of the time doctors and patients agree to switch to a newly approved generic by the next refill.

But without an increase in staffing at the Office of Generic Drugs, advocates of generics say, the public will get those savings more slowly, and sometimes not at all.

The view within the FDA appears to be quite different. In testimony before Congress last summer, then-FDA Commissioner Lester M. Crawford said the agency was approving on average one generic drug per day, calling that a sign that "the system seems to be working" and that "we are meeting our deadlines." He said there was no need for additional staff in the generics office.

( another Repub political operative botches his job:

FDA Commissioner Steps Down After Rocky Two-Month Tenure
By Marc Kaufman
Washington Post Staff Writer
Saturday, September 24, 2005; A07

Food and Drug Administration Commissioner Lester M. Crawford announced his resignation yesterday, just two months after he was confirmed for the job. His e-mail notice to the FDA staff gave no reason for his surprise decision to step down.

Sources familiar with his departure said Crawford was asked to resign, though it was unclear why. Crawford has had a stormy tenure at the agency, which has been beset by criticism from both the left and the right over its actions regarding drug safety and emergency contraception.

He was also accused before his confirmation of having an improper relationship with a female colleague -- a charge that independent investigators said both parties denied. The final report did note, however, significant discrepancies between Crawford's testimony and that of others in the commissioner's office. )

Some at the agency and in the industry say the answer is to have generic-drug makers do what brand-name makers did in the early 1990s -- pay "user fees" to finance new hires by the FDA. Today, user fees support about half the FDA staff that reviews new drug applications.But the generic drug industry includes hundreds of small firms, and its leaders say they cannot reach consensus on whether to accept user fees.

Others argue that since the low cost of generics has broad benefits for the public, Congress should be willing to pay for added staffing. That the administration has not asked for more money, some say, indicates that it favors the big drug companies.

( duh! )


"The branded industry has to be delighted by this backlog," said Jake Hansen, vice president for government affairs for Barr Laboratories Inc., a maker of generic drugs. "If they can't stop competition in the courts, stopping it as applications go through the regulatory process is just as effective. For consumers, to flatline or cut funding makes absolutely no sense."

Sharon Levine, who oversees drug utilization for the Kaiser Permanente health plan in Northern California, said it is essential for the FDA to speed the approval of new generics.

"The agency has done a good job of getting a wide range of generics onto the market so far, so it's worrisome if that flow might be slowing down," she said.


© 2006 The Washington Post Company

[Winehole23]

given the deferential, perfunctory manner of drug approval at the FDA, it's arguable the GOP did us all a favor:

http://www.forbes.com/sites/davidmaris/2012/10/10/fda-recall-points-to-serious-problems-at-the-fda/3/

[boutons_deux]

given the deferential, perfunctory manner of drug approval at the FDA, it's arguable the GOP did us all a favor:

http://www.forbes.com/sites/davidmaris/2012/10/10/fda-recall-points-to-serious-problems-at-the-fda/3/

Approved drugs, including prescription and OTC, kill 10Ks every year.

[Wild Cobra]

Approved drugs, including prescription and OTC, kill 10Ks every year.
How many do they save?

[Winehole23]

Approved drugs, including prescription and OTC, kill 10Ks every year.ergo, if the GOP slowed down approval of bioequivalents, they probably saved lives.

[boutons_deux]

How many do they save?

Do You Own Research
--WC

All drugs have side effects, the stronger the drug, the worse the side effects. And many extremely expensive, widely used drugs are FUCKING USELESS if not actually harmful.

[Winehole23]

ergo, the GOP saved lives by jamming up the pipeline and jacking up the cost.

you lose again.

[boutons_deux]

ergo, the GOP saved lives by jamming up the pipeline and jacking up the cost.

you lose again.

you can GFY, over and over and over

The FDA is a total fraud, a sham, stuffed employees, doctors, scientists who are nothing more than BigPharma lobbyists and shills.

BigPharma tests its own drugs, suppresses bad results (which are kept secret), hypes good results, in trials with too few patients and for too short of test period. In effect new drugs are in beta test, and patients are nothing more than guinea pigs, Ms of whom have been maimed or killed, costing BigPharma $10Bs in fines and compensation, as nothing more than the cost of doing business.

The drugs are then also promoted by BigPharma and docs for off-label (totally untested) uses. It's all revenue.

Big frauds: all statins, and cardiac stents.

[boutons_deux]

100s of stories like this over the decades

Big Pharma Company Mocked Patients Who Got "Jawbone Death" from Drug: "Ma Toot Hurts So Bad"

As early as 2004, Merck knew its blockbuster osteoporosis drug Fosamax was causing osteonecrosis of the jaw (ONJ) after in-office dental procedures and ridiculed afflicted patients. The condition, also called jawbone death, occurs when traumatized tissue doesn't heal but becomes "necrotic" and dies. "Ma toot hurts so bad" mimicked Merck bone scientist Don Kimmel in a 2004 email to Merck health science consultant Sharon Scurato about the type of patient who was developing ONJ. Such a patient "could be an oral hog," wrote Kimmel, then a bone scientist in Merck's department of Molecular Endocrinology/Bone Biology and trained as a dentist--someone with pre-existing infections and periodontal disease who omits preventative care.


Newly available emails and internal Merck documents reveal the company was far from concerned or surprised when ONJ-links to Fosamax surfaced in the early 2000's and launched elaborate spin campaigns to keep the $3 billion a year pill afloat. In fact, animal studies revealed ONJ in rats given bisphosphonates (the class of drugs Fosamax belongs to) as early as 1977 Kimmel admitted under oath in 2008.

Thousands of lawsuits have been filed on behalf of patients who say they developed ONJ after dental procedures like tooth extraction because they took Fosamax. Treating ONJ is almost impossible said dentists and oral surgeons quoted the Review-Journal in 2005, because "further surgery in an effort to correct the problem only exacerbates it, leaving the patient with even more exposed bone and even more disfigured," Jaw removal, bone grafts, and even tracheostomies were reported by the News-Press in 2006. "Even short-term oral use of alendronate [Fosamax] led to ONJ in a subset of patients after certain dental procedures were performed,” read a study in the Journal of the American Dental Association in 2009.

Merck withheld crucial safety data from the American Society for Bone and Mineral Research (ASBMR) when the group sought to develop a position paper on bisphosphonate-related ONJ. Of 428 suspected ONJ cases related to Fosamax, 378 of which were highly likely to be ONJ, only 50 cases were shared with ASBMR, according to court documents. "I see the 50 with regard to the postmarketing," admitted Thomas Bold, Merck's director of clinical risk management and safety surveillance in 2009, upon viewing the slides Merck provided to ASBMR. "I don't see 378 mentioned and I don't know why that is the case," he conceded.

http://www.alternet.org/print/drugs/big-pharma-company-mocked-patients-who-got-jawbone-death-drug-ma-toot-hurts-so-bad

yawn, another new BigPharma drug, another new fucking over patients for $Bs in profits.

[boutons_deux]

FDA refuses to FOLLOW EUROPE and ban BPA, due to BigChem corrupting FDA and Congress.

Study Shows BPA Exposure in Fetal LiversBPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

"The general message from our research is that people have to be cognizant of the fact that the adult body may be able to deal with a particular exposure but a developing fetus may not,"

Previous animal studies have associated BPA with breast and prostate cancer, and reproductive and behavioral abnormalities. Some research on effects to human health has tied BPA to cardiovascular disease, miscarriage, decreased semen quality and childhood behavioral issues. The chemical also may impact metabolism, diabetes and obesity, although more studies are required to determine its effects.

http://www.sciencedaily.com/releases/2012/12/121203131658.htm

BPA, along with other BigChem's endocrine disruptors, has the wonderful effect of feminizing male fetuses. Measurements of male babies' anal-genital distance shows reduction towards female anal-genital distance, and of course smaller, less masculine genitals. But, BigChem's profits MUST be protected.

[admiralsnackbar]

Whose job is it to maintain the anal-genital distance tables, I wonder?

Some job.

[admiralsnackbar]

By the by... why did you post something from six years ago, Boutons? And do you really believe Pharma doesn't own the Dems, too?

Oh, I see... it was a necro-bump.

My mistake :lol

[boutons_deux]

Whose job is it to maintain the anal-genital distance tables, I wonder?

Some job.

job? why does it have to be anybody's job?

[admiralsnackbar]

job? why does it have to be anybody's job?

A fair point -- I hadn't considered the possibility of hobbyists tracking variations in anal-genital distances relative to gender over time.

Some hobby.

[boutons_deux]

A fair point -- I hadn't considered the possibility of hobbyists tracking variations in anal-genital distances relative to gender over time.

Some hobby.

It's not a hobby. It's part of evaluating/measuring each newborn. The medical job is measuring, not maintaining anatomicial distances.

[TeyshaBlue]

dup.

[TeyshaBlue]

lol...thread lies dormant for 6 years (like most of the bot's posts) and WH revives it? Fucking Frankenstein!

[boutons_deux]

ergo, if the GOP slowed down approval of bioequivalents, they probably saved lives.

BigPharma and its corrupt enforcer the FDA work to protect BigPharma's patented drug income against generics and importation of cheaper BigPharma drugs. Rest assured that BigPharma revenue is ALWAYS the BigPharma/FDA priority, NOT patient care.

[boutons_deux]

lol...thread lies dormant for 6 years (like most of the bot's posts) and WH revives it? Fucking Frankenstein!

TB! :lol Excellent contribution, as always.

[boutons_deux]

The Repug/VRWC blind ideology of deregulation and non-enforcement works wonders for BigAg and BigFood, and of course, is a huge stimulus for the health care sector.

Why Isn't the FDA Stopping The Epidemic of Foodborne Illness?

he United States is experiencing what amounts to an epidemic of foodborne illnesses. According to the CDC, there are about 48 million cases of food poisoning a year, leading to more than 128,000 hospitalizations and more than 3,000 deaths. E. coli in spinach and fruit juice, salmonella in eggs and jalapeño peppers, listeria not only in cantaloupes but in cheese and bagged lettuce—the toll from foodborne bacteria is mind-numbing.


With the exception of E. coli infections, the rate of outbreaks from other pathogens tracked by the CDC has been rising since 2007. The decline in E. coli–related illnesses is in part the result of strong actions taken by the Department of Agriculture in 1994. Following an outbreak caused by tainted hamburger from the Jack-in-the-Box fast-food chain that killed four children, the agency declared E. coli 0157:H7, the strain that sickened the children, an adulterant, making it illegal for companies under USDA jurisdiction to sell food contaminated with the bug. Meat producers took measures to eliminate it from their facilities. But potentially fatal bacteria other than E. coli have yet to be declared adulterants.


Some of the FDA’s deficiencies can be attributed to the haphazard manner in which it has grown. In contrast to the Environmental Protection Agency, which was created in 1970 to bring all federal environmental activities into a single, powerful unit with a clear mandate, the FDA expanded and occasionally contracted over decades in response to crises and pressure from public interest groups and corporate lobbyists. The agency originated in 1852, when it consisted of a single chemist working in the Department of Agriculture. It had no regulatory duties until 1906, when muckraking journalists’ horror stories [4] about food-processing facilities inspired passage of the Federal Food and Drugs Act. In 1937, hundreds of deaths from a new sulfa drug propelled passage of the Food, Drug, and Cosmetic Act to prevent similar health disasters. In the 1950s and 1960s, laws addressing pesticide residues, food additives, and color additives gave the agency greater control over food safety.

The FDA considers fresh produce to be "high risk" and therefore a priority for inspection. But until people started dropping dead, the Jensen facility had never once in its 20-year history been inspected by the FDA. Like most produce companies, Jensen used third-party auditors to certify its handling systems. On July 25, at about the same time the first people were being sickened by contaminated cantaloupe, one such auditor, a representative of Bio Food Safety [7], a Texas-based company whose website advertises "quality service at an unbelievable price," visited Jensen for four hours and blessed the plant with a "superior" rating of 96 percent.

http://www.motherjones.com/print/209291

[CosmicCowboy]

FWIW the top drug companies pretty much contribute equally to Dems and Repubs.

[boutons_deux]

FWIW the top drug companies pretty much contribute equally to Dems and Repubs.

they can afford it, with about the highest profit margins of the Top200, and after spending $60B on advertising and half as much on research/testing.

It's exclusively the Repugs who blame their hated govt and regulations for all that ills USA, not the Dems.

[CosmicCowboy]

they can afford it, with about the highest profit margins of the Top200, and after spending $60B on advertising and half as much on research/testing.

It's exclusively the Repugs who blame their hated govt and regulations for all that ills USA, not the Dems.

Boo loves his government?

[TeyshaBlue]

I can't construct a cogent sentence. :cry

[boutons_deux]

FDA refuses to FOLLOW EUROPE and ban BPA, due to BigChem corrupting FDA and Congress.

Study Shows BPA Exposure in Fetal Livers

BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

"The general message from our research is that people have to be cognizant of the fact that the adult body may be able to deal with a particular exposure but a developing fetus may not,"

Previous animal studies have associated BPA with breast and prostate cancer, and reproductive and behavioral abnormalities. Some research on effects to human health has tied BPA to cardiovascular disease, miscarriage, decreased semen quality and childhood behavioral issues. The chemical also may impact metabolism, diabetes and obesity, although more studies are required to determine its effects.

http://www.sciencedaily.com/releases/2012/12/121203131658.htm

BPA, along with other BigChem's endocrine disruptors, has the wonderful effect of feminizing male fetuses. Measurements of male babies' anal-genital distance shows reduction towards female anal-genital distance, and of course smaller, less masculine genitals. But, BigChem's profits MUST be protected.

Here's yet another gift from corporate BigAg, BigChem, BigFood

Scientists Warn of Sperm Count Crisis

Between 1989 and 2005, average sperm counts fell by a third in the study of 26,000 men, increasing their risk of infertility. The amount of healthy sperm was also reduced, by a similar proportion.

The decline occurred progressively hroughout the 17-year period, suggesting that it could be continuing.

"Now, there can be little doubt that it is real, so it is a time for action. Something in our modern lifestyle, diet or environment is causing this and it is getting progressively worse. We still do not know which are the most important factors but the most likely are … a high-fat diet and environmental chemical exposures."

Sperm count: How to boost it

1. Wear loose underwear – to make healthy sperm the testicles need to be below body temperature.

2. Eat food low in saturated fat.

3. Avoid smoking, drinking, using drugs and becoming obese.

4. Reduce exposure to industrial chemicals such as those used in making plastics – they can mimic the female hormone oestrogen countering male hormones.

http://www.alternet.org/personal-health/scientists-warn-sperm-count-crisis

"Eat food low in saturated fat" should be qualified to "Eat food low in mammalian, industrial saturated fat".

[CosmicCowboy]

Sperm counts decrease while teen pregnancies rise. Are the ones that are left just working harder?

[SA210]

http://ct.politicomments.com/ol/pc/sw/i53/2/10/29/pc_9ca03257efcb5b5e6e2d1476add10a6f.jpg

[boutons_deux]

http://ct.politicomments.com/ol/pc/sw/i53/2/10/29/pc_9ca03257efcb5b5e6e2d1476add10a6f.jpg

... should mention the Ms of people maimed or killed by FDA-approved drugs.

to be compared with the the how-many? maimed or killed by Schedule I marijuana.

[SA210]

http://sphotos-a.xx.fbcdn.net/hphotos-snc7/391884_393658354041847_1147564556_n.jpg

[TeyshaBlue]

Is there a beneficial drug on the planet?

[Wild Cobra]

Is there a beneficial drug on the planet?
acetylsalicylic acid comes to mind.

[TeyshaBlue]

Is there a beneficial drug on the planet?

lol motherfuckin' crickets.

[boutons_deux]

a lot of drugs are beneficial, but they all have side effects, some debilititating, maiming, fatal.

TB :lol

[TeyshaBlue]

a lot of drugs are beneficial, but they all have side effects, some debilititating, maiming, fatal.

TB :lol

You do realize that solutions are often substituting one set of issues with another, right?

lol simpleton.

[boutons_deux]

You do realize that solutions are often substituting one set of issues with another, right?

lol simpleton.

Do you realize you're defending the corrupt BigPharma and FDA, right?

TB :lol

[TeyshaBlue]

Do you realize you're defending the corrupt BigPharma and FDA, right?

TB :lol

No. I'm actually adding context to your talking point driven argument, such that it is.

[TeyshaBlue]

on point: There are many, if not the majority of drugs whose side effects are well known. These possible side effects are then weighed against against possible benefits. In the resultant cost/benefit analysis, sometimes the the possibility of side effects is lesser than the known positive effects of treatment. This results in a solution. A doctor will make this determination routinely, even against the backdrop of Big Pharma's caveats.

Your argument appears as : Drugs are bad because of side effects which, apparently, nobody knows about or ignores because FDA/Big Pharma uses a Jedi mind-trick on unsuspecting doctors.

Supporting your arguments are the cases of drugs which have had absurdly negative reactions. Yeah, they're out there. But, what does this subset represent within the context of all prescription medications?
Does the existence of this yet undefined subset require the vilification of the FDA and destruction of Big Pharma?

[TeyshaBlue]

I can feel the "But if it costs one life!" argument emerging.

[SA210]

http://sphotos-b.xx.fbcdn.net/hphotos-snc6/197827_520671047951973_939422050_n.jpg

[Winehole23]

lol...thread lies dormant for 6 years (like most of the bot's posts) and WH revives it? Fucking Frankenstein!store never closes. there's no such thing as a necro bump: history is continuous.

[Winehole23]

recollection, not so much . . .

[boutons_deux]

Prescription Drug Spending Per Senior 1992-2010
----------------------------------------
Year Prescription Drug Expenditures per Senior(year)
----------------------------------------
1992 $ 559
1994 $ 648
1996 $ 769
1998 $ 984
2000 $ 1,205
2005 $ 1,912
2010 $ 2,810

Number of Prescriptions for Seniors 1992-2010
-----------------------------------
Year Number of Prescriptions per Senior
-----------------------------------
1992 19.6
1994 20.7
1996 22.6
1998 26.5
2000 28.5
2005 34.4
2010 38.5

Number of Different Prescription Drugs Taken Daily
None 18%
1-2 36%
3-4 25%
5+ 21%

http://answers.google.com/answers/threadview/id/563761.html

The BigPharma propaganda has convinced, sumbliminally hypnotized Americans that popping pills is the solution for everything.

google "us military prescription drug abuse" to see how BigPharma and US military collaborate to pump the military fulls of $10Bs of pills.

America is so fucked and unfuckable.

[boutons_deux]

I can feel the "But if it costs one life!" argument emerging.

On July 26, 2000, the Journal of the American Medical Association published Starfield's review, "Is US health really the best in the world?" Starfield revealed the following facts:


In the US, the annual death rate, as a direct result of medical treatment, is 225,000 people. Of those, 106,000 are killed by FDA-approved pharmaceutical drugs. The other 119,000 are killed by medical mistreatment in hospitals. This makes medically caused death the third leading cause of mortality in America.


In 2009, I interviewed Dr. Starfield.


http://jonrappoport.wordpress.com


She assured me that, since the publication of her review in 2000, no federal agency had contacted her to ask for help in fixing this unconscionable horror, and no agency had undertaken a significant program to reverse the third leading cause of death in the US.


Aside from the medically caused death rate, there is medical maiming. In 2001, the LA Times published a shocking article by Linda Marsa.


http://articles.latimes.com/2001/jan/08/health/he-9609


The article revealed that, in addition to the deaths, 2.1 million more people were admitted to US hospitals every year, as a result of severe reactions to pharmaceutical drugs. And, every year, there were 36 million adverse drug reactions in America.

http://www.naturalnews.com/z038249_cancer_surgeon_John_Hopkins.html

"cost one life" TB :lol

The right-wing fucktard: we want "conserve" the bad shit and make them worse! It's the right-wing philosophy!

[TeyshaBlue]

lol strawman lol natural news. lol unsupported quotes. lol simpleton.

[TeyshaBlue]

I can drink a bottle of grapefruit juice and put myself in the hospital within the hour due to the way it interacts with one of the medications I have to take.

So, yeah...lol unsupported stats.

[TeyshaBlue]

I found something on a blog that makes me right!!!!1111! I don't understand it, but it's what I believe!!!!!

Nobody is defending Big Pharma, dolt.
Just trying to place a little context into your breathlessly vacuous arguments which scream "Throw out the baby with the bathwater!".

[boutons_deux]

lol strawman lol natural news. lol unsupported quotes. lol simpleton.
the quotes have links

TB :lol GFY

[TeyshaBlue]

I read the links, dolt. I know you didn't. There were no stats or studies anywhere.

lol simpleton.

[TeyshaBlue]

You did notice that the LA Times link was broken, right?

Fucking moron.

[TeyshaBlue]

But keep dodging/ignoring the salient points. It's what thinkprogress tells you to do.

[SA210]

I can drink a bottle of grapefruit juice and put myself in the hospital within the hour due to the way it interacts with one of the medications I have to take.



Because that unnatural chemically engineered medication/poison doesn't belong in your body, tbh.

[TeyshaBlue]

Because that unnatural chemically engineered medication/poison doesn't belong in your body, tbh.

If that unnatural, chemically engineered medication was not in my body, I wouldn't be walking today. http://homerecording.com/bbs/images/smilies/facepalm.gif

BTW, it's a biologic drug.

[TeyshaBlue]

Stick to stuff you know something about, if there is any topic that meets that criteria.

[SA210]

On July 26, 2000, the Journal of the American Medical Association published Starfield's review, "Is US health really the best in the world?" Starfield revealed the following facts:


In the US, the annual death rate, as a direct result of medical treatment, is 225,000 people. Of those, 106,000 are killed by FDA-approved pharmaceutical drugs. The other 119,000 are killed by medical mistreatment in hospitals. This makes medically caused death the third leading cause of mortality in America.



Amazing how 3,000 died on 9/11 and we used that to justify illegal war and murdering of over 2 million innocents in the process because of it.

Yet FDA and Big Pharma murder well over 100,000 every single year of our own citizens with unnatural poisonous drugs that they know are harmful..Terrorism?

[TeyshaBlue]

Amazing how 3,000 died on 9/11 and we used that to justify illegal war and murdering of over 2 million innocents in the process because of it.

Yet FDA and Big Pharma murder well over 100,000 every single year of our own citizens with unnatural poisonous drugs that they know are harmful..Terrorism?

murdered. You're a ridiculous person.

[clambake]

have you considered one of those religious healers?

[SA210]

Stick to stuff you know something about, if there is any topic that meets that criteria.

I know they are poisons for the most part, and made mostly for profit and not our health. I know they only mask problems instead of cure them, and only create other problems in the process. Are they all 100% useless, always? I wouldn't say that. But mostly they are. They are ok imo in RARE cases of emergency really (ER) , but then they should be cleansed out once out of emergency status. But the standard practice of prescribing a drug for any and every ailment and for every doctor visit, for anything is a sure way of staying unhealthy and causing other sickness and disease for yourself in the long run. It may help you walk right now, but it's causing a problem somewhere else. Those quarter million people harmed or killed by these drugs every year know something about that. Eventually the living person thinking they are just fine eventually becomes one of those dead, whether it be by liver failure due to the drugs, cancer or whatever. Taking drugs as a norm will certainly guarantee a weak immune system. Sad, but true.

[cantthinkofanything]

Amazing how 3,000 died on 9/11 and we used that to justify illegal war and murdering of over 2 million innocents in the process because of it.

Yet FDA and Big Pharma murder well over 100,000 every single year of our own citizens with unnatural poisonous drugs that they know are harmful..Terrorism?

It's probably just part of the plan to take some of those 100,000 out of the workforce and help the unemployment numbers.

[SA210]

murdered. You're a ridiculous person.

If they know it's harmful, it's murder. And they do know it's harmful. There is nothing ridiculous about telling that truth, maybe unpopular because everyone is so brainwashed into thinking we need to live on these drugs, but it's still true.

[boutons_deux]

murdered. You're a ridiculous person.

BigPharma suppresses the results of their own too-short trials with too-few guinea pigs. Putting essentially untested drugs on the market when BigPharma knows the sometimes fatal side effects IS MURDER.

[cantthinkofanything]

BigPharma suppresses the results of their own too-short trials with too-few guinea pigs. Putting essentially untested drugs on the market when BigPharma knows the sometimes fatal side effects IS MURDER.

involuntary manslaughter at best

[SA210]

Big Pharma and FDA heads should be on Most Wanted list, along with a lot of politicians.

[SA210]

involuntary manslaughter at best

It's very voluntary tbh, in the name of $$$$

[boutons_deux]

involuntary manslaughter at best

"Corporations are people, my friend"

... except when they commit murder.

[SA210]

http://sphotos-b.xx.fbcdn.net/hphotos-ash4/429499_10151173559308284_34525806_n.png

[TeyshaBlue]

If they know it's harmful, it's murder. And they do know it's harmful. There is nothing ridiculous about telling that truth, maybe unpopular because everyone is so brainwashed into thinking we need to live on these drugs, but it's still true.

You're broad brush characterization of an entire industry is devoid of anything approaching rational analysis. When you use terms like "everyone is so brainwashed", you demonstrate your inability to approach a viewpoint rationally. You share that trait with boutons. Congrats, I guess.

[boutons_deux]

"characterization of an entire industry"

http://www.propublica.org/special/big-pharmas-big-fines

https://www.commondreams.org/headline/2012/09/28-1

http://the2012scenario.com/accountability/big-pharma-and-pandemics/big-pharma-promotes-illegal-off-label-drug-uses/

TB :lol Giving BigPhama the benefit of the doubt :lol

[SA210]

You're broad brush characterization of an entire industry is devoid of anything approaching rational analysis. When you use terms like "everyone is so brainwashed", you demonstrate your inability to approach a viewpoint rationally. You share that trait with boutons. Congrats, I guess.

I assume you have the intelligence to understand that "everyone" isn't exactly every living being in America, because I obviously am not one of them. It's interesting though you would bring this up, because you clearly are one of them, at least it appears that way. It's a broad stroke because it's true. Let me use the word "most" then. "Most" people are brainwashed into thinking that pharmaceuticals and over the counter drugs are good for them, or a normal way of life, and that they are a necessary part of getting "healthy" when they are sick, and they really aren't. They keep you sick and make matters worse. It's more than rational. It's fact. Proper diet of natural unprocessed foods, exercise and supplements are the best way to go in "most" cases.

[TeyshaBlue]

"characterization of an entire industry"

http://www.propublica.org/special/big-pharmas-big-fines

https://www.commondreams.org/headline/2012/09/28-1

http://the2012scenario.com/accountability/big-pharma-and-pandemics/big-pharma-promotes-illegal-off-label-drug-uses/

TB :lol Giving BigPhama the benefit of the doubt :lol

First link is dead. Get a grownup to help you.

Second link is fraud not murder. One of these things is not like the other.

Third link is dead on.

As I said earlier (since your asinine narrative filters everything out that you don't understand), Big Pharma has criminal liablity. Never said otherwise, dolt.
On the other hand, that liability does not extend to everything they do, which is what SA210 is pushing with his "everyone's brainwashed" bullshit.
Couple that with your stunted "VWRC/Repug/MIC/UCA/Human American..etc" stew of vapid talking points, and the case you could make gets crushed by your own idiocy.

[TeyshaBlue]

I assume you have the intelligence to understand that "everyone" isn't exactly every living being in America, because I obviously am not one of them. It's interesting though you would bring this up, because you clearly are one of them, at least it appears that way. It's a broad stroke because it's true. Let me use the word "most" then. "Most" people are brainwashed into thinking that pharmaceuticals and over the counter drugs are good for them, or a normal way of life, and that they are a necessary part of getting "healthy" when they are sick, and they really aren't. They keep you sick and make matters worse. It's more than rational. It's fact. Proper diet of natural unprocessed foods, exercise and supplements are the best way to go in "most" cases.

Descriptors like everyone and most are meaningless. Until you quantify them, just keep saying "everybody".
I am what I am...a pragmatist that understands some things are good. Some things are bad. Rarely is something 100% either.
Proper diet and natural unprocessed foods could be fed to me in bed, cause that's where I'd be without those nasty poisons keeping my immune system suppressed.

[SA210]

"characterization of an entire industry"

http://www.propublica.org/special/big-pharmas-big-fines

https://www.commondreams.org/headline/2012/09/28-1

http://the2012scenario.com/accountability/big-pharma-and-pandemics/big-pharma-promotes-illegal-off-label-drug-uses/

TB :lol Giving BigPhama the benefit of the doubt :lol

Sadly, they usually just ignore all the links or try to find a made up flaw in them (source, youtube, etc) rather than actually trying to understand them, because at the end of the day they just want their damn drugs and war. And that doesn't heal anything.

[TeyshaBlue]

No, I read the links. lol @ "they".

Grow the fuck up.

[SA210]

Descriptors like everyone and most are meaningless. Until you quantify them, just keep saying "everybody".
I am what I am...a pragmatist that understands some things are good. Some things are bad. Rarely is something 100% either.
Proper diet and natural unprocessed foods could be fed to me in bed, cause that's where I'd be without those nasty poisons keeping my immune system suppressed.

"Most" people believe troops are innocent of murdering children because they were given orders to go to an illegal war, so they don't blame them for following orders. A very few minority could say the soldiers have a responsibility to NOT follow orders that kill innocent children. "Most" people would be offended at such an opinion, would you not agree? Same with drugs, most DO think vaccines and drugs are normal as a way of life, because that's what we are fed to believe growing up. That is NOT an untrue statement, so when you and others are told otherwise it seems ridiculous to you, when it's not at all. Doctors are taught to treat through drugs and surgery only, they aren't taught an alternative, and their true knowledge of proper diet is almost non existent.

[boutons_deux]

First link is dead. Get a grownup to help you.

Second link is fraud not murder. One of these things is not like the other.

Third link is dead on.

As I said earlier (since your asinine narrative filters everything out that you don't understand), Big Pharma has criminal liablity. Never said otherwise, dolt.
On the other hand, that liability does not extend to everything they do, which is what SA210 is pushing with his "everyone's brainwashed" bullshit.
Couple that with your stunted "VWRC/Repug/MIC/UCA/Human American..etc" stew of vapid talking points, and the case you could make gets crushed by your own idiocy.

the first link is legit, paste into your browser, then ask sysadmin why the board software does't post it as active link

"liability does not extend to everything they do"

bullshit. BigPharma's criminal trail of 100Ks of maimed people and 1000s of dead people over the past 20years+ totally denies them ANY BENEFIT OF THE DOUBT. They are guilty of testing fraud and other crimes until proven otherwise.

[TeyshaBlue]

the first link is legit, paste into your browser, then ask sysadmin why the board software does't post it as active link

"liability does not extend to everything they do"

bullshit. BigPharma's criminal trail of 100Ks of maimed people and 1000s of dead people over the past 20years+ totally denies them ANY BENEFIT OF THE DOUBT. They are guilty of testing fraud and other crimes until proven otherwise.






There's another trail to be followed. Can you figure out what it is?

[TeyshaBlue]

And no. Nobody is guilty until proven innocent. It's the other way around. But you know that.

[TeyshaBlue]

"Most" people believe troops are innocent of murdering children because they were given orders to go to an illegal war, so they don't blame them for following orders. A very few minority could say the soldiers have a responsibility to NOT follow orders that kill innocent children. "Most" people would be offended at such an opinion, would you not agree? Same with drugs, most DO think vaccines and drugs are normal as a way of life, because that's what we are fed to believe growing up. That is NOT an untrue statement, so when you and others are told otherwise it seems ridiculous to you, when it's not at all. Doctors are taught to treat through drugs and surgery only, they aren't taught an alternative, and their true knowledge of proper diet is almost non existent.

I'll give you the diet point. The rest is unquantified conjecture.

[SA210]

Truth bombs..


http://www.youtube.com/watch?v=8JF7TcPsmvI





In the US, the annual death rate, as a direct result of medical treatment, is 225,000 people. Of those, 106,000 are killed by FDA-approved pharmaceutical drugs. The other 119,000 are killed by medical mistreatment in hospitals. This makes medically caused death the third leading cause of mortality in America.

[TeyshaBlue]

Truth bombs..


http://www.youtube.com/watch?v=8JF7TcPsmvI

Truth bomb.

I can walk.

[SA210]

Truth bomb.

I can walk.

Another quarter million a year can't, they're dead.

[boutons_deux]

And no. Nobody is guilty until proven innocent. It's the other way around. But you know that.

bullshit

The BigPharma/RDA __SYSTEM__ is broken and corrupted by BigPharma, guilty of causing mulitple drug maiming, fatal disasters, more of which are, WITHOUT ANY DOUBT, to follow since the FDA penalties don't address the BigPharma/FDA system.

[TeyshaBlue]

Another quarter million a year can't, they're dead.

You haven't found that other trail either, I see.

[TeyshaBlue]

You haven't found that other trail either, I see.

Of course, you're not looking for it tho. Neither is boutons.

[Winehole23]

More hortatory than effective, but better than doing nothing.



Johnson & Johnson’s Actelion Pharmaceuticals, Celgene, and Gilead Life Sciences are all potentially blocking generic drug makers from accessing samples of their products, along with three dozen other drug companies — according to new data out Thursday from the FDA intended to publicly shame (https://www.statnews.com/2018/05/14/fda-generic-drugs-withholding-samples/)them for what it calls “gaming tactics.”

The new list (https://www.fda.gov/Drugs/DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/ucm607738.htm), which also includes Novartis, Pfizer, Valeant, and a host of other companies, is part of the Trump administration’s efforts to lower prescription drug prices that kicked off with a presidential address (https://www.statnews.com/2018/05/11/trump-drug-pricing-speech/) Friday. While broader regulatory and legislative changes must go through a complex and often lengthy process, top health officials have used their bully pulpits this week to call out a number of companies for what they consider bad behavior.https://www.statnews.com/2018/05/17/fda-shames-drug-companies-generics-access/

[boutons_deux]

More hortatory than effective, but better than doing nothing.


[/FONT][/COLOR]https://www.statnews.com/2018/05/17/fda-shames-drug-companies-generics-access/[/FONT][/COLOR]

it is "doing nothing", since BigPharma won't lose any money because somebody said something.

nothing's going to change, after window dressing and lip service, BigPharma will continue to bleed Americans of $100Bs annually, simply because they can, and nobody's stopping them, above all not the anti-regulation, BigPharma-loving/corrupted Repugs, who block Medicare from negotiating drug price, while partially privatizing Medicare at taxpayers' expense.

USA is the only industrial country that doesn't regulate drug prices.

[Winehole23]

we'll see whether whether pharmaceutical companies care about the risk to their reputation, also about whether anything will change.

your hypothesis that change is impossible is the deadest of all dead ducks.