A week it's normally enough for a sprained ankle, i had it many times playing soccer and you really can play without any problem with painkillers.
I am pretty sure that aggravating an ankle sprain usually isn't anything to worry about as it will just extend the recovery period.
That's why most players usually play thru sprains, Tim, Tony and Manu did many times, it's not big deal, actually he could have came back in game one with a shot and a strong bracing taping on the ankle.
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