The only real flaw in Manu's game is he can't play more than 30 minutes per game. He just doesn't have the stamina to go out there and give you 35-40 solid minutes over an 82 game schedule.
That is why every GM in the league would take TMac over Ginobili if you had to build a team around one of them. You can't really build a team around a guy who plays a little over half the game, no matter how good he is.
But given that, if I was going into game seven of the NBA Finals, Ginobili is one of the first players in the league I'd want on my team.