"have a family history"
genetic defects aren't the problem.
A family of fatties is most often not genetic, but the parent's fat and lifestyle "infecting" the children.
The biggest health problems US has today are self-inflicted, personal decisions:
smoking: 350K smoking lung cancer deaths/year.
overweight and obesity (eat too much and too much industrial food-like substances) leading to complications in nearly all other diseases and medical procedures, and leading to strokes, heart disease, diabetes, and very probably brain dysfunction in later years.
In the last year or so, there have been reports about how both the man's and woman's health and diet affects the quality of egg, the sperm, and health of the fetus, even PERMANENTLY.