Coronavirus is one mutation away from infecting millions

[hater]

These morons want 4 more years of this. God help us if that ever happens.

[Winehole23]

(Find the animated bar chart race at the link)

The numbers are the total confirmed normalized* cases per million for each state since June. A '10,000' means 1% of the state's population has tested positive of COVID since June 1. June 1 was chosen as it was around that time that countries worldwide that had been sucker-punched months before had the opportunity to apply proven preventative measures. It also provided an opportunity to contrast the resulting data with states' political affiliations, using the Cook Partisan Voting Index. The results suggest a strong correlation between a state's political leanings and its ability to employ proven science to slow the spread of COVID.

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* "Normalization" means the abnormalities in the data were evened out. For example, if there were 10 days in a row of a few cases/deaths a day and then one day of 1000... that looks awful and frenetic on a chart like this, even when framed in a per-week display. In reality, that 1000 is just a backlog catch-up, so I normalized it by spreading the thousand over previous dates for a more even / more realistic data. It works similarly when the total number of cases/deaths drops one day. Likely a correction from a previous report, I just subtracted the difference over previous dates to numbers that are probably closer to reality.

https://dangoodspeed.com/covid/total-cases-since-june

[Winehole23]

SARS-CoV-2 is a recently identified coronavirus that causes the respiratory disease known asCOVID-19. Despite the urgent need, we still do not fully understand the molecular basis ofSARS-CoV-2 pathogenesis. Here, we comprehensively define the interactions between SARSCoV-2 proteins and human RNAs. NSP16 binds to the mRNA recognition domains of the U1and U2 splicing RNAs and acts to suppress global mRNA splicing upon SARS-CoV-2 infection.NSP1 binds to 18S ribosomal RNA in the mRNA entry channel of the ribosome and leads toglobal inhibition of mRNA translation upon infection. Finally, NSP8 and NSP9 bind to the 7SLRNA in the Signal Recognition Particle and interfere with protein trafficking to the cellmembrane upon infection. Disruption of each of these essential cellular functions acts tosuppress the interferon response to viral infection.

https://www.cell.com/cell/fulltext/S...674(20)31310-6

The research was conducted primarily in the laboratory of Mitc Guttman, professor of biology and Heritage Medical Research Ins ute investigator. A paper describing the research appears online ahead of publication in the journal Cell.

The SARS-CoV-2 virus produces about 30 viral proteins. In this new research, the Guttman laboratory examined each of these and mapped out how they interact with the molecular components within human cells grown in a lab dish. They found that SARS-CoV-2 proteins attack three critical cellular processes to disrupt human protein production.

https://phys.org/news/2020-10-sars-c...lar-alarm.html

[Winehole23]

"Each of the processes that SARS-CoV-2 disrupts— splicing, translation, and protein trafficking—is so important for converting the human genetic material into proteins, and they are essential for human biology," says Guttman. "In fact, discovery of each of these processes has separately led to the awarding of a Nobel Prize. These are machines that are central to life. We cannot exist without them. SARS-CoV-2 has evolved in very specific ways to disable these cellular machines and disrupt their functions."

[tholdren]

Ifr less than flu

[TimDunkem]

Foldren is really invested in this. From grumpy old man upstairs to a permanent fixture as the Political Forum's bunker with about 10k posts in only a few months. Sad!

[Winehole23]

Ifr less than flu

in terms of deaths per million, when was the last time the flu killed as many people as COVID-19 in the USA?

[hater]

Foldren is really invested in this. From grumpy old man upstairs to a permanent fixture as the Political Forum's bunker with about 10k posts in only a few months. Sad!

You hate to see it

[ElNono]

You hate to see it

It is what it is

[tholdren]

in terms of deaths per million, when was the last time the flu killed as many people as COVID-19 in the USA?

How are deaths coded?

[ElNono]

^ another fold

[tholdren]

Foldren is really invested in this. From grumpy old man upstairs to a permanent fixture as the Political Forum's bunker with about 10k posts in only a few months. Sad!

Loloolooll

Here comes TimDunkem.
He cried about having it
He said all of Texas would be out of hospitals
He said more than 10x flu.

And here we are. Ifr less than flu.

Just like I said.


Lolooollloolollolll

He went into hysterical covid posting

[ElNono]

^ meltdown + fold... sad true story, tbh

[tholdren]

^ another fold

Elwrongwrong will use raw stats to attempt to prove a point , but have no idea how this data is calculated. Been doing this since January. Loloooll

Here he is. Still low level math.

[ElNono]

^ lashing out and taking it personal once found to be a fraud.

Get help, tbh

[tholdren]

Elwrongwrong will use raw stats to attempt to prove a point , but have no idea how this data is calculated. Been doing this since January. Loloooll

Here he is. Still low level math.

Elwrongwrong unable to answer questions and then cried about folding.



Loloooolll

Responds every time I post.

I win x2

[ElNono]

^ lashing out and taking it personal once found to be a fraud.

Get help, tbh

[tholdren]

Elwrongwrong unable to answer questions and then cried about folding.



Loloooolll

Responds every time I post.

I win x2

Bwahahahhahaha triggered and he folded

[ElNono]

^ lashing out and taking it personal once found to be a fraud.

Get help, tbh

[tholdren]

Elwrongwrong unable to answer questions and then cried about folding.



Loloooolll

Responds every time I post.

I win x2

[TimDunkem]

bwahaha Meeeellllltdooooownnnn

Just delete your account. No one reads your posts anymore, old man.

[baseline bum]

foldren ging up threads per par

[tholdren]

Elwrongwrong unable to answer questions and then cried about folding.



Loloooolll

Responds every time I post.

I win x2

[Winehole23]

@THEHermanCain urges us to resume life as normal

[tholdren]

Ifr less than flu