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  1. #23201
    Veteran DarrinS's Avatar
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    Wash your hands after using the john at the bar this time.
    Yeah, fomites are a major source of transmission. Lol

    Keep washing your groceries.

  2. #23202
    dangerous floater Winehole23's Avatar
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    Yeah, fomites are a major source of transmission. Lol

    Keep washing your groceries.
    public john, whole nother story, perhaps

  3. #23203
    Veteran DarrinS's Avatar
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    It doesn't have to. Selective pressure will produce the same mutations everywhere.
    Makes sense that it would

  4. #23204
    Veteran DarrinS's Avatar
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    public john, whole nother story, perhaps
    I haven't used a public bathroom in forever

  5. #23205
    Alleged Michigander ChumpDumper's Avatar
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    I haven't used a public bathroom in forever
    You just piss yourself after a drinking binge.

  6. #23206
    Veteran DarrinS's Avatar
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    You just piss yourself after a drinking binge.
    Piss when I get home.

  7. #23207
    Alleged Michigander ChumpDumper's Avatar
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    Piss when I get home.
    Sure, peepants.

    afraid of public restrooms

  8. #23208
    dangerous floater Winehole23's Avatar
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    I haven't used a public bathroom in forever
    I didn't ask, thanks for sharing.

  9. #23209
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    Makes sense that it would
    That's why all of these mutations were identified last March using a pseudotype virus by Paul Bieniasz. There's one single mutation he has identified which causes complete immune escape. We just need to apply more selective pressure, which are in the process of doing with the vaccines.

  10. #23210
    Alleged Michigander ChumpDumper's Avatar
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  11. #23211
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    I got it when it wasn't here

    per the CDC

  12. #23212
    Alleged Michigander ChumpDumper's Avatar
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    trying to blame others

  13. #23213
    my unders, my frgn whites pgardn's Avatar
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    It doesn't have to. Selective pressure will produce the same mutations everywhere. Chump will have to hide for life.
    Explain. not necessarily.
    We have already made a number of viral diseases much less common using vaccination.
    Polio has made a slight come back, but much less of a worldwide problem.

  14. #23214
    my unders, my frgn whites pgardn's Avatar
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    That's why all of these mutations were identified last March using a pseudotype virus by Paul Bieniasz. There's one single mutation he has identified which causes complete immune escape. We just need to apply more selective pressure, which are in the process of doing with the vaccines.
    Immune escape to what?

    We can produce new vaccines. We can make this much less serious and less widespread.

  15. #23215
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    You just piss yourself after a drinking binge.

  16. #23216
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    Explain. not necessarily.
    We have already made a number of viral diseases much less common using vaccination.
    Polio has made a slight come back, but much less of a worldwide problem.
    The specific mutations that are causing concern from a vaccination/acquired immunity perspective will occur naturally as selective pressure gets placed on the virus. Paul Bieniasz demonstrated this in the lab a year ago. E484K for example has been arising independently worldwide. Here's the latest variant which has E484K and more

    https://nymag.com/intelligencer/2021...t-we-know.html

    It has taken decades to make those viruses you speak of less common.

    Immune escape to what?

    We can produce new vaccines. We can make this much less serious and less widespread.
    Escape antibody immunity is what I meant. We'll need a booster down the road, not a big deal for those who aren't scared of vaccines.

  17. #23217
    Got Woke? DMC's Avatar
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    I didn't ask, thanks for sharing.
    The extreme concern over where someone takes a ing piss and here you're acting like you have no idea why someone would say that.

  18. #23218
    my unders, my frgn whites pgardn's Avatar
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    The specific mutations that are causing concern from a vaccination/acquired immunity perspective will occur naturally as selective pressure gets placed on the virus. Paul Bieniasz demonstrated this in the lab a year ago. E484K for example has been arising independently worldwide. Here's the latest variant which has E484K and more

    https://nymag.com/intelligencer/2021...t-we-know.html

    It has taken decades to make those viruses you speak of less common.



    Escape antibody immunity is what I meant. We'll need a booster down the road, not a big deal for those who aren't scared of vaccines.
    Ill put my bet on the vaccines. This is exactly why people abusing antibiotics produced strains of bacteria that are antibiotic resistant. But they have not taken over the world. These were bacteria that we do NOT have effective vaccines to. A good vaccine routine let us stay a step ahead of selection pressures. But it will be a constant battle.

    The research from teams at Caltech and Columbia, which has not yet been peer-reviewed, suggests that the variant known as B.1.526 could dampen the effectiveness of some current vaccine candidates

    Im going with we are good. Especially since we can produce new vaccines very quickly now. Lots of ways to attack a protein, not just one particular protein like the current vaccine basically does with Covid and Covid variants. Eventually we might get a variant arise that merely produces a cold and spreads. That would be good for us and the virus. And tends to happen over time. Not good to kill the host, just spread and not hurt them. Thats what this virus does with numerous bats in China.

  19. #23219
    dangerous floater Winehole23's Avatar
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    The extreme concern over where someone takes a ing piss and here you're acting like you have no idea why someone would say that.
    you're straining at a gnat

  20. #23220
    Veteran DarrinS's Avatar
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    249 new cases in Bexar. No deaths

  21. #23221
    dangerous floater Winehole23's Avatar
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    249 new cases in Bexar. No deaths
    Caseload is still pretty bad in the US, tbh. We're near the mid-summer peak, and we know now that was a bad time to relax restrictions.

  22. #23222
    my unders, my frgn whites pgardn's Avatar
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    Spring break should be cool.
    In Texas we have not learned a thing.

    Or Dan Patrick rules. “ I’m old and I willing to die“ especially now after he has been vaccinated.

  23. #23223
    Veteran hater's Avatar
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    RIP brazil

    Cases exploding all over

    Hospital Moinhos de Vento rents container to put bodies in Porto Alegre: 'It's a war field', says superintendent
    The ins ution had 119.7% of the ICU bed occupation this Tuesday (2). According to doctor Luiz Antônio Nasi, the morgue of the unit needed to be expanded to accommodate the dead by Covid.

  24. #23224
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  25. #23225
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    “I couldn’t sleep” after seeing the data, Murray, director of the Seattle-based Ins ute for Health Metrics and Evaluation, told Reuters. “When will it end?” he asked himself, referring to the pandemic. He is currently updating his model to account for variants’ ability to escape natural immunity and expects to provide new projections as early as this week.

    A new consensus is emerging among scientists, according to Reuters interviews with 18 specialists who closely track the pandemic or are working to curb its impact. Many described how the breakthrough late last year of two vaccines with around 95% efficacy against COVID-19 had initially sparked hope that the virus could be largely contained, similar to the way measles has been.

    But, they say, data in recent weeks on new variants from South Africa and Brazil has undercut that optimism. They now believe that SARS-CoV-2 will not only remain with us as an endemic virus, continuing to circulate in communities, but will likely cause a significant burden of illness and death for years to come.



    We all felt quite optimistic before Christmas with those first vaccines,” said Azra Ghani, chair in infectious disease epidemiology at Imperial College London. “We didn't necessarily expect such high-efficacy vaccines to be possible in that first generation.”

    The optimism proved short-lived. In late December, the UK warned of a new, more transmissible variant that was quickly becoming the dominant form of the coronavirus in the country. Around the same time, researchers learned of the impact of the faster-spreading variants in South Africa and in Brazil.

    The most recent change of heart was considerable, several of the scientists told Reuters. Shane Crotty, a virologist at the La Jolla Ins ute for Immunology in San Diego, described it as “scientific whiplash”: In December, he had believed it was plausible to achieve so-called "functional eradication" of the coronavirus, similar to measles.

    Now, “getting as many people vaccinated as possible is still the same answer and the same path forward as it was on December 1 or January 1,” Crotty said, “but the expected outcome isn't the same.”

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