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Couldn't you theoretically be infected, test positive, and still have these T-cells which fight off the infection?
The PCR test can pick up very low levels of virus.
As I've earlier ITT, I would love for nature to come to the rescue so Big Pharma can eat on their vaccine development, but what gives me pause about natural immunity being a consistent fact across populations is how many outbreaks in prisons, ships, and in neighborhoods saw infection rates over 60 percent, meaning not many were naturally immune (if 40 to 60 percent were naturally immune, the herd immunity threshold would've been in 10-20 percent). This phenomenon needs more study before it's justified to attempt any kind of herd immunity strategy.
Couldn't you theoretically be infected, test positive, and still have these T-cells which fight off the infection?
The PCR test can pick up very low levels of virus.
Not sure. I think so from what I've read.
you cant even understand death reporting.
Lololol
Tell us about probables..
Bwahahahahhahaha
Yes.
Preliminary studies indicate the viral load must be large for people to infect someone with a functioning immune system.
It looks like this virus may produce very large loads during certain periods in many people and do well in the air, not a good combination.
More to come.
I don't see anyone here stanning hydroxychloroquine. I've posted studies on anything that looks like it could be promising and hydroyxchloroquine could be one of them. Certain members here continuously try and on it just because of Trump. How bad does one's TDS have to be to that someone is rooting against something saving lives to try and dunk on Trump. It's pathetic.
Hydroxychloroquine could save up to 100,000 lives if used for COVID-19: Yale epidemiology professor
Dr. Harvey Risch, an epidemiology professor at Yale School of Public Health, said on Tuesday that he thinks hydroxychloroquine could save 75,000 to 100,000 lives if the drug is widely used to treat coronavirus.
“There are many doctors that I’ve gotten hostile remarks about saying that all the evidence is bad for it and, in fact, that is not true at all,” Risch told “Ingraham Angle," adding that he believes the drug can be used as a "prophylactic" for front-line workers, as other countries like India have done.
Risch lamented that a "propaganda war" is being waged against the use of the drug for political purposes, not based on "medical facts."
Researchers at the Henry Ford Health System in Southeast Michigan have found that early administration of hydroxychloroquine makes hospitalized patients substantially less likely to die.
The study, published in the International Journal of Infectious Diseases, determined that hydroxychloroquine provided a "66 percent hazard ratio reduction," and hydroxychloroquine and azithromycin a 71 percent reduction, compared with neither treatment.
In-hospital mortality was 18.1 percent overall; 13.5 percent with just hydroxychloroquine, 22.4 percent with azithromycin alone, and 26.4 percent with neither drug. "Prospective trials are needed" for further review, the researchers note, even as they concluded: "In this multi-hospital assessment, when controlling for COVID-19 risk factors, treatment with hydroxychloroquine alone and in combination with azithromycin was associated with reduction in COVID-19 associated mortality."
"Our results do differ from some other studies," Dr. Marcus Zervos, who heads the hospital's infectious diseases unit, said at a news conference. "What we think was important in ours ... is that patients were treated early. For hydroxychloroquine to have a benefit, it needs to begin before the patients begin to suffer some of the severe immune reactions that patients can have with COVID."
https://www.foxnews.com/media/hydrox...mpression=true
i think every person here has said they hoped hydroxychloroquine would pan out. its still irresponsible for anybody, let alone the president with his massive reach, to be claiming we have a miracle drug when that had not been clinically demonstrated because it causes people to drop their guard when we are far from being out of the woods
how strong does your TDS have to be to be constantly downplaying every aspect of the virus?
The Ford study has some flaws.
https://www.statnews.com/2020/07/08/...pay-the-price/The study that sparked the latest controversy was anything but randomized. Not only was it not randomized, outside experts noted, but patients who received hydroxychloroquine were also more likely to get steroids, which appear to help very sick patients with Covid-19. That is likely to have influenced the central finding of the Henry Ford study: that death rates were 50% lower among patients in hospitals treated with hydroxychloroquine.
Terrible methodology. Recent studies on hydroxy.
https://www.acpjournals.org/doi/10.7326/M20-4207
And I know the response to this is that it might have a prophylactic benefit, but that would be tricky study to implement. You have to purposely infect people (unethical) and you wouldn't know it was the drug that reduced symptom severity or the patient's own biology.Conclusion:
Hydroxychloroquine did not substantially reduce symptom severity in outpatients with early, mild COVID-19.
Trump Devotion Syndrome?
Here's honestly the best prevention we have against Covid severity right now: Don't be fat. Wear a mask, social distance, and practice good hygiene. You still might get infected doing the latter, but if you get infected while wearing mask or social distancing, the viral load will be reduced and lead to a chance of a better outcome.
what is the dosage per day in grams/Kg of bodyweight for HCQ?
Dubious HCQ has side effects.
https://www.rxlist.com/plaquenil-sid...rug-center.htm
Bannon acolyte TSA every day "flooding the zone with "
Are you accusing me of downplaying every aspect of the virus? I mock the fear porn the media pushes and call out bull when I see it, that isn't downplaying every aspect of the virus.
Stepped out on a limb there with that one considering it being used as a prophylactic was right there in the article
"Dr. Harvey Risch, an epidemiology professor at Yale School of Public Health, said on Tuesday that he thinks hydroxychloroquine could save 75,000 to 100,000 lives if the drug is widely used to treat coronavirus.
“There are many doctors that I’ve gotten hostile remarks about saying that all the evidence is bad for it and, in fact, that is not true at all,” Risch told “Ingraham Angle," adding that he believes the drug can be used as a "prophylactic" for front-line workers, as other countries like India have done."
Equally irresponsible was the study published in the Lancet that ElNono posted that ended up being retracted. Trials were halted and many will never start again because people were wrongfully scared about hydroxychloroquine deaths and now won't participate in trials.
He's going to have to produce some studies instead of anecdotes. We don't know if it works as a prophylactic. If India's frontline line workers are dying at a lower rate than ours, it could be any number of things. Indians are thinner. They live in a sunnier environment year around vs. many of the hardest hit regions (the Vitamin D theory). Etc, etc.Stepped out on a limb there with that one considering it being used as a prophylactic was right there in the article
"Dr. Harvey Risch, an epidemiology professor at Yale School of Public Health, said on Tuesday that he thinks hydroxychloroquine could save 75,000 to 100,000 lives if the drug is widely used to treat coronavirus.
“There are many doctors that I’ve gotten hostile remarks about saying that all the evidence is bad for it and, in fact, that is not true at all,” Risch told “Ingraham Angle," adding that he believes the drug can be used as a "prophylactic" for front-line workers, as other countries like India have done."
Problem is any objective study would be unethical. That said, I have nothing against taking it as a better safe than sorry measure, but the problem is it could cause shortages of the drug for Lupus patients and such.
Also, don't be vitamin D deficient.
I don't like fear porn, either, but the Team Reality contingent has been proven massively wrong and has likely done more harm than good with their ty information since I know it wound up on the screens of governors hungry for a reopening.
You can see my replies to Hart in that thread (Slap Jackson).
My point is in your effort to challenge fear porn, you're following the opinions of people who really don't know what they're talking about or doing and might be acting in bad faith. Not calling you out, just a heads up that no one who does know what they are talking about takes Team Reality seriously. They've been proven wrong at every pass.
agreed that the authors were irresponsible because they never got the database info audited in any way. i dont blame somebody like elnono for disseminating something which has purportedly gone through peer review and been published
it was correctly retracted, but yes, damage done.
It seems to me that you could get enough virus in your nose to trigger a positive PCR, but not necessarily become infectious.
Thus, infection with betacoronaviruses induces multispecific and long-lasting T cell immunity to the structural protein NP. Understanding how pre-existing NP- and ORF-1-specific T cells present in the general population impact susceptibility and pathogenesis of SARS-CoV-2 infection is of paramount importance for the management of the current COVID-19 pandemic.
https://www.nature.com/articles/s41586-020-2550-z
Bend over and I’ll show you a large load during a certain period
Was hoping it didn't come off like that but I'm not blaming ElNono nor calling him irresponsible in any way for posting it here.
There are trials being done here.
Study Description
Brief Summary:
The study is a double-blind, randomised, placebo-controlled trial that will be conducted in healthcare settings and other facilities directly involved in COVID-19 case management. We will recruit healthcare workers and other staff working in a facility where there are cases of either proven, or suspected, COVID-19, who can be followed reliably for 5 months. 40,000 participants will be recruited and we predict an average of 400-800 participants per site in 50-100 sites.
The participant will be randomised to receive either chloroquine or placebo (1:1 randomisation), or to hydroxychloroquine or placebo (1:1 randomisation). A loading dose of 10mg base/kg (four 155mg tablets for a 60kg subject), followed by 155 mg daily (250mg chloroquine phosphate salt/ 200mg hydroxychloroquine sulphate) will be taken for 3 months.
If the participant is diagnosed with COVID-19, they will take continue to take the study medication until:
90 days after enrolment (i.e., completion of kit)
hospitalised due to COVID-19 disease (i.e., not for quarantine purposes) in which case they will stop, or
advised to stop by their healthcare professional for other reasons
Episodes of symptomatic respiratory illness, including symptomatic COVID-19, and clinical outcomes will be recorded in the Case Record Form during the follow-up period.
https://clinicaltrials.gov/ct2/show/NCT04303507
There is one exception. Many researchers agree that a good case can be made for continuing to test whether hydroxychloroquine can prevent infection if given to people just in case they get exposed to the virus, for instance on the job at a hospital—a strategy called pre-exposure prophylaxis (PrEP). “You have a much better chance of preventing something with a weak drug than you have of curing a fully established infection,” says White, who runs one of the largest PrEP trials. He notes that doxycycline, an antibiotic, has long been used in malaria prophylaxis. “We would never treat anybody with it, it’s too weak. But it’s a very good prophylactic.”
Landray, however, is on the fence about continuing prophylaxis trials: “I suspect it’s one of these decisions where there isn’t a right or wrong.” It’s an important question, Bhadelia says, because an effective PrEP drug could have a major impact on the pandemic. Hydroxychloroquine, a cheap and widely available drug, is one of the few compounds that could fit the bill.
https://www.sciencemag.org/news/2020...event-covid-19
If it doesn't cause shortages for people who need it, then why not. Really nothing to lose.
Because Gummi knows best
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