What domestic items? We are a net importer. Our food is subsidized, so admittedly, that might not change a huge amount for production, but transportation costs will increase, so if inflation goes crazy, gas prices will sky rocket, thereby increasing food costs. And imports costing more will screw us...
If the dollar loses value, salaries won't react enough either, so for an extended period, people will be making the same amount, while their dollar gets less, not a good thing. People on fixed incomes will be screwed, namely old people. Old people also make up a fair percentage of population, and if they stop spending, our consumer driven society takes a hit. Large scale inflation is VERY bad.