I'm a huge believer in being able to change the pace of a game, which is why Manu was always so valuable off the bench. But I think this second unit can offer that on their own. I would love to see Pop put both Manu and Kawhi in to start the game. That leaves RJ to play against the opponents' subs, where he would be fine - he might even get a chance to play more of his old style game. The only problem I see is that Manu is by far our best backup PG right now. There's something to be said to having either him or Tony on the floor at all times, at least until Ford comes back.
What I'd really love to see is a starting five of Tim, Tiago, Leonard, Manu, and Tony. Even if the Tim/Tiago combo ended after 6-7 minutes, to be able to open the game with a dominating lineup, and setting the tone for the game... that could save a lot of grief in the latter stages. I really think that starting five could make things tough on just about any other team in the league.