This isn't fear of the Grizzlies, who are as flawed and mediocre as ever; it's the reality that the Spurs have been entirely unconvincing the entire season and the Grizzlies probably gaining confidence from the season series. What have you seen out of this team that makes you confident they do what they should and beat this team in 4 or 5?
I'm going 6, with the games being mostly close throughout.
As far as match-ups, if they labor to score the way they have since Gasol got injured, Dedmon could be limited to just the first 6 minutes of the 1st and 3rd quarters, with a 3 big rotation thereafter.
One that won't happen but should: Bertans playing backup small forward, since he should be able to be safely hidden on Ennis.