I believe that's just sweat + friction, probably caused from wearing jeans a lot. I've had the occasional problem with that in the past, but since I took up serious running a few months back and dropped 26 lbs so far, my inner thighs are tight and smoooooth as a baby's butt
Try some Gold Bond Powder, it's supposed to help anything.
(From what I've observed around these parts, Gold Bond could set up shop on every corner and never run out of sweaty, thigh friction producing customers)

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