Lots of natural substances and phyto-chemicals are extremely powerful, but Big Pharma can't make money from them, so Big Pharma won't finance the expensive human trials.
Sucking smoke deep into your lungs repeatedly is toxic, just like cigarette and most other smoke.
THC or whatever the active phyto-chemical is should be taken orally, sub-lingually, or transdermally.
As long as the marijuana promotors make smoking marijuana leaves for medicinal purposes as the primary method of delivery, they are hurting the chances of sick people to obtain the benefits.

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