I'm both sick and drunk, so take with a huge grain of paprika, but Anderson should start and Jefferson should come in with Hill to give Parker and Anderson a blow.
Why? Other than I said so ... Anderson is a small forward in the NBA. He's the best option they've got currently to compliment and augment the inside game of Duncan, Blair and Parker to start, and he's shown enough for me to believe he'll guard on the perimeter as well as any of their bigger guards/swing players. Plus, RJ comes in as option 1 or 2 and is forced to engage early. It's been quite apparent if he doesn't get involved early or see the ball go in the hole a couple of times early on, he becomes essentially a wallflower -- catch the ball, move the ball, don't-do-much-if-anything unless Moses has parted the sea or the only option is to make a play for himself.
Bottom line, this team's success -- as currently constructed -- depends upon their growth potential. If the team's able to get it done without a trade -- and maybe even with a trade -- it'll be because their youth became relevant; legitimate players the team's success is dependent upon. Thus, let them get their hacks in early; they need the reps (Blair and Anderson, specifically).
So if it's me, my starting 5 to start the season: Parker - Ginobili - Anderson - Blair - Duncan. Do it to it.
Whatcha thank 'bout dat?