Going by historical MNF figures and home/away really served you well in the Falcons/Saints game, didn't it?
Talent is also a real thing. The Vikings have one of the best secondaries in the NFL, but the Giants receiving corps is something else. It's far better than that of the Packers or any team the Vikings have seen thus far. The Giants have shown some of the best potential out of any NFL team so far on both ends but last game lost a close one due to fluke turnovers and a million fluke penalties, Norman getting in their head, drops, Eli's uncharacteristic late pick... overall a bunch of random events that didn't go their way.
Vikings are a solid team too and I think Bradford is an upgrade over Bridgewater and Diggs is excellent too... but you can't really go by their record last year because this year they have healthy DRC, Jenkins, Vernon, JPP. Can't really include Apple yet because he's raw but as for now you shut down Diggs and you should be okay on that end. Main issue is actually scoring on the Vikings, but the Giants have the best receiving corps in the league (for now) so we'll see... should be a close one. The kind Eli tends to win in the clutch (yes, I know he failed last time, but he won't twice in a row)
Giants by a field goal or touchdown, I say.