Coronavirus treatments and vaccines thread

[tholdren]

You actively ignore the countries who have done better.

better how?

[DarrinS]

You actively ignore the countries who have done better.

Germany, South Korea, Japan, motherfuckin Vietnam...

Should I name more?

[tholdren]

Germany, South Korea, Japan, motherfuckin Vietnam...

Should I name more?

no mask Nords.

Sweden

South Dakota

[ChumpDumper]

Germany, South Korea, Japan, motherfuckin Vietnam...

Should I name more?Sure, but are you sure you could stand it? Looks like it's hurting you.

[tholdren]

Sure, but are you sure you could stand it? Looks like it's hurting you.

sea lion

[tholdren]

Sure, but are you sure you could stand it? Looks like it's hurting you.

sea lion

[ChumpDumper]

sea lion


sea lionlol ducks

[tholdren]

lol ducks

Chumpdump troll

[DarrinS]

Sure, but are you sure you could stand it? Looks like it's hurting you.

Go here and sort by deaths per million in ascending order

https://www.worldometers.info/coronavirus/#countries

[tholdren]

People who have been confirmed with mild to moderate COVID-19 can leave their isolation without receiving a negative test, according to recently revised guidance from the Centers for Disease Control and Prevention.

Increasing evidence shows that most people are no longer infectious 10 days after they begin having symptoms of COVID-19. As a result, the CDC is discouraging people from getting tested a second time after they recover

[ChumpDumper]

Go here and sort by deaths per million in ascending order

https://www.worldometers.info/coronavirus/#countriesI have. That's why I asked what was your target for deaths in those countries since they are only delaying the inevitable according to you?

[tholdren]

People who have been confirmed with mild to moderate COVID-19 can leave their isolation without receiving a negative test, according to recently revised guidance from the Centers for Disease Control and Prevention.

Increasing evidence shows that most people are no longer infectious 10 days after they begin having symptoms of COVID-19. As a result, the CDC is discouraging people from getting tested a second time after they recover

Bwahahahaha

[Blake]

I have. That's why I asked what was your target for deaths in those countries since they are only delaying the inevitable according to you?

As long as we're not New York is what we seem to have so far

[tholdren]

As long as we're not New York is what we seem to have so far

Lllololol trying to ignore cdc news. Lollool with gossip

[ChumpDumper]

Lllololol trying to ignore cdc news. Lollool with gossipNo one's ignoring it.

Are you autistic?

[tholdren]

No one's ignoring it.

Are you autistic?

So admit you were wrong about 2 weeks and case count.

[ChumpDumper]

So admit you were wrong about 2 weeks and case count.You can't even explain what you're talking about.

So it's more gossip and lies from you.:tu

[tholdren]

You can't even explain what you're talking about.

So it's more gossip and lies from you.:tu

You said people needed to wait 2 weeks for isloation. Wrong

You said case count were actual infected contagious people. Wrong
You said cases reported daily was an accurate way to guage pandemic and spread. Wrong

All addressed in the link. This was stated 2 weeks ago by cdc and not reported by media

[ChumpDumper]

You said people needed to wait 2 weeks for isloation.Link that quote.

You said case count were actual infected contagious people.Link that quote.

You said cases reported daily was an accurate way to guage pandemic and spread.Link that quote.

Your claim.

Back it up.

[Winehole23]

Eric Topol: "theraputic implications for how to block cytokine storm"


AbstractCoronavirus disease 2019 (COVID-19) is a new pandemic disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)1. The C5a anaphylatoxin and its receptor C5aR1 (CD88) play a key role in the initiation and maintenance of several inflammatory responses, by recruiting and activating neutrophils and monocytes in the lungs1. We provide a longitudinal analysis of immune responses, including immune cell phenotyping and assessments of the soluble factors present in the blood and broncho-alveolar lavage fluid (BALF) of patients at various stages of COVID-19 severity: paucisymptomatic, pneumonia and acute respiratory distress syndrome (ARDS). We report an increase in soluble C5a levels proportional to COVID-19 severity and high levels of C5aR1 expression in blood and pulmonary myeloid cells, supporting a role for the C5a-C5aR1 axis in the pathophysiology of ARDS. Anti-C5aR1 therapeutic monoclonal antibodies (mAbs) prevented C5a-mediated human myeloid cell recruitment and activation, and inhibited acute lung injury (ALI) in human C5aR1 knockin mice. These results suggest that C5a-C5aR1 axis blockade might be used as a means of limiting myeloid cell infiltration in damaged organs and preventing the excessive lung inflammation and endothelialitis associated with ARDS in COVID-19 patients.

https://www.nature.com/articles/s41586-020-2600-6

[Winehole23]

attenuation of infection and lower mortality reported for patients who were given statins


Our data suggest that statin treatment is associatedwith a mild attenuation of SARS-CoV-2 infection invitro. In accordance, previous studies reported anamelioration of COVID-19 outcome in patients3,4,10.Although our COVID-19 intensive care unit cohortwas too small to confirm this beneficial effect ofstatins on infection outcome, we could detect anassociation of low HDL levels and increased all-causemortality. Reduced HDL levels in critical careCOVID-19 patients were previously reported13,however cause and consequence of this observationneed to be addressed in larger cohorts. As statinsreduce LDL and may increase HDL levels, statinmodulation of serum lipoprotein homeostasis may –inaddition to immunomodulatory and other yet unknowneffects - contribute to the previous observations ofbeneficial effects of statins in patients.https://www.medrxiv.org/content/10.1101/2020.07.13.20152272v1.full.pdf


A new study led by Chinese researchers in collaboration with UCLA's Dr. Yibin Wang, PhD, has shown that people hospitalized with COVID-19 who took statin drugs were less likely to die and less likely to need mechanical ventilation than those who did not take the cholesterol-lowering drugs. Hospitalized patients taking statins had a 5.2% mortality rate, compared to a 9.4% mortality rate in patients not taking statins from two groups of COVID-19 patients with matching clinic characteristics except statin usage. Statin use also was linked to lower levels of inflammation, and a lower incidence of acute respiratory distress syndrome and admission to intensive care units.https://www.uclahealth.org/statin-usage-is-linked-to-a-lower-death-rate-in-hospitalized-covid-19-patients

[ducks]

https://scontent-lax3-1.xx.fbcdn.net/v/t1.0-9/fr/cp0/e15/q65/116062323_3869260166422395_6902154599018887848_n.j pg?_nc_cat=109&_nc_sid=ca434c&efg=eyJpIjoidCJ9&_nc_ohc=u-fOvaguovUAX8nCvZs&_nc_ht=scontent-lax3-1.xx&tp=14&oh=b159434f0f244481a2e64d1ab4d5e77d&oe=5F4A5CCE

Lol 2005

[Winehole23]

https://scontent-lax3-1.xx.fbcdn.net/v/t1.0-9/fr/cp0/e15/q65/116062323_3869260166422395_6902154599018887848_n.j pg?_nc_cat=109&_nc_sid=ca434c&efg=eyJpIjoidCJ9&_nc_ohc=u-fOvaguovUAX8nCvZs&_nc_ht=scontent-lax3-1.xx&tp=14&oh=b159434f0f244481a2e64d1ab4d5e77d&oe=5F4A5CCE

Lol 2005what's the funny part?

[pgardn]

https://scontent-lax3-1.xx.fbcdn.net/v/t1.0-9/fr/cp0/e15/q65/116062323_3869260166422395_6902154599018887848_n.j pg?_nc_cat=109&_nc_sid=ca434c&efg=eyJpIjoidCJ9&_nc_ohc=u-fOvaguovUAX8nCvZs&_nc_ht=scontent-lax3-1.xx&tp=14&oh=b159434f0f244481a2e64d1ab4d5e77d&oe=5F4A5CCE

Lol 2005

Lol

Here is what happens if you actually go to the journal and the conclusion:

Chloroquine is effective in preventing the spread of SARS CoV in primate cell culture.


Do you have any understanding of the shit you put out?
This is typical Trump "facts". Distortion and disingenous statements to PURPOSELY confuse the country he is running.
And the ducks will follow in line.
This is why it was tried in the first place ducks.

Do you understand the bolded?

This is a bad as lying to your own people, good job ducks.

SARS not Covid 19
Cell Culture, not in bodies ducks.
Primate cells ducks, go back and look at the primate cells ducks, what did they use? Just want to see if you can read.

[Winehole23]

Abstract: Point of care diagnostics for COVID-19 detection are vital to assess infection quickly andat the source so appropriate measures can be taken. The loop-mediated isothermalamplification (LAMP) assay has proven to be a reliable and simple protocol that can detectsmall amounts of viral RNA in patient samples (<10 genomes per µL)(Nagamine, Hase, andNotomi 2002). Recently, Rabe and Cepko at Harvard published a sensitive and simpleprotocol for COVID-19 RNA detection in saliva using an optimized LAMP assay (Rabe andCepko, 2020). This LAMP protocol has the benefits of being simple, requiring no specializedequipment; rapid, requiring less than an hour from sample collection to readout; and cheap,costing around $1 per reaction using commercial reagents. The pH based colorimetric readoutalso leaves little ambiguity and is intuitive. However, a shortfall in many nucleic acid-basedmethods for detection in saliva samples has been the variability in output due to the presence ofinhibitory substances in saliva. Centrifugation to separate the reaction inhibitors from inactivatedsample was shown to be an effective way to ensure reliable LAMP amplification. However, acentrifuge capable of safely achieving the necessary speeds of 2000 RPM for several minutesoften costs hundreds of dollars and requires a power supply.We present here an open hardware solution- Handyfuge - that can be assembled with readilyavailable components for the cost of <5 dollars a unit and could be used together with the LAMPassay for point of care detection of COVID-19 RNA from saliva. The device is then validatedusing the LAMP protocol from Rabe and Cepko. With the use of insulated coolers for reagentsupply chain and delivery, the assay presented can be completed without the need for electricityor any laboratory scale infrastructure.

https://www.medrxiv.org/content/10.1101/2020.06.30.20143255v1.full.pdf (https://www.medrxiv.org/content/10.1101/2020.06.30.20143255v1.full.pdf)

[boutons_deux]

what's the funny part?


Why hasn't covid-19 reacted, after many attempts, to HCQ as SARS did?

Maybe because SARS is not Covid-19?

covid-19 is UNLIKE anything the medical people have ever seen, eg, covid-19 is NOT, and does not act like SARS, MERS, etc

[pgardn]

https://www.medrxiv.org/content/10.1101/2020.06.30.20143255v1.full.pdf (https://www.medrxiv.org/content/10.1101/2020.06.30.20143255v1.full.pdf)

Very cool.
Hand operated.
I would love to see the gearing to get the appropriate RPMs for centrifugation.

This could be beautiful stuff for testing anywhere.

[pgardn]

Lol

Here is what happens if you actually go to the journal and the conclusion:

Chloroquine is effective in preventing the spread of SARS CoV in primate cell culture.


Do you have any understanding of the shit you put out?
This is typical Trump "facts". Distortion and disingenous statements to PURPOSELY confuse the country he is running.
And the ducks will follow in line.
This is why it was tried in the first place ducks.

Do you understand the bolded?

This is a bad as lying to your own people, good job ducks.

SARS not Covid 19
Cell Culture, not in bodies ducks.
Primate cells ducks, go back and look at the primate cells ducks, what did they use? Just want to see if you can read.


Why hasn't covid-19 reacted, after many attempts, to HCQ as SARS did?

Maybe because SARS is not Covid-19?

covid-19 is UNLIKE anything the medical people have ever seen, eg, covid-19 is NOT, and does not act like SARS, MERS, etc

[Winehole23]

Very cool.
Hand operated.
I would love to see the gearing to get the appropriate RPMs for centrifugation.

This could be beautiful stuff for testing anywhere.if scalable and reliable, yes

[pgardn]

if scalable and reliable, yes

Hope so.
Because this could be incredibly handy.

[boutons_deux]

There's Growing Panic That Trump Will Rush A Vaccine To Save His Presidency.

That's Unlikely.

“I can’t see how this is done, frankly, before the middle of next year,” said one expert, of a coronavirus vaccine.

growing concern among health experts and Democrats that President Donald

Trump will rush a potentially faulty coronavirus (https://www.buzzfeednews.com/collection/coronavirus) vaccine before the election to save his presidency.

it’s highly unlikely even the bare minimum of clinical trial data from the administration’s “Operation Warp Speed” candidates will be available by November,

making any possible attempt to speed up a vaccine before the election extremely difficult.

“I cannot imagine that you would have data that shows efficacy and in a period of time that would be over the next few months.”

“The development of a new vaccine requires a dedication to science, coordination, transparency, truth, and fairness to all — and we have a President who stands for none of these things,” Biden said

The vaccine safety guardrails that do exist may be too high for Trump to get around, though, even if he tries to ignore them.

a faulty vaccine could cripple the country’s ability to ultimately defeat the coronavirus by destroying Americans’ remaining faith in vaccination.

“If a vaccine or any medication is pushed out there and

you find out 6 or 12 months later that there are health consequences or that it doesn’t work,

we will lose the confidence in our scientific ability —

not just on this but on anything in the future,”

“There is high stakes on this. We’ve got to get it right.”

“I can’t see how this is done, frankly, before the middle of next year,” Offit added.

so many scientific watchdogs oversee vaccine safety that the

Trump administration would be hard-pressed to jump over safeguards without creating blowback that wrecks public confidence in the vaccine.

communicating the vaccine’s safety was essential to getting people to get inoculated,

something more true than ever today.

“Not just the nation, but the whole world is going to be watching the safety data from these trials,” Koh said.

“This will be the most scrutinized safety data ever.”

https://www.buzzfeednews.com/article/danvergano/trump-vaccine-election-november (https://www.buzzfeednews.com/article/danvergano/trump-vaccine-election-november)

[DarrinS]

^drumpf doesn't control when vaccines are approved

[Will Hunting]

Lol Darrin’s Drumpf shtick is back

[Dirks_Finale]

https://www.youtube.com/watch?v=mV3urNCQOKM&amp;feature=youtu.be&amp;fbclid=IwAR14 JZ9rE8j8B1FW9Kd8Oxk5uQAH15Wk-asWsMcg1fy4sK2oqOZqfXxPLUw

[ElNono]

:lol OAN

[boutons_deux]

^drumpf doesn't control when vaccines are approved

Trash has installed his lickspittles in FDA, which was already, for years, corrupted with lobbyists and conflicted scientist whores and managers from BigPharma.

Trash has fucked up his entire life and his so-called Presidency, and he will try hard to fuck up the C19 vaccine thinking that's to his benefit.

[Winehole23]

MASKS INFRINGE FREEDOM

https://www.fastcompany.com/90524003/harvard-professor-develops-a-50-nasal-spray-to-thwart-the-spread-of-covid-19

[Winehole23]

Mr Murashko, quoted by Interfax news agency, said that the Gamaleya Institute, a research facility in Moscow, had finished clinical trials of a vaccine and that paperwork was being prepared to register it.

"We plan wider vaccinations for October," he said, adding that teachers and doctors would be the first to receive it.

Last month, Russian scientists said that early-stage trials of an adenovirus-based vaccine developed by the Gamaleya Institute had been completed and that the results were a success.
https://www.bbc.com/news/world-europe-53621708

[ElNono]

Trump health official: Time to ‘move on’ from hydroxychloroquine
Dr. Brett Giroir says the need is to find medicines that work.

A top official in the Trump administration's Covid-19 response effort said Sunday there was no evidence that hydroxychloroquine was an effective treatment for the virus, despite President Donald Trump's continued promotion of the malaria drug.

In an interview on NBC's "Meet the Press," administration testing czar Brett Giroir said he could not recommend hydroxychloroquine because trials "do not show any benefit."

"We need to move on from that and talk about what is effective, said Giroir, assistant secretary at the Department of Health and Human Services.

The warnings from administration officials have failed to dissuade the president from touting the treatment.

...

But Giroir on Sunday suggested that doctors would be unlikely to prescribe the drug. Anthony Fauci, the nation's leading infectious disease expert, has also dismissed the benefits of hydroxychloroquine in recent days.

"There may be circumstances, I don't know what they are, where a physician may prescribe it for an individual, but I think most physicians and prescribers are evidence-based and they're not influenced by whatever is on Twitter or anything else," Giroir said. "And the evidence just doesn't show that hydroxychloroquine is effective right now".

https://www.politico.com/news/2020/08/02/trump-health-official-hydroxychloroquine-390601

[Winehole23]

Trump health official: Time to ‘move on’ from hydroxychloroquine
Dr. Brett Giroir says the need is to find medicines that work.

A top official in the Trump administration's Covid-19 response effort said Sunday there was no evidence that hydroxychloroquine was an effective treatment for the virus, despite President Donald Trump's continued promotion of the malaria drug.

In an interview on NBC's "Meet the Press," administration testing czar Brett Giroir said he could not recommend hydroxychloroquine because trials "do not show any benefit."

"We need to move on from that and talk about what is effective, said Giroir, assistant secretary at the Department of Health and Human Services.

The warnings from administration officials have failed to dissuade the president from touting the treatment.

...

But Giroir on Sunday suggested that doctors would be unlikely to prescribe the drug. Anthony Fauci, the nation's leading infectious disease expert, has also dismissed the benefits of hydroxychloroquine in recent days.

"There may be circumstances, I don't know what they are, where a physician may prescribe it for an individual, but I think most physicians and prescribers are evidence-based and they're not influenced by whatever is on Twitter or anything else," Giroir said. "And the evidence just doesn't show that hydroxychloroquine is effective right now".

https://www.politico.com/news/2020/08/02/trump-health-official-hydroxychloroquine-390601SHITLIBS WILL DO ANYTHING TO QUASH A MIRACLE DRUG FOR A NON-EXISTENT PANDEMIC, THE TRUMP ADMINISTRATION HAS OBVIOUSLY BEEN GOTTEN TO BY THE OLIGARCHY.

[boutons_deux]

"Gilead is at it again.

Back in March — following pressure from Public Citizen and others — the pharmaceutical giant backed down from an immoral scheme to expand its monopoly on remdesivir as the medication began showing promise as a possible treatment for COVID-19.

Now, Public Citizen is revealing that Gilead — along with Donald Trump’s Department of Health and Human Services — has been all but ignoring a similar drug, GS-441524, that may be a better option.

Why would Big Pharma and the Trump administration sit on GS-441524 while aggressively pursuing remdesivir?

Neither the company nor Trump is saying.

But we do know this: Gilead’s patent for GS-441524 expires many years before its patent for remdesivir.

In other words, remdesivir could be far more profitable for the company — even if it turns out to be less effective at helping peoplsurvive the coronavirus."


-- Public Citizen email

[boutons_deux]

As Trump Praises Plasma, Researchers Struggle to Finish Critical Studies

Thousands of Covid-19 patients have been treated with blood plasma outside of rigorous clinical trials —

hampering research that would have shown whether the therapy worked.

https://www.nytimes.com/2020/08/04/health/blood-plasma-covid-19.html

[DarrinS]

As Trump Praises Plasma, Researchers Struggle to Finish Critical Studies

Thousands of Covid-19 patients have been treated with blood plasma outside of rigorous clinical trials —

hampering research that would have shown whether the therapy worked.

https://www.nytimes.com/2020/08/04/health/blood-plasma-covid-19.html






We're all gonna die, bouts. Better hide under your bed with n95. Say hello to chump.

[Winehole23]

We're all gonna die, bouts. Better hide under your bed with n95. Say hello to chump.It's pretty gruesome already, wouldn't you agree?

[ChumpDumper]

We're all gonna die, bouts. Better hide under your bed with n95. Say hello to chump.rent free

[ducks]

Gov. Newsom Says Calif. Weekly Covid-19 Case Average Decreasing

[ChumpDumper]

It's pretty gruesome already, wouldn't you agree?160k dead and all he cares about is whether it affects his 401k.

[ducks]

160k dead and all he cares about is whether it affects his 401k.

Can not buy food you die!

[ChumpDumper]

Can not buy food you die!That's why Trump and the Republicans are stalling the COVID relief bill.

[Winehole23]

Can not buy food you die!Well, there is dumpster diving and stealing and panhandling and breaking a big bill at an ice cream parlor on the Riverwalk with a 15 year old behind the cash register...

Never underestimate the cunning of the impecunious.

[ducks]

Nancy is stalling

[ChumpDumper]

Nancy is stalling
Nancy got her bill passed in May.

[clambake]

You are a Nancy

[Winehole23]

Nancy got her bill passed in May.
Not caving to Republicans is called stalling.

[clambake]

Hey ducks, make sure you do something big.....or you won’t be noticed.

[Winehole23]

this is a preprint


To determine the effect of COVID-19 convalescent plasma on mortality, we aggregated patient outcome data from randomized clinical trials, matched control, and case-series studies. Fixed-effects analyses demontrated that hospitalized COVID-19 patients transfused with convalescent plasma exhibited a ã57% reduction in mortality rate (13%) compared to matched-patients receiving standard treatments (25%; OR: 0.43, P < 0.001). These data provide evidence favouring the efficacy of human convalescent plasma as a therapeutic agent in hospitalized COVID-19 patients.https://onlinelibrary.wiley.com/doi/10.1111/odi.13378

[ducks]

Not caving to Republicans is called stalling.

"It's impossible to make progress when the only position on the table is, 'Pass Speaker Pelosi's bill or nothing.'"

Senator John Kennedy blamed Democrats for the lack of progress on a new coronavirus stimulus bill during an interview on "The Story." The senator also said Republicans will unveil another bill on Wednesday that would extend unemployment compensation benefits. https://fxn.ws/31eT2Ni

[pgardn]

"It's impossible to make progress when the only position on the table is, 'It's got to be approved by Mitch.'"

i (https://fxn.ws/31eT2Ni)

Cmon ducks, this is way too easy.
Do better if you quote Fox.

Again the red team has no concept of hypocrisy.
The basic idea "I can do this but you can't" is much easier.

[Winehole23]

this is the weird situation where Mitch has only about half of the caucus in his pocket. if the Dems don't flex now they may not get another such chance.

[Winehole23]

COVID-19 sniffer dogs in the UAE

https://thepointsguy.co.uk/news/k9s-against-coronavirus-the-uae-implements-sniffer-dogs-to-detect-covid-19/ (https://thepointsguy.co.uk/news/k9s-against-coronavirus-the-uae-implements-sniffer-dogs-to-detect-covid-19/?utm_term=editorial&utm_campaign=facebook&utm_content=F4C597C0-D639-11EA-80EB-45E1923C408C&utm_source=facebook&utm_medium=social)

[Winehole23]

in b4 hamsters and chickens, this is what hypothesizing looks like


AbstractAlthough the benefit of population-level public facial masking to protect others during the COVID-19 pandemic has received a great deal of attention, we discuss for one of the first times the hypothesis that universal masking reduces the “inoculum” or dose of the virus for the mask-wearer, leading to more mild and asymptomatic infection manifestations.

https://link.springer.com/article/10.1007/s11606-020-06067-8#Abs1

[DarrinS]

in b4 hamsters and chickens, this is what hypothesizing looks like

https://link.springer.com/article/10.1007/s11606-020-06067-8#Abs1


From the abstract:

"Asymptomatic infections may be harmful for spread but could actually be beneficial if they lead to higher rates of exposure. Exposing society to SARS-CoV-2 without the unacceptable consequences of severe illness with public masking could lead to greater community-level immunity and slower spread as we await a vaccine."

Totally agree

[Winehole23]

did you notice the "with public masking" part?

[DarrinS]

did you notice the "with public masking" part?

Yes, and...?

[Winehole23]

Yes, and...?I didn't peg you as a pro-mask guy.

[DarrinS]

I didn't peg you as a pro-mask guy.

Well, I am.

[Winehole23]

Well, I am.:tu

[boutons_deux]

Treating the Search for a Covid Vaccine Like an Arms Race Endangers Us All

Vaccine research should not be a national security secret.

http://inthesetimes.com/article/22690/covid-vaccine-arms-race-national-security-world-health-organization-trump/ (http://inthesetimes.com/article/22690/covid-vaccine-arms-race-national-security-world-health-organization-trump/)

[baseline bum]

Looks like we're going to find out pretty quickly if the Oxford vaccine is effective, as they're gathering volunteers to be deliberately infected with SARSCov-2 after getting the vaccine candidate.


https://www.youtube.com/watch?v=FL4F8cKQQhU

[ElNono]

Looks like we're going to find out pretty quickly if the Oxford vaccine is effective, as they're gathering volunteers to be deliberately infected with SARSCov-2 after getting the vaccine candidate.


https://www.youtube.com/watch?v=FL4F8cKQQhU

I'll only get it if it comes with a microchip, tbh

[boutons_deux]

America’s obesity epidemic threatens effectiveness of any COVID vaccine

Scientists know that vaccines

engineered to protect the public from influenza, hepatitis B, tetanus and rabies

can be less effective in obese adults than in the general population,

leaving them more vulnerable to infection and illness.

There is little reason to believe, obesity researchers say, that COVID-19 vaccines will be any different.

https://www.rawstory.com/2020/08/americas-obesity-epidemic-threatens-effectiveness-of-any-vaccine/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29

[Blake]

I'll only get it if it comes with a microchip, tbh

The kind with 5G technology

[Winehole23]

"AeroNabs" uses nanobodies to interfere with the spike protein


To find effective candidates, the scientists parsed a recently developed library in Manglik’s lab of over 2 billion synthetic nanobodies. After successive rounds of testing, during which they imposed increasingly stringent criteria to eliminate weak or ineffective candidates, the scientists ended up with 21 nanobodies that prevented a modified form of spike from interacting with ACE2.

Further experiments, including the use of cryo-electron microscopy (https://www.youtube.com/watch?v=Qq8DO-4BnIY) to visualize the nanobody-spike interface, showed that the most potent nanobodies blocked spike-ACE2 interactions by strongly attaching themselves directly to the spike RBDs. These nanobodies function a bit like a sheath that covers the RBD “key” and prevents it from being inserted into an ACE2 “lock.”



In a final set of experiments, the researchers put the three-part nanobodies through a series of stress tests, subjecting them to high temperatures, turning them into a shelf-stable powder, and making an aerosol. Each of these processes is highly damaging to most proteins, but the scientists confirmed that, thanks to the inherent stability of nanobodies, there was no loss of antiviral potency in the aerosolized form, suggesting that AeroNabs are a potent SARS-CoV-2 antiviral that could be practical to administer via a shelf-stable inhaler or nasal spray.https://www.ucsf.edu/news/2020/08/418241/aeronabs-promise-powerful-inhalable-protection-against-covid-19

[Winehole23]

Sounds too good to be true. The article reads somewhat like a press release, fingers crossed,.

[boutons_deux]

I always expected bio-nano-tech would offer solutions to all kinds of human diseases.

But how can they be sure the nano-bodies for C19 spikes don't lock into someplace else, like cross blood-brain barrier, hormonal disruption?

And what about dosage?

[boutons_deux]

Experts Predict What Life Will Be Like After A COVID-19 Vaccine Arrives

https://www.huffpost.com/entry/life-after-covid-19-vaccine_l_5f2ad9c6c5b64d7a55ed7b2c?ncid=APPLENEWS0 0001

[Winehole23]

I always expected bio-nano-tech would offer solutions to all kinds of human diseases.

But how can they be sure the nano-bodies for C19 spikes don't lock into someplace else, like cross blood-brain barrier, hormonal disruption?

And what about dosage?The effective dose is said to be "small" in the article, but I have no idea what that means. I would imagine clinical trials will take a year or two, unless political pressure shortens the process.

[boutons_deux]

Trump Announces Deal With Moderna for 100 Million Doses of Coronavirus Vaccine
https://www.nationalreview.com/news/coronavirus-trump-announces-deal-with-moderna-for-100-million-doses-covid-19-vaccine/

[Winehole23]

Trump Announces Deal With Moderna for 100 Million Doses of Coronavirus Vaccine


https://www.nationalreview.com/news/coronavirus-trump-announces-deal-with-moderna-for-100-million-doses-covid-19-vaccine/Hope they work and will be safe.

[Winehole23]

monoclonal antibodies


Clinical trials involving a pair of antibodies developed by Regeneron Pharmaceuticals will read out early results in September. A separate effort from Eli Lilly could yield data later in the fall.https://www.statnews.com/2020/08/11/antibody-drugs-could-be-one-of-the-best-weapons-against-covid-19-but-will-they-matter/

[boutons_deux]

Hope they work and will be safe.

deal? meaning Trash is buying 100M to give away free?

or telling Moderna to ramp up for 100M to SELL to us targets for $30?

[Winehole23]

deal? meaning Trash is buying 100M to give away free?

or telling Moderna to ramp up for 100M to SELL to us targets for $30?Dunno, I'd pay 30 bucks for a vaccine that works. Absolutely the cost should be waived for anyone who can't afford it.

Sure, there's probably a grift in there somewhere, but if what results is an effective vaccine it will have been worth it.

[boutons_deux]

I think it was to Moderna that Trash gave $400M for research w/o any diktat on retail price.

Probably same with $Bs Trash has hosed at other BigPharma trying to get a vaccine to announce before the election. Trash doesn't give the tiniest shit about saving lives, only saving his reelection

[boutons_deux]

34 Attorneys General Want Gilead’s Pharma Patent Monopoly on COVID Treatment Remdesivir Busted
https://buzzflash.com/articles/34-attorneys-general-call-to-bust-gileads-pharma-monopoly-on-covid-treatment-remdesivir (https://buzzflash.com/articles/34-attorneys-general-call-to-bust-gileads-pharma-monopoly-on-covid-treatment-remdesivir)

[boutons_deux]

New Nanobodies Block Coronavirus Infection,

Locks Spikes Into 'Inactive' Mode

The preventative nanobodies are even robust enough to become a widely-deployed coronavirus aerosol.

https://interestingengineering.com/new-nanobodies-block-coronavirus-infection-locks-spikes-into-inactive-mode (https://interestingengineering.com/new-nanobodies-block-coronavirus-infection-locks-spikes-into-inactive-mode?utm_source=rss&utm_medium=article&utm_content=13082020)

[pgardn]

Experts Predict What Life Will Be Like After A COVID-19 Vaccine Arrives

https://www.huffpost.com/entry/life-after-covid-19-vaccine_l_5f2ad9c6c5b64d7a55ed7b2c?ncid=APPLENEWS0 0001


The article was interesting but completely whiffed on how drugs other that vaccines may be huge in controlling the symptoms.
And The findings in the ICUs as simple as how to make patients lie on the beds while in care has been very useful as well. Expect a lot more of both.

[pgardn]

New Nanobodies Block Coronavirus Infection,

Locks Spikes Into 'Inactive' Mode

The preventative nanobodies are even robust enough to become a widely-deployed coronavirus aerosol.

https://interestingengineering.com/new-nanobodies-block-coronavirus-infection-locks-spikes-into-inactive-mode (https://interestingengineering.com/new-nanobodies-block-coronavirus-infection-locks-spikes-into-inactive-mode?utm_source=rss&utm_medium=article&utm_content=13082020)

And possibly, new disinfectants... cool.

[ChumpDumper]

I guess there is a measure of self interest here, but props to this 72 year old for walking the walk.

1293944149498933249

[boutons_deux]

The article was interesting but completely whiffed on how drugs other that vaccines may be huge in controlling the symptoms.
And The findings in the ICUs as simple as how to make patients lie on the beds while in care has been very useful as well. Expect a lot more of both.

survivors from hospitals are pretty fucked up for weeks, months, years, forever

true even for non-hospitalized survivors

controlling the symptoms is a band-aid that may not limit the damage

about 40 asymptomatic people from a cruise ship had C19 lung damage.

[pgardn]

I always expected bio-nano-tech would offer solutions to all kinds of human diseases.

But how can they be sure the nano-bodies for C19 spikes don't lock into someplace else, like cross blood-brain barrier, hormonal disruption?

And what about dosage?

Long way to go.
And we dont unless we see obvious side effects.

Eventually I would expect we have a giant library of all the 3-d structure shape of major biomolecules and drugs, cell surface proteins and the type of environment within the 3-d spot, acidic, basic, hydrophilic, hydrophobic.

Then we could run a computer match to see which fit really well and which dont. Which bind temporarily and leave, which get stuck for longer periods...
My hopeful guess.

[pgardn]

survivors from hospitals are pretty fucked up for weeks, months, years, forever

true even for non-hospitalized survivors

controlling the symptoms is a band-aid they may not limit the damage

You dont know that yet. I say we are going to get on top of this.
And band-aides can be very useful for short periods. If they stop the blood clotting for the period that it is most active within the cacophony of symptoms, we have done a good job. This virus staying with us is not the same as the virus producing the awful symptoms we see in some people right now.

I am a natural optimist on almost everything so... yeah.
But this is something that makes much more sense to me to be optimistic about.

You need to vote btw... It matters, even in Texas. People need to see a shift in election numbers to believe.

[tholdren]

You dont know that yet. I say we are going to get on top of this.
And band-aides can be very useful for short periods. If they stop the blood clotting for the period that it is most active within the cacophony of symptoms, we have done a good job. This virus staying with us is not the same as the virus producing the awful symptoms we see in some people right now.

I am a natural optimist on almost everything so... yeah.
But this is something that makes much more sense to me to be optimistic about.

You need to vote btw... It matters, even in Texas. People need to see a shift in election numbers to believe.

Pgardn with that election science to fix covid.


Lololool

Your math

[pgardn]

https://apple.news/A5ZU-h3jVQDayqJ8Z4jCmpQ

very nice summary and good explanations concerning the types of vaccines

definitely not for the foldren.
Requires ability to read and counting to four.

[Blake]

I guess there is a measure of self interest here, but props to this 72 year old for walking the walk.

1293944149498933249

Guess he finally realized this mask was ineffective in several different ways

https://nyc3.digitaloceanspaces.com/theatrenerds-cdn/2016/12/1259947873_1259947873-phantomoftheopera.jpg

[Winehole23]

serial pump and dump


Oleandrin, the experimental extract, was presented to the president in July during an Oval Office meeting and has been touted by Housing and Urban Development Secretary Ben Carson, as well as MyPillow CEO Mike Lindell. Lindell is a key Trump supporter who recently invested in the company producing the unproven extract. “The involvement of the Secretary of HUD and MyPillow.com in pushing a dubious product at the highest levels should give Americans no comfort at night about their health and safety during a raging pandemic,” a senior administration official said. https://www.thedailybeast.com/trump-pushing-new-unproven-plant-extract-as-covid-19-treatment-report?amp=1

[Winehole23]

To the alarm of some government health officials, President Trump has expressed enthusiasm for the Food and Drug Administration to approve an extract from the oleander plant as a dietary supplement to cure COVID-19, despite lack of proof that it works.



The experimental botanical extract, oleandrin, was promoted to Trump during an Oval Office meeting in July.
It's embraced by Housing and Urban Development Secretary Ben Carson and MyPillow founder and CEO Mike Lindell (https://www.mypillow.com/mikes-story), a big Trump backer, who recently took a financial stake in the company that develops the product.
Lindell told Axios that in the meeting, Trump "basically said: …'The FDA should be approving it.'"​
The White House did not respond to requests for comment.

https://www.axios.com/newsletters/axios-sneak-peek-e47f79a5-96aa-4931-9856-34d9fefec0c3.html

[boutons_deux]

Federal Study of Covid Treatments Enters a New Phase

A clinical trial showed that remdesivir helped hospitalized patients.

Now researchers are asking whether when the drug is paired with another antiviral drug, patients will recover faster.

https://www.nytimes.com/2020/08/18/health/Covid-treatments-remdesivir.html

[boutons_deux]

The Pillow Man is pushing plant extract Leandrin, and now he has Trash pushing it, too

Blind leading the ignorant blind

[tholdren]

https://apple.news/A5ZU-h3jVQDayqJ8Z4jCmpQ

very nice summary and good explanations concerning the types of vaccines

definitely not for the foldren.
Requires ability to read and counting to four.

lololol ifr. Just like I said 6 months ago

[ElNono]

lololol ifr. Just like I said 6 months ago

Gossip

[tholdren]

Gossip

nope cdc released data.

[ElNono]

nope cdc released data.

more gossip and a lie...

6 months ago you were buried in your batcave after predicting 10k deaths... lololololololol

[tholdren]

more gossip and a lie...

6 months ago you were buried in your batcave after predicting 10k deaths... lololololololol

Bwhahahahahahhaha el nono deflection and chasing me around. Man getting triggered by me really cut into your spurstalk cred. You and ChumpDumper both. Months of being wrong and mad about it


Lolololllolollll

Not dangerous

[ElNono]

Bwhahahahahahhaha el nono deflection and chasing me around. Man getting triggered by me really cut into your spurstalk cred. You and ChumpDumper both. Months of being wrong and mad about it

Lolololllolollll

Not dangerous


more gossip and a lie...

6 months ago you were buried in your batcave after predicting 10k deaths... lololololololol

:lmao:lmao:lmao

[tholdren]

El nono going all in. BeahahhahahhahahahhahahHa

[ElNono]

6 months ago you were buried in your batcave after predicting 10k deaths... lololololololol

:rollin:rollin:rollin

[Ef-man]

:rollin:rollin:rollin

LOL

Leave him alone Nono, he is obviously bipolar. Just put him on ignore.

[tholdren]

LOL

Leave him alone Nono, he is obviously bipolar. Just put him on ignore.

lolI'll lolol

Too late. El nono wrong about covid. And angry about it for months. Bwjabababbabababbabaahahahhahaha

[Ef-man]

B I P O L A R

[tholdren]

B I P O L A R

beahahahhahahahahahhahahahahahahah

Trying to call names to get out of the lees than flu ifr.



Bwahahahhahahahhahahahahahhahahahahahhajajsjsjsjaj sjsjj


TriggerD

[ElNono]

LOL

Leave him alone Nono, he is obviously bipolar. Just put him on ignore.

lol don't give him an out, he's just as stupid as he sounds...

[ChumpDumper]

more gossip and a lie...

6 months ago you were buried in your batcave after predicting 10k deaths... lololololololol:lmao

[pgardn]

How did he live 60 years without a brain...
I don’t get it.

[Winehole23]

Trump badgers DEEP STATE FDA, or whoever, accusing it of delaying therapies and vaccines.

1297138862108663808

[Winehole23]

snap reaction from drug makers


“Politics must stay out of the conduct and interpretation of clinical trials aimed at evaluating the efficacy and safety of Covid vaccines, as public trust in the results is paramount to ending the pandemic,” John Maraganore, the chief executive of Alnylam Pharmaceuticals, told STAT.

Jeremy Levin, chairman of BIO, the biotechnology industry lobbying group, said, “Developing those critical medicines depends on the independent rigorous reviews, integrity and scientific and medical capability of the FDA. The FDA has assisted and supported the industry to become what it has, and is deeply respected in the USA and abroad.”

BIO emphasized in a statement that the industry “can only move as fast as the science allows us.”

“We are confident everyone is moving as fast as possible to ensure any vaccine or new therapy is both safe and effective for patients to use,” said Rich Masters, BIO’s executive vice president for public affairs.

https://www.statnews.com/2020/08/22/drug-makers-rebut-trump-tweet-that-fda-deep-state-delaying-covid19-vaccines-drugs/

[spurraider21]

Trump badgers DEEP STATE FDA, or whoever, accusing it of delaying therapies and vaccines.

1297138862108663808
Deep state is just anyone in government he doesn’t like.

its like how derp calls everything he doesn’t like fascism or communism

[hater]

"Or whoever" :lmao

Lazy attempt from Drump

[Winehole23]

Fauci interviewed in Der Spiegel

https://www.spiegel.de/international/world/anthony-fauci-helpless-means-you-can-t-do-anyting-there-s-a-lot-we-can-do-a-211cdaf5-d0b1-41f4-b62c-25b76f4d8828

[boutons_deux]

https://scontent-dfw5-2.xx.fbcdn.net/v/t1.0-0/s640x640/118042836_2734007860255855_1113968950434737008_o.j pg?_nc_cat=104&_nc_sid=825194&_nc_ohc=hTkzwwIoMc4AX9D54xz&_nc_oc=AQluNcLdlbZgdVNpsA0xkQiOfAY5sCUIH3_-dINU8Na0OC7GyWK56e0nT_j1_sxuT5c&_nc_ht=scontent-dfw5-2.xx&_nc_tp=7&oh=e4624561a7d33e621d0ac3dfdc08bb34&oe=5F66D12D

[Winehole23]

Deep state is just anyone in government he doesn’t like.

its like how derp calls everything he doesn’t like fascism or communismPeter Navarro has big dingbat energy

1297644730143080450

[Winehole23]

https://www.statnews.com/2020/08/23/fda-under-pressure-from-trump-expected-to-authorize-blood-plasma-as-covid-19-treatment/

[TSA]

Low-dose Hydroxychloroquine Therapy and Mortality in Hospitalized Patients with COVID-19: A Nationwide Observational Study of 8075 Participants

Background

Hydroxychloroquine (HCQ) has been largely used and investigated as therapy of COVID-19 across various settings, at total dose usually ranging from 2400 mg to 9600 mg. In Belgium, off-label use of low-dose HCQ (2400 mg in total over five days) was recommended for hospitalized patients with COVID-19.

Methods

We conducted a retrospective analysis of in-hospital mortality in the Belgian national COVID-19 hospital surveillance data. Patients treated either with HCQ alone and supportive care (HCQ group) were compared to patients treated with supportive care only (no-HCQ group) using a competing risks proportional hazards regression with discharge alive as competing risk, adjusted for demographic and clinical features with robust standard errors.

Results

Of 8075 patients with complete discharge data on 24th of May and diagnosed before the 1st of May, 4542 received HCQ in monotherapy and 3533 were in the no-HCQ group. Death was reported in 804/4542 (17.7%) and 957/3533 (27.1%), respectively. In the multivariable analysis, the mortality was lower in the HCQ group compared to the no-HCQ group (adjusted hazard ratio [HR] 0.684, 95% confidence interval [CI] 0.617–0.758). Compared to the no-HCQ group, mortality in the HCQ group was reduced both in patients diagnosed ≤ 5 days (n=3975) and > 5 days (n=3487) after symptom onset (adjusted HR 0.701, 95% CI 0.617–0.796 and adjusted HR 0.647, 95% CI 0.525–0.797, respectively).

Conclusions

Compared to supportive care only, low-dose HCQ monotherapy was independently associated with lower mortality in hospitalized patients with COVID-19 diagnosed and treated early or later after symptom onset.

https://www.sciencedirect.com/science/article/pii/S0924857920303423?via%3Dihub

[ElNono]

Low-dose Hydroxychloroquine Therapy and Mortality in Hospitalized Patients with COVID-19: A Nationwide Observational Study of 8075 Participants

Background

Hydroxychloroquine (HCQ) has been largely used and investigated as therapy of COVID-19 across various settings, at total dose usually ranging from 2400 mg to 9600 mg. In Belgium, off-label use of low-dose HCQ (2400 mg in total over five days) was recommended for hospitalized patients with COVID-19.

Methods

We conducted a retrospective analysis of in-hospital mortality in the Belgian national COVID-19 hospital surveillance data. Patients treated either with HCQ alone and supportive care (HCQ group) were compared to patients treated with supportive care only (no-HCQ group) using a competing risks proportional hazards regression with discharge alive as competing risk, adjusted for demographic and clinical features with robust standard errors.

Results

Of 8075 patients with complete discharge data on 24th of May and diagnosed before the 1st of May, 4542 received HCQ in monotherapy and 3533 were in the no-HCQ group. Death was reported in 804/4542 (17.7%) and 957/3533 (27.1%), respectively. In the multivariable analysis, the mortality was lower in the HCQ group compared to the no-HCQ group (adjusted hazard ratio [HR] 0.684, 95% confidence interval [CI] 0.617–0.758). Compared to the no-HCQ group, mortality in the HCQ group was reduced both in patients diagnosed ≤ 5 days (n=3975) and > 5 days (n=3487) after symptom onset (adjusted HR 0.701, 95% CI 0.617–0.796 and adjusted HR 0.647, 95% CI 0.525–0.797, respectively).

Conclusions

Compared to supportive care only, low-dose HCQ monotherapy was independently associated with lower mortality in hospitalized patients with COVID-19 diagnosed and treated early or later after symptom onset.

https://www.sciencedirect.com/science/article/pii/S0924857920303423?via%3Dihub

:tu

Also on the paper, worth pointing out:

Although observational studies, even of large scale, do not provide final conclusions on treatment efficacy, their results are important to consider to guide clinical trials. Well-designed prospective studies combined with large randomized control trials should provide definitive evidence about the clinical impact of HCQ in severe hospitalized and in mild ambulatory COVID-19 patients. Meanwhile, in a preprint publication at the time of writing, the results of the RECOVERY trial did not show any clinical benefit (death or discharge) in the high dose HCQ arm (9200 mg in total over 10 days) compared to usual care in hospitalized COVID-19 patients (median number of days from symptom onset to randomization: 9 days)

[hater]

Peter Navarro has big dingbat energy

1297644730143080450

This n8ga reminds me ofJoseph Goebles tbqh

Hes a horrible human hope he perishes in the immediate future

[tholdren]

lol vaccine

[Winehole23]

storage issues could put a stitch in administering the Moderna and Pfizer vaccines;


Executives from Moderna and Pfizer on Wednesday separately told the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practice on Wednesday that mRNA-1273, which is Moderna’s coronavirus vaccine candidate, requires a storage temperature of negative 4 degrees Fahrenheit. BioNTech and Pfizer’s candidates, BN1162b2 and BNT162b2, need to be stored in negative 94 degrees Fahrenheit.

“These storage conditions would make traditional office or pharmacy administration very difficult,” SVB Leerink analysts wrote in a note to investors on Thursday. “These conditions could be met at tertiary hospitals and laboratories and could be accommodated in intensive one-day vaccination events at such sites, but this would still only cover a fraction of the healthy population.”



Dr. Kathleen Dooling, a medical officer for the agency’s division of viral diseases, said (https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2020-08/COVID-08-Dooling.pdf) Wednesday that storage, distribution, and handling requirements of these vaccines “will make it very difficult for community clinics and local pharmacies to store and administer.” She also noted that most vaccines will have to be “administered at centralized sites with adequate equipment and high throughput.”

Pfizer will need to use ultralow temperature freezers and thermal shipper storage for its COVID-19 vaccine candidates, according to comments made by Dr. Nicholas Kitchin, senior director of Pfizer’s vaccine clinical research and development group.

https://www.marketwatch.com/story/moderna-and-pfizers-covid-19-vaccine-candidates-require-ultra-low-temperatures-raising-questions-about-storage-distribution-2020-08-27

[Splits]

Another risky, shitty decision


U.S. says it won’t join WHO-linked effort to develop, distribute coronavirus vaccine
...

The Covax decision, which has not been previously reported, is effectively a doubling down by the administration on its bet that the United States will win the vaccine race (https://www.washingtonpost.com/graphics/2020/health/covid-vaccine-update-coronavirus/?itid=ap_carolyny.%20johnson&itid=lk_inline_manual_11). It eliminates the chance to secure doses from a pool of promising vaccine candidates — a potentially risky strategy.

“America is taking a huge gamble by taking a go-it-alone strategy,” said Lawrence Gostin, a professor of global health law at Georgetown University.

Kendall Hoyt, an assistant professor at Dartmouth’s Geisel School of Medicine, said it was akin to opting out of an insurance policy.

The United States could be pursuing bilateral deals with drug companies and simultaneously participating in Covax, she said, increasing its odds of getting some doses of the first safe vaccine. “Just from a simple risk management perspective, this [Covax decision] is shortsighted, she said.

The U.S. move will also shape what happens elsewhere. The idea behind Covax is to discourage hoarding and focus on vaccinating high-risk people in every country first, a strategy that could lead to better health outcomes and lower costs, experts said.



https://www.washingtonpost.com/world/coronavirus-vaccine-trump/2020/09/01/b44b42be-e965-11ea-bf44-0d31c85838a5_story.html

[BSfromTX]

Why would you want a vaccine for something that has a 99.96% survival rate? Assuming the numbers are even correct.

AND why would the U.S. want to take medical guidance from an international bureaucracy? How can we know that they represent our best interests? Most in here don't even trust our own president.

[Winehole23]

Vaccines are desirable because the conditions of COVID-19 morbidity are perfectly serious too. Lung damage, heart damage, kidney damage, strokes, other lingering respiratory, neurological and psychological issues, etc..

Heart damage has been detected in up to 50% of patients withonly mild symptoms or none at all.

Vaccines are also desirable because they're the safest path to herd immunity. If we tried to get there without non-medical countermeasures, theraputics and vaccines, about 2 million Americans could die in one year, according to some of the models.

[boutons_deux]

Why would you want a vaccine for something that has a 99.96% survival rate? Assuming the numbers are even correct.

AND why would the U.S. want to take medical guidance from an international bureaucracy? How can we know that they represent our best interests? Most in here don't even trust our own president.

USA's CFR is about 3%, not your .04%

your rightwingnutjobs never get your shit straight, live in a bubble of ignorant fantasy

[boutons_deux]

Stem Cell Trial Tests Treatment For Often-Fatal COVID-19 Lung Damage

https://scienceblog.com/518240/stem-cell-trial-tests-treatment-for-often-fatal-covid-19-lung-damage (https://scienceblog.com/518240/stem-cell-trial-tests-treatment-for-often-fatal-covid-19-lung-damage/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+scienceblogrssfeed+%28Science Blog.com%29)

[Ef-man]

USA's CFR is about 3%, not your .04%

your rightwingnutjobs never get your shit straight, live in a bubble of ignorant fantasy

Boutons, dont waste your time trying to educate someone that cant even spell G.E.D.

He is an obvious future Darwin Award winner.

[BSfromTX]

Boutons, dont waste your time trying to educate someone that cant even spell G.E.D.

He is an obvious future Darwin Award winner.

So how will you decide on getting vaccinated? How will you decide on efficacy and safety?
Will you study up on it yourself? Trust big pharma? Wait for the Democrats’ vaccine?

I am all ears as to what your knowledge on the subject is. Don’t give me links. Tell me in your words what you understand about epidemiology, virology, genetics, immunology, respiratory diseases, etc..

[DarrinS]

USA's CFR is about 3%, not your .04%

your rightwingnutjobs never get your shit straight, live in a bubble of ignorant fantasy

CFR >> IFR

[Ef-man]

So how will you decide on getting vaccinated? How will you decide on efficacy and safety?
Will you study up on it yourself? Trust big pharma? Wait for the Democrats’ vaccine?

I am all ears as to what your knowledge on the subject is. Don’t give me links. Tell me in your words what you understand about epidemiology, virology, genetics, immunology, respiratory diseases, etc..

You dont believe Boutons so I do not expect you to believe me either. Further, throwing out this international bureaucracy obscure reference and believing trump has me concerned with your mental health.

But to make it easy for others, speak with your general practitioner, go over your medical history, and do as they recommend. If you get vaccine, one month after first vaccine shot, you will get second vaccine booster. Do not over think it. Just like getting vaccine for MMR, tetanus, Pneumonia, Shingles, etc.

[BSfromTX]

You dont believe Boutons so I do not expect you to believe me either. Further, throwing out this international bureaucracy obscure reference and believing trump has me concerned with your mental health.

But to make it easy for others, speak with your general practitioner, go over your medical history, and do as they recommend. If you get vaccine, one month after first vaccine shot, you will get second vaccine booster. Do not over think it. Just like getting vaccine for MMR, tetanus, Pneumonia, Shingles, etc.

i appreciate the civil response. I agree on consulting your physician. The WHO and the CDC are not my personal physicians, so yes I am not sure how much I trust those two institutions...

We may disagree on some points, but I respect yours.

as for trump, I am not a supporter.

as for a vaccine, i would not rush to take a vaccine that has not been thoroughly tested. A vaccine depends on identifying a specific and consistent antigen of the virus that the immune system can recognize and create antibodies for... so, correct me if I am wrong, but there are reports of people getting it twice and that the virus mutates from cell to cell (but how much and at what rate)? These are two critical factors. What are your thoughts on the surface antigens of Covid 19? Like the flu vaccine it is a crap shoot (40% chance) the vaccine is what you will be exposed to. If our immune system may not be successful and the virus is continually changing, what would you suggest is the answer?

[pgardn]

i appreciate the civil response. I agree on consulting your physician. The WHO and the CDC are not my personal physicians, so yes I am not sure how much I trust those two institutions...

We may disagree on some points, but I respect yours.

as for trump, I am not a supporter.

as for a vaccine, i would not rush to take a vaccine that has not been thoroughly tested. A vaccine depends on identifying a specific and consistent antigen of the virus that the immune system can recognize and create antibodies for... so, correct me if I am wrong, but there are reports of people getting it twice and that the virus mutates from cell to cell (but how much and at what rate)? These are two critical factors. What are your thoughts on the surface antigens of Covid 19? Like the flu vaccine it is a crap shoot (40% chance) the vaccine is what you will be exposed to. If our immune system may not be successful and the virus is continually changing, what would you suggest is the answer?

This vaccine has a much better chance of being effective compared to the flu vaccine. And the flu vaccine, even if not stopping the flu, usually greatly reduces the symptoms. People just dont understand vaccines. Not only that, getting a flu vaccine also means you have a greater probability of NOT GIVING THE FLU to someone ELSE.

I have never had the flu, even before the vaccine. I still get vaccinated because I WORK around other people in close proxomity that do not need to get the bad symptoms (that I DONT get) and then give the flu to their parents or kids. This is real herd immunity, because we have a vaccine. You rely on people like me not to give it to you basically.
I thank you.

[DarrinS]

Half of the population already immune to Chinese lung AIDS.

Give the vaccine to the vulnerable.

[Winehole23]

Half of the population already immune to Chinese lung AIDS.

Give the vaccine to the vulnerable.Why not to everyone so they don't get sick?

Vaccines are the royal road to herd immunity. Mitigates harm as well as morbidity.

[ChumpDumper]

Half of the population already immune to Chinese lung AIDS.Why do you lie?

[Winehole23]

Preventing death is the soda straw view. So many other bad things can happen.

[DarrinS]

Why not to everyone so they don't get sick?

Vaccines are the royal road to herd immunity. Mitigates harm as well as morbidity.


There is actually a protocol for who gets a vaccine first. Look that up.

[pgardn]

There is actually a protocol for who gets a vaccine first. Look that up.

It would be nice to have a working vaccine fully tested.
We dont yet.

[DarrinS]

Preventing death is the soda straw view. So many other bad things can happen.


Muh soda straw analogy.

[pgardn]

There is actually a protocol for who gets a vaccine first. Look that up.

Do you know why there is a list?
Hint... There is no rush for a flu vaccine.

[DarrinS]

It would be nice to have a working vaccine fully tested.
We dont yet.

Well, yeah, that's pretty important.

[DarrinS]

Do you know why there is a list?

Yes

[Winehole23]

There is actually a protocol for who gets a vaccine first. Look that up.at first , of course.

Do you assume we'll never have enough for everyone?

7

[pgardn]

Yes

So why did you respond to Winehole the way did?

[pgardn]

I honestly wish one of the symptoms of this disease was mild facial disfiguration and everyone got this symptom.
Then it might be taken seriously.

[DarrinS]

I'd be in the last group to get it, so I really don't care at that point.

[DarrinS]

I honestly wish one of the symptoms of this disease was mild facial disfiguration and everyone got this symptom.
Then it might be taken seriously.


It's serious for a very small demographic.

[ChumpDumper]

It's serious for a very small demographic.How did that get to be 200,000 dead?

[pgardn]

It's serious for a very small demographic.

I think you get my point.
People were literally fighting over the vaccination for small pox because they did not want the horrible face disfuguration that was a widespread symptom if you lived through it.

[DarrinS]

I think you get my point.
People were literally fighting over the vaccination for small pox because they did not want the horrible face disfuguration that was a widespread symptom if you lived through it.

This ain't smallpox bro

This is a Nothingburger for vast vast majority. Old and multiple health problems? Different story

[ChumpDumper]

This ain't smallpox bro

This is a Nothingburger for vast vast majority. Old and multiple health problems? Different storyWhy are ~200,000 dead?

[baseline bum]

This ain't smallpox bro

This is a Nothingburger for vast vast majority. Old and multiple health problems? Different story

Fuck you calling this a nothingburger

[DarrinS]

Fuck you calling this a nothingburger

Alrighty then

[DarrinS]

https://www.statnews.com/2020/09/01/u-s-advisory-group-lays-out-detailed-recommendations-on-how-to-prioritize-covid-19-vaccine/?ocid=uxbndlbing

[baseline bum]

Alrighty then

Die in a fire faggot

[ChumpDumper]

It's important we don't normalize Karrinish behavior.:tu

[DarrinS]

Die in a fire faggot

Not gonna happen. Anything else?

[pgardn]

This ain't smallpox bro

This is a Nothingburger for vast vast majority. Old and multiple health problems? Different story

If it killed no one bro, but caused facial disfigurement, people would be lining up, bro...

[DarrinS]

If it killed no one bro, but caused facial disfigurement, people would be lining up, bro...

Uh, ok

[ChumpDumper]

:lol Karrin tried to say "bro" unironically

[Winehole23]

Muh soda straw analogy.
Bartleby the Scrivener dead wall reverie.

For some inexplicable reason you prefer that.

Chacun a son goût.

[baseline bum]

Why are ~200,000 dead?

They don't matter, they're not in that piece of shit's zipcode

[DarrinS]

It's odd that the 24/7 dead enders think I can see their posts. :lmao

[DarrinS]

They don't matter, they're not in that piece of shit's zipcode

Zing

[Ef-man]

Ditto pgardn.

It is up to everyone who can get it to protect at risk people, minimize covid effects on ones health or prevent death, prevent spreading covid.

As pgardn says, get it if your general practice says you can receive the vaccine, even though the vaccine may or may not be 100% perfect, it will have positive effects.

Thank you pgardn!

[ChumpDumper]

It's odd that the 24/7 dead enders think I can see their posts. :lmaoAs long as someone you read is calling you a piece of shit, it's fine with me.:tu

[DarrinS]

This disease got who it was going to get. It will fade fast now. Get the vaccine if you want. I've already had Chinese lung AIDS, so I'm not concerned.

[pgardn]

Uh, ok

You dont think so apparently.
I disagree.

If this had symptoms that caused permanent facial scaring you would be right in line behind TGY and derp.

[ChumpDumper]

This disease got who it was going to get. It will fade fast now. Get the vaccine if you want. I've already had Chinese lung AIDS, so I'm not concerned.You're simply wrong.

And a piece of shit.

[Winehole23]

It's serious for a very small demographic.the size of the caseload magnifies that demographic.

[Ef-man]

This disease got who it was going to get. It will fade fast now. Get the vaccine if you want. I've already had Chinese lung AIDS, so I'm not concerned.

Reports indicate you can get it again after few months. Hopefully, it will not cause any damage so stay healthy.

[baseline bum]

Zing

It's amazing you had more outrage over Obama taking muh lightbulbs than you do ~200k Americans dead.

[pgardn]

Okay.


Darrin got on a thread about vaccines to say he does not care.
alrighty then...

[baseline bum]

:lmao you stupid motherfuckers have been saying that since February.

Over/under on how many times he'll say the pandemic is almost over?

[Winehole23]

:lmao you stupid motherfuckers have been saying that since February.Flu season coming up. Get yer shot.

[Winehole23]

Over/under on how many times he'll say the pandemic is almost over?According to DarrinS, we've turned the corner. COVID-19 is almost over.

[DarrinS]

Okay.


Darrin got on a thread about vaccines to say he does not care.
alrighty then...


No -- give it to the people that need it. I don't need it for myself.

[pgardn]

Reports indicate you can get it again after few months. Hopefully, it will not cause any damage so stay healthy.

Very few reports from what I have seen.
It looks like with the number of people that have gotten this worldwide, the reinfection is very low.
We wont know for sure for a while but imo this part looks good thankfully.

[baseline bum]

According to DarrinS, we've turned the corner. COVID-19 is almost over.

Just like in May

[DarrinS]

According to DarrinS, we've turned the corner. COVID-19 is almost over.

Some places, yes.

[Winehole23]

Just like in MayPure wishcasting.

[DarrinS]

Very few reports from what I have seen.
It looks like with the number of people that have gotten this worldwide, the reinfection is very low.
We wont know for sure for a while but imo this part looks good thankfully.

Very rational post. :tu

[Winehole23]

Some places, yes.The pandemic is discontinuous, You wouldn't want to be in Iowa or Illinois right now.

[DarrinS]

The pandemic is discontinuous, You wouldn't want to be in Iowa or Illinois right now.

Hence "some places". The timing and geographic location of outbreaks has varied widely.

[Ef-man]

Very few reports from what I have seen.
It looks like with the number of people that have gotten this worldwide, the reinfection is very low.
We wont know for sure for a while but imo this part looks good thankfully.

Knock on wood.

Like you say, too early to positively say one way or another but reinfection has been documented. With high infection rate, US will soon provide more data on this.

[ChumpDumper]

Hence "some places". The timing and geographic location of outbreaks has varied widely.Why didn't it disappear quickly?

[pgardn]

No -- give it to the people that need it. I don't need it for myself.

You did not give me that impression.
I guess you needed a more drastic version of the symptoms.
But Im glad you got off fairly easy. People have died in my zipcode, in my neighborhood... they are gone.

But glad you are well. And so far no one I know personally has died. But they have gotten the shit kicked out of them. One has a pretty bad heart arrhythmia now so we will see. And yes they are older folks. But I have a fondness for them because they are good people who are parents of good friends. And then somehow this kinda transfers to people I dont know, its this strange thing some people feel, empathy. Some call it virtue signaling, or playing the White Knight. Kinda wish I did not have it but its a fcking weakness I guess. fcking Judeo-Christian upbringing maybe... I blame my parents, relatives and friends. yeah Priests and preachers as well...

[Winehole23]

Hence "some places". The timing and geographic location of outbreaks has varied widely.Somewhat unrelated to density or summertime teperatures, apparently.

[ChumpDumper]

Somewhat unrelated to density or summertime teperatures, apparently.Lost count of how many times Karrin moved det goalpost.

[pgardn]

People just dont get this thing is super contagious and NOT a common cold or flu.
These super spreading events happening almost everywhere in the world are vicious little lessons.

[pgardn]

Somewhat unrelated to density or summertime teperatures, apparently.

We hope.
I still dont see how outdoor temp help the virus other than driving people inside together to cool off.
Its still hot as hell and I stay the hell outside when not working. Im drinking water out of a horse trough... its ridiculous how much water Im drinking.

[pgardn]

Flu season coming up. Get yer shot.

Got it.
The quadravalent if possible. Ask for it.

[Ef-man]

Got it.
The quadravalent if possible. Ask for it.

Like my beer drinking at a bar several days before paycheck, I just ask for cheapest thing on tap.

[DarrinS]

You did not give me that impression.
I guess you needed a more drastic version of the symptoms.
But Im glad you got off fairly easy. People have died in my zipcode, in my neighborhood... they are gone.

But glad you are well. And so far no one I know personally has died. But they have gotten the shit kicked out of them. One has a pretty bad heart arrhythmia now so we will see. And yes they are older folks. But I have a fondness for them because they are good people who are parents of good friends. And then somehow this kinda transfers to people I dont know, its this strange thing some people feel, empathy. Some call it virtue signaling, or playing the White Knight. Kinda wish I did not have it but its a fcking weakness I guess. fcking Judeo-Christian upbringing maybe... I blame my parents, relatives and friends. yeah Priests and preachers as well...


I have three relatives in their 70's, including my mom, in SA. They are fine.

I take every precaution around them.

[DarrinS]

People just dont get this thing is super contagious and NOT a common cold or flu.
These super spreading events happening almost everywhere in the world are vicious little lessons.

Flu is worse for some people. Covid worse for others.

[Winehole23]

KarrinS the COVID minimizer.

Always minimizing, no matter the tally or the caseload. Totally indifferent to the magnitude of death, morbidity and suffering in this country.

Half a WWII's worth of death in a little over half a year doesn't phase him.

[DarrinS]

KarrinS the COVID minimizer.

Always minimizing, no matter the tally or the caseload. Totally indifferent to the magnitude of death, morbidity and suffering in this country.

Half a WWII's worth of death in a little over half a year doeisn't phase him.


Do you happen to know how many people died in 2017, just of heart disease and cancer?

Did those deaths phase you?

[DarrinS]

Do you happen to know how many people died in 2017, just of heart disease and cancer?

Did those deaths phase you?

It was over 1M, just so you know.

[ChumpDumper]

Do you happen to know how many people died in 2017, just of heart disease and cancer?

Did those deaths phase you?Comparisons good now.

[ChumpDumper]

It was over 1M, just so you know.You can't give your mother heart disease or cancer.

[Winehole23]

It was over 1M, just so you know.COVID-19 is the third leading cause of death in the USA now, behind heart disease and cancer.

[SnakeBoy]

Somewhat unrelated to density or summertime teperatures, apparently.

There have been a number of studies now linking low humidity to helping the spread. Basically in low humidity the droplets get smaller/lighter and linger in the air longer. Hot/cold weather keep people indoors with ac/heat on, both of which lower humidity.
https://www.sciencedaily.com/releases/2020/08/200820102503.htm

We should see if the theory holds water soon. As the south & west move into pleasant weather and the north/northeast get cold again.

[pgardn]

There have been a number of studies now linking low humidity to helping the spread. Basically in low humidity the droplets get smaller/lighter and linger in the air longer. Hot/cold weather keep people indoors with ac/heat on, both of which lower humidity.
https://www.sciencedaily.com/releases/2020/08/200820102503.htm

We should see if the theory holds water soon. As the south & west move into pleasant weather and the north/northeast get cold again.

this is very interesting I would have thought the opposite.
but it does make sense. these climate scientists who specialize in the size of water droplets and other particulates are becoming very important now. benefits of basic science.

The way droplets move in still air versus moving air is also important. I read one study that said moving air the droplets basically go right around objects. still air you have more of a chance of breathing it in.

[pgardn]

Flu is worse for some people. Covid worse for others.

again it is the contagiousness of this virus that makes it worrisome.
if more people get it, then more people are likely to die from it, it’s quite simple.

this is why I posed the math question to the foldern and he folded.
if everyone in the world gets it and 0.1% die from it, this is not a good thing.
if a virus is spread very selectively less people get it and more people may die from it but in totality because it is selective it kills fewer people. I don’t see why people can’t get this.

and this is not even taking into account the people that survive but have very debilitating symptoms. this is just not in the USA it’s everywhere, except Antarctica. Wait until India’s stats come in I have a feeling it’s going to be awful. They have more ability to move about than the Chinese who adhere to rules very well.

[baseline bum]

There have been a number of studies now linking low humidity to helping the spread. Basically in low humidity the droplets get smaller/lighter and linger in the air longer. Hot/cold weather keep people indoors with ac/heat on, both of which lower humidity.
https://www.sciencedaily.com/releases/2020/08/200820102503.htm

We should see if the theory holds water soon. As the south & west move into pleasant weather and the north/northeast get cold again.

So you're saying the buttfucking San Antonio got in June and July while humidity was through the roof is nothing compared to what this fall and winter will be like? Ouch.

[BSfromTX]

This vaccine has a much better chance of being effective compared to the flu vaccine. And the flu vaccine, even if not stopping the flu, usually greatly reduces the symptoms. People just dont understand vaccines. Not only that, getting a flu vaccine also means you have a greater probability of NOT GIVING THE FLU to someone ELSE.

I have never had the flu, even before the vaccine. I still get vaccinated because I WORK around other people in close proxomity that do not need to get the bad symptoms (that I DONT get) and then give the flu to their parents or kids. This is real herd immunity, because we have a vaccine. You rely on people like me not to give it to you basically.
I thank you.


Correct. Many people do not understand vaccines. It takes a deep understanding of immunology, protein structure and sequence, genetics, virology, epidemiology, and host cell replication. I know some on the subjects, but I won't dare claim to know everything or be an expert unlike many in here. Again, if some have actually gotten the virus twice, that suggests either a failure to develop immunity or enough of a change in antigen representation to get by a second time.
I feel it is very reasonable to question the idea of rushing to take a vaccine for a virus with these characteristics and with such a low death rate.

I don't understand why so many in here get upset by questioning this. At the end of the day we all depend on our personal knowledge which does not take us very far and then we look to medical professionals, media, or worse political positioning. The fundamental difference in here is how much people trust the resources on the internet and which ones. There are plenty of conflicting views in the medical profession to warrant questioning things like this (either way).

I am not anti-vaccine. I just don't think it is wise to play with our systems for viruses that are not much of a threat. I realize that many in here consider it a catastrophic threat, but I politely disagree. I choose not to trust our president, our politicians, the WHO, the CDC, and especially mainstream media. My own physician, whom I respect and trust, does not agree with the masks and social distancing as well as many other physicians I know nor are they chomping at the bit to get a vaccine for it.

I realize that there is disagreement with this, which is at least reason enough to question all sides in the matter. There are many disagreements in the medical field, so what makes us so confident to know what side to be on.

Never had the flu vaccine and have not had the flu in at least 30 years if ever. I appreciate the fact that you feel you are protecting others by getting it, however I am not certain I follow the logic. Your position is that while you may either be immune to the flu or simply never exposed, by having had the vaccine you are protecting others by not being a carrier? It would be nice to know how you come to that conclusion (in your own words please).

[ChumpDumper]

So you're saying the buttfucking San Antonio got in June and July while humidity was through the roof is nothing compared to what this fall and winter will be like? Ouch.Dude, we can open Darrin's bar for that two weeks of good fall weather coming up!

[SnakeBoy]

So you're saying the buttfucking San Antonio got in June and July while humidity was through the roof is nothing compared to what this fall and winter will be like? Ouch.

No. They are saying that hot/cold weather keeps people indoors more where they keep the windows closed and run their AC or heat which keeps the humidity low and accelerates transmission. So if that theory is correct we should see cases reduce here and an increase in cases in colder climate states & Europe. It would explain why the Northeast got fucked at the beginning of the year and we didn't, even though we had community spread in January but it never took off until it got hot.

If it's true then we should start seeing outbreaks shift regions over the next month or two.

[ChumpDumper]

No. They are saying that hot/cold weather keeps people indoors more where they keep the windows closed and run their AC or heat which keeps the humidity low and accelerates transmission. So if that theory is correct we should see cases reduce here and an increase in cases in colder climate states & Europe. It would explain why the Northeast got fucked at the beginning of the year and we didn't, even though we had community spread in January but it never took off until it got hot.

If it's true then we should start seeing outbreaks shift regions over the next month or two.:lol it got off the ground when Darrin's bar opened.

[baseline bum]

No. They are saying that hot/cold weather keeps people indoors more where they keep the windows closed and run their AC or heat which keeps the humidity low and accelerates transmission. So if that theory is correct we should see cases reduce here and an increase in cases in colder climate states & Europe. It would explain why the Northeast got fucked at the beginning of the year and we didn't, even though we had community spread in January but it never took off until it got hot.

If it's true then we should start seeing outbreaks shift regions over the next month or two.

Does AC really bring down humidity that hugely? Maybe late at night I guess when our summer dewpoints can get in the mid to high 70s, but is any AC dropping humidity from daytime dewpoints in the 60s enough to beat out fall when our daytime dewpoints are in the 50s or winter when they can be in the 30s and 40s?

[SnakeBoy]

Does AC really bring down humidity that hugely? Maybe late at night I guess when our summer dewpoints can get in the mid to high 70s, but is any AC dropping humidity from daytime dewpoints in the 60s enough to beat out fall when our daytime dewpoints are in the 50s or winter when they can be in the 30s and 40s?

Yeah that's a good question. The study I linked, which is a study of studies, said "relative humidity of 40 to 60 percent could reduce the spread". I don't think my ac is ever getting humidity below 40% in the summer.

Maybe all these studies should have a little disclaimer saying: Don't ask too many questions, We got paid.

[pgardn]

Correct. Many people do not understand vaccines. It takes a deep understanding of immunology, protein structure and sequence, genetics, virology, epidemiology, and host cell replication. I know some on the subjects, but I won't dare claim to know everything or be an expert unlike many in here. Again, if some have actually gotten the virus twice, that suggests either a failure to develop immunity or enough of a change in antigen representation to get by a second time.
I feel it is very reasonable to question the idea of rushing to take a vaccine for a virus with these characteristics and with such a low death rate.

I don't understand why so many in here get upset by questioning this. At the end of the day we all depend on our personal knowledge which does not take us very far and then we look to medical professionals, media, or worse political positioning. The fundamental difference in here is how much people trust the resources on the internet and which ones. There are plenty of conflicting views in the medical profession to warrant questioning things like this (either way).

I am not anti-vaccine. I just don't think it is wise to play with our systems for viruses that are not much of a threat. I realize that many in here consider it a catastrophic threat, but I politely disagree. I choose not to trust our president, our politicians, the WHO, the CDC, and especially mainstream media. My own physician, whom I respect and trust, does not agree with the masks and social distancing as well as many other physicians I know nor are they chomping at the bit to get a vaccine for it.

I realize that there is disagreement with this, which is at least reason enough to question all sides in the matter. There are many disagreements in the medical field, so what makes us so confident to know what side to be on.

Never had the flu vaccine and have not had the flu in at least 30 years if ever. I appreciate the fact that you feel you are protecting others by getting it, however I am not certain I follow the logic. Your position is that while you may either be immune to the flu or simply never exposed, by having had the vaccine you are protecting others by not being a carrier? It would be nice to know how you come to that conclusion (in your own words please).

by far the highest probability is that I have very mild symptoms for the flu virus.

so I get the vaccine because I am most likely a carrier and because it’s just not that difficult. I don’t fear vaccines like others because I’ve gotten vaccines for getting into school etc. as a youngster and never had a problem.
there are clearly people who react badly to vaccines and they know this because they have been vaccinated. my take is you have an anti-VAX stand.

If you went to public school in the US you have a high probability of already being vaccinated. People go in for tetanus vaccines all the time for boosters. People willingly vaccinate their precious pets. Then they claim they refuse to get vaccinated because they are putting shit into their body which they have already done before and done to their pets.

seems extraordinarily insincere or highly paranoid.

[SnakeBoy]

I just don't think it is wise to play with our systems for viruses that are not much of a threat.

What is it about the flu vaccine that scares you? I mean what do you think might happen to you if you get it?

[ElNono]

What is it about the flu vaccine that scares you? I mean what do you think might happen to you if you get it?

Antibodies might follow you around... serious stuff.

[BSfromTX]

What is it about the flu vaccine that scares you? I mean what do you think might happen to you if you get it?

I would rather develop an immunity naturally and I really don’t care to take the vaccine (possibly get sick like some do anyway) and then still have a chance to contract other strains. I feel most vaccines are well intended and beneficial, but the flu just isn’t enough of a threat to me to consider.

what seems to bother me the most is the relentless recommendation to get it by government officials. I’m sorry, but I don’t feel like the government cares that much about our well being. I also don’t understand why decisions like mine are so bothersome and/or offensive to others

[pgardn]

I would rather develop an immunity naturally and I really don’t care to take the vaccine (possibly get sick like some do anyway) and then still have a chance to contract other strains. I feel most vaccines are well intended and beneficial, but the flu just isn’t enough of a threat to me to consider.

what seems to bother me the most is the relentless recommendation to get it by government officials. I’m sorry, but I don’t feel like the government cares that much about our well being. I also don’t understand why decisions like mine are so bothersome and/or offensive to others

I actually dont care a bit as long as I know you will not pass it on to someone else.
There are people who cannot take the vaccine who might be extraordinarily vulnerable to the flu as well.

As far as the government and your vs. the people's best interest, thats a whole other topic.
And then flat out believing the government does not have the rights and best interest of the individual AND the whole of society.... another discussion again.
If the sentence above is true, then personally, I would leave the country. And do work on the outside to re enter it. A revolution is in order.

[Ef-man]

I would rather develop an immunity naturally and I really don’t care to take the vaccine (possibly get sick like some do anyway) and then still have a chance to contract other strains. I feel most vaccines are well intended and beneficial, but the flu just isn’t enough of a threat to me to consider.

what seems to bother me the most is the relentless recommendation to get it by government officials. I’m sorry, but I don’t feel like the government cares that much about our well being. I also don’t understand why decisions like mine are so bothersome and/or offensive to others

Try developing natural immunity to polio.

Tell us how that goes.

[pgardn]

Does AC really bring down humidity that hugely? Maybe late at night I guess when our summer dewpoints can get in the mid to high 70s, but is any AC dropping humidity from daytime dewpoints in the 60s enough to beat out fall when our daytime dewpoints are in the 50s or winter when they can be in the 30s and 40s?

My experience is that AC does indeed decrease the humidity but more so in the summer. Colder air cant hold as much water as warm air in general although you can get dry warm fronts and wet cold fronts depending if they come off the middle of a continent or off the ocean. And how much water they gain or lose as they move.
Thats why very dry cold fronts we expect to come in the fall are incredibly welcome. In Colorado, the humidity gets so low at altitude and cold air that its clearly time for lip balms. I never need this in San Antonio.

Also static electricity is a hell of a lot of fun to play with when a cold front comes through.
Wax up the car, drive really fast for a while through the dry air, stop at a gate that requires you press metal buttons, and zap. Much better than socks on a rug.
Turning the lights off with a polymer type sheet after it has been through the dryer is really neat to watch all the little blue sparks zapping around on a dry night.
The wife and I do it regularly during cold fronts.

[BSfromTX]

Try developing natural immunity to polio.

Tell us how that goes.

I don’t recall stating the polio vaccine is not beneficial.

[Ef-man]

I don’t recall stating the polio vaccine is not beneficial.

It wont necessarily kill you and many people fully recover.

Same with covid.

[baseline bum]

My experience is that AC does indeed decrease the humidity but more so in the summer. Colder air cant hold as much water as warm air in general although you can get dry warm fronts and wet cold fronts depending if they come off the middle of a continent or off the ocean. And how much water they gain or lose as they move.


Maybe on extremely humid days like today in San Antonio where the dew point was in the 70s all day, but that's pretty unusual and normally it's in the 60s or even high 50s in summer days. No one is cooling his house to 60-65 in the summer in San Antonio so you're not hitting that dew point where the air would have no ability to hold any more water.

[pgardn]

Maybe on extremely humid days like today in San Antonio where the dew point was in the 70s all day, but that's pretty unusual and normally it's in the 60s or even high 50s in summer days. No one is cooling his house to 60-65 in the summer in San Antonio so you're not hitting that dew point where the air would have no ability to hold any more water.

This is true. When I say decrease more I mean the humidity would drop more overall, but no way it gets around to the low levels like we get with a cold front.

[boutons_deux]

A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged

A closer look at the Bradykinin hypothesis


The computer had revealed a new theory about how Covid-19 impacts the body:

the bradykinin hypothesis (https://www.the-scientist.com/news-opinion/is-a-bradykinin-storm-brewing-in-covid-19--67876).

The hypothesis provides a model that explains many aspects of Covid-19,

including some of its most bizarre symptoms (https://elemental.medium.com/every-covid-19-symptom-we-know-about-right-now-from-head-to-toe-bd1d47584096).

It also suggests 10-plus potential treatments, many of which are already FDA approved.

https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63

[MultiTroll]

LOL does any other then the 42% cult believe a word of this shit?

HHS Secretary Azar says Nov. 1 coronavirus vaccine deadline has 'nothing to do with elections'

[Winehole23]

LOL does any other then the 42% cult believe a word of this shit?

HHS Secretary Azar says Nov. 1 coronavirus vaccine deadline has 'nothing to do with elections'https://abcnews.go.com/Health/wireStory/cdc-tells-states-ready-distribute-vaccines-nov-72782416

they just announced the rollout. the states are urged to be ready on November 1st.

[DMC]

LOL does any other then the 42% cult believe a word of this shit?

HHS Secretary Azar says Nov. 1 coronavirus vaccine deadline has 'nothing to do with elections'

Shouldn't you be inviting people to your donut cookout?

[MultiTroll]

Shouldn't you be inviting people to your donut cookout?
What does this have to do with the virus rollout show?

Or are you stalking me because you miss me?

[Winehole23]

timing public health measures to coincide with a national election is some next level bullshit, don't y'all think?

[ChumpDumper]

Shouldn't you be inviting people to your donut cookout?:cryStart a new thread.:cry

[johnsmith]

timing public health measures to coincide with a national election is some next level bullshit, don't y'all think?

Especially considering all the safety testing that won’t happen. All this is going to do is cause reasonable people to NOT get vaccinated because they’re not comfortable with it....what a shit show.

[SnakeBoy]

I would rather develop an immunity naturally and I really don’t care to take the vaccine (possibly get sick like some do anyway) and then still have a chance to contract other strains. I feel most vaccines are well intended and beneficial, but the flu just isn’t enough of a threat to me to consider.

what seems to bother me the most is the relentless recommendation to get it by government officials. I’m sorry, but I don’t feel like the government cares that much about our well being. I also don’t understand why decisions like mine are so bothersome and/or offensive to others

I'm not bothered or offended. I believe in liberty for all, just curious as to why you choose what you choose as is your right.

So you think you might get sick from the vaccine and would rather get sick naturally. Is that right?

[tholdren]

I'm not bothered or offended. I believe in liberty for all, just curious as to why you choose what you choose as is your right.

So you think you might get sick from the vaccine and would rather get sick naturally. Is that right?

No one healthy should care

[ElNono]

Especially considering all the safety testing that won’t happen. All this is going to do is cause reasonable people to NOT get vaccinated because they’re not comfortable with it....what a shit show.

You hate to see it, tbh

[SnakeBoy]

No one healthy should care

Influenza kills healthy people every year

[boutons_deux]

Antibody test developed for COVID-19 that is sensitive, specific and scalable

UNIVERSITY OF TEXAS AT AUSTIN

is more accurate and can handle a much larger number of donor samples at lower overall cost

than standard antibody tests currently in use.

In the near term, the test can be used to accurately identify the best donors for convalescent plasma therapy (https://cns.utexas.edu/news/covid-19-convalescent-plasma-therapy-is-safe-with-76-of-patients-improving) and

measure how well candidate vaccines and other therapies elicit an immune response.

https://www.eurekalert.org/pub_releases/2020-09/uota-atd091120.php

[boutons_deux]

Blood plasma looked like a promising covid-19 treatment.

Then Trump got involved.


The president’s politicized rollout of a plasma authorization triggered a backlash,

disrupting a business coalition’s carefully honed message.

https://www.washingtonpost.com/business/2020/09/11/plasma-coronavirus-blood-industry-data


:lol The Trash Touch, everything goes to shit.

[hater]

Especially considering all the safety testing that won’t happen. All this is going to do is cause reasonable people to NOT get vaccinated because they’re not comfortable with it....what a shit show.

Dont forget calling it warp speed :lmao

Note to CDC, next time do not let Ronalga Dump make up nicknames for your products :lmao

[hater]

Russians did good calling it sputnik tbqh. It was fast but it worked.

[hater]

Even then, Russians are much like anyone:

Just under half (45.6 percent) of surveyed Russians don’t want to be vaccinated against coronavirus, regardless of where the vaccine comes from, according to a new study by Moscow’s Higher School of Economics (HSE).

The research revealed that just 13.2 percent of those questioned want to get vaccinated as soon as possible, with a further 4.6 percent wishing to wait a few months. Of those who refuse to be immunized, almost a quarter (24.6 percent) still intend to monitor the results of mass vaccination, with another quarter (25 percent) saying they’re entirely opposed to all vaccines.

Part of the country’s lack of enthusiasm for a vaccine may be explained by the belief that Covid-19 isn’t so serious. 43.4 percent of respondents believe that the danger of the epidemic is exaggerated or invented by “interested parties.” This is a considerable rise from a similar survey taken in May, which discovered that just a third (32.8 percent) of the country were coronavirus skeptics.


Would you say


Hate called it :tu

[hater]

Governments fucked up by claiming the vaccine would be developed in record speed and promising it on day one. They fucked up royally.

Vaccine should have been the last topic. They should have given ways to combat and contain this.

They fucked up. All of them

[Dirks_Finale]

No one healthy should care

What if said healthy person has an immunocompromised spouse at home? And they visit their dad every week who has diabetes/hypertension, etc?

[hater]

What if said healthy person has an immunocompromised spouse at home? And they visit their dad every week who has diabetes/hypertension, etc?

A shot of clorox a day will keep the bug at bay

[Dirks_Finale]

Russians will get vaccinated or Putin will poison that azz :lol


Even then, Russians are much like anyone:

Just under half (45.6 percent) of surveyed Russians don’t want to be vaccinated against coronavirus, regardless of where the vaccine comes from, according to a new study by Moscow’s Higher School of Economics (HSE).

The research revealed that just 13.2 percent of those questioned want to get vaccinated as soon as possible, with a further 4.6 percent wishing to wait a few months. Of those who refuse to be immunized, almost a quarter (24.6 percent) still intend to monitor the results of mass vaccination, with another quarter (25 percent) saying they’re entirely opposed to all vaccines.

Part of the country’s lack of enthusiasm for a vaccine may be explained by the belief that Covid-19 isn’t so serious. 43.4 percent of respondents believe that the danger of the epidemic is exaggerated or invented by “interested parties.” This is a considerable rise from a similar survey taken in May, which discovered that just a third (32.8 percent) of the country were coronavirus skeptics.


Would you say


Hate called it :tu

[Dirks_Finale]

A shot of clorox a day will keep the bug at bay

That and maybe eat light bulbs...a sort of cleansing.

[boutons_deux]

Bad Blood?

Why Transfusions from Women May Be Risky for Men

men who received blood transfusions (https://www.livescience.com/50406-blood-donation-allergies.html) from previously pregnant female donors were 13 percent more likely to die during the study period,

compared with men who received blood transfusions from male donors.

In contrast, men who received blood transfusions from women who had never been pregnant were not at increased risk of death over the study period, compared with men who received transfusions from other men,

https://www.livescience.com/60702-blood-transfusions-women-men.html