Coronavirus is one mutation away from infecting millions

[Spurs Homer]

Kemp is lying.

Pretending to be an idiot is the penultimate CYA for bad decisions. It is usually a prelude to more of the same.

maybe he relied on those WH nuremberg pressers?

[vy65]

1245715120883470337

Snippet:

The world is about to find out. So far, about one in 10 deaths in the United States from COVID-19 has occurred in the four-state arc of Louisiana, Mississippi, Alabama, and Georgia, according to data assembled by the COVID Tracking Project, a volunteer collaboration incubated at The Atlantic. New Orleans is on pace to become the next global epicenter of the pandemic. The virus has a foothold in southwestern Georgia, and threatens to overwhelm hospitals in the Atlanta metropolitan area. The coronavirus is advancing quickly across the American South. And in the American South, significant numbers of younger people are battling health conditions that make coronavirus outbreaks more perilous.

The numbers emerging seem to indicate that more young people in the South are dying from COVID-19. Although the majority of coronavirus-related deaths in Louisiana are still among victims over 70 years old, 43 percent of all reported deaths have been people under 70. In Georgia, people under 70 make up 49 percent of reported deaths. By comparison, people under 70 account for only 20 percent of deaths in Colorado. “Under 70” is a broad category, not really useful for understanding what’s going on. But digging deeper reveals more concerning numbers. In Louisiana, people from the ages of 40 to 59 account for 22 percent of all deaths. The same age range in Georgia accounts for 17 percent of all deaths. By comparison, the same age group accounts for only about 10 percent of all deaths in Colorado, and 6 percent of all deaths in Washington State. These statistics suggest that middle-aged and working-age adults in the two southern states are at much greater risk than their counterparts elsewhere; for some reason, they are more likely to die from COVID-19.

My guess is that people aged 40-59 in Georgia and Louisiana and orders of magnitude less healthy than that cohort is in Colorado and Washington state.

[RandomGuy]

Kemp is lying.

Pretending to be an idiot is the penultimate CYA for bad decisions. It is usually a prelude to more of the same.

Very good point. I keep assuming they are idiots, and forget they can be lying as well.

[RandomGuy]

My guess is that people aged 40-59 in Georgia and Louisiana and orders of magnitude less healthy than that cohort is in Colorado and Washington state.

Map it out to rates of diabetes and other health factors.

I also wonder if having a population at higher elevation has an effect. Your lungs work harder by default. Wyoming swim teams tend to do well at lower elevations. :D

[Winehole23]

maybe he relied on those WH nuremberg pressers?Nope. He's a cynical liar. Like the President, he's content to fiddle while his country burns.

[vy65]

Map it out to rates of diabetes and other health factors.

I also wonder if having a population at higher elevation has an effect. Your lungs work harder by default. Wyoming swim teams tend to do well at lower elevations. :D

Or hikes vs. rascal scooters owned ...

[Trill Clinton]

1245492282100334592

“[The 44-year-old suspect from] San Pedro, was charged with deliberately wrecking a train during the incident Tuesday, which lead to a derailment and fuel leak, according to charges,” The Los Angeles Times reported (https://www.latimes.com/california/story/2020-04-01/man-charged-derailing-train-hospital-ship-mercy). “Prosecutors allege that [the suspect] derailed the train and deliberately crashed through barriers designed to stop engines before grinding to a halt 250 yards from the Mercy.”

According to an affidavit, the suspect allegedly told a California Highway Patrol officer, “You only get this chance once. The whole world is watching. I had to. People don’t know what’s going on here. Now they will.”

[SnakeBoy]

My guess is that people aged 40-59 in Georgia and Louisiana and orders of magnitude less healthy than that cohort is in Colorado and Washington state.

Because of all the blacks?

[pgardn]

Nope. He's a cynical liar. Like the President, he's content to fiddle while his country burns.

This word has been sitting in my hip pocket.

Im being cynical in believing this is how the red team operates, especially WH operates.
Some posters of varying political persuasions on this site exhibit this so brazenly... Living in a sad world of paranoia because of it.

This is what winning a campaign and keeping power through lying breeds, saturated cynical brains.
Its like they take old-Darwinian views to the core, and forget people can actually reject make choices and reject such simplistic widely held views about human nature. Some Christians fob it Off with, “we know we are going to sin, so here goes, I’m a sinner”.

[Winehole23]

Innovative!

https://ftalphaville.ft.com/2020/04/01/1585782924000/Elon-Musk-promised-ventilators--These-are-BPAP-machines-/

[pgardn]

Because of all the blacks?

Poor, lack of education, lack of knowledge about proper hygiene and basic health.
Same in white rural areas. Usually smoke more, eat more junk, etc...

My hypotheses.

[monosylab1k]

https://twitter.com/realDonaldTrump/status/1237027356314869761?s=20

Well this one aged like milk...

Also definitely got regurgitated on here by DarrinS

[hater]

Germany confirmed asymptomatics can spread the virus in January

why did we not prepare?



https://www.nejm.org/doi/pdf/10.1056/NEJMc2001468?articleTools=true

[hater]

https://twitter.com/CharlesMBlow/status/1245680178455609344?s=20

[SnakeBoy]

Poor, lack of education, lack of knowledge about proper hygiene and basic health.
Same in white rural areas. Usually smoke more, eat more junk, etc...

My hypotheses.

Could it be that the author and you are just using percentage differences in comparing 2 small data sets in order to fit the virus into his preconceived views of the south.

[SnakeBoy]

Germany confirmed asymptomatics can spread the virus in January

why did we not prepare?



https://www.nejm.org/doi/pdf/10.1056/NEJMc2001468?articleTools=true

How would you have prepared the country Hater?

[hater]

How would you have prepared the country Hater?

immediately order billions of PPE and hudreds of thousands of ventilators to start?

organize a competent task force immediately? (without Mike Penis)

seems like CDC had to be waken up from a slumber and now our medics are wearing rain ponchos and trash bags as PPE

i mbarrasing

[hater]

oh and when was Trumps last Rally? curious about that

[LaMarcus Bryant]

1245715120883470337

Snippet:

The world is about to find out. So far, about one in 10 deaths in the United States from COVID-19 has occurred in the four-state arc of Louisiana, Mississippi, Alabama, and Georgia, according to data assembled by the COVID Tracking Project, a volunteer collaboration incubated at The Atlantic. New Orleans is on pace to become the next global epicenter of the pandemic. The virus has a foothold in southwestern Georgia, and threatens to overwhelm hospitals in the Atlanta metropolitan area. The coronavirus is advancing quickly across the American South. And in the American South, significant numbers of younger people are battling health conditions that make coronavirus outbreaks more perilous.

The numbers emerging seem to indicate that more young people in the South are dying from COVID-19. Although the majority of coronavirus-related deaths in Louisiana are still among victims over 70 years old, 43 percent of all reported deaths have been people under 70. In Georgia, people under 70 make up 49 percent of reported deaths. By comparison, people under 70 account for only 20 percent of deaths in Colorado. “Under 70” is a broad category, not really useful for understanding what’s going on. But digging deeper reveals more concerning numbers. In Louisiana, people from the ages of 40 to 59 account for 22 percent of all deaths. The same age range in Georgia accounts for 17 percent of all deaths. By comparison, the same age group accounts for only about 10 percent of all deaths in Colorado, and 6 percent of all deaths in Washington State. These statistics suggest that middle-aged and working-age adults in the two southern states are at much greater risk than their counterparts elsewhere; for some reason, they are more likely to die from COVID-19.

The final crescendo of the oll southern strategy

[hater]

good ol southern cooking?

[Winehole23]

Germany confirmed asymptomatics can spread the virus in January

why did we not prepare?



https://www.nejm.org/doi/pdf/10.1056/NEJMc2001468?articleTools=trueThat would have required empathy and professionalism, which are, uh, not in Trump's bailiwick. It would also have required him to put the American people before his own ambition and personal glory.

This always has been -- and still is -- primarily a problem of PR and optics for Trump. Dealing with it qua public health threat was never going to start until it was too late.

Trump's preoccupation with the possible effect of COVID-19 on his own political fortunes (and his aversion to the that perceived negative effect) will have cost 10s of thousands of US lives before this is done.

[DarrinS]

Well this one aged like milk...

Also definitely got regurgitated on here by DarrinS


I don't know why you keep trying to dunk on me. I already admitted I was wrong weeks ago.

[weebo]

1245513642319151110

how do idiots like this get electedhttps://www.thecoli.com/styles/default/xenforo/smilies/mindblown.png

....because bigger idiots elect them

[MannyIsGod]

Things the US could have doe sooner and resulted in saved lives: Shelter in place much sooner, order production of vents sooner, order production of PPE sooner, followed the Pandemic playbook, not reduced staffing at pandemic related facilities such as the CDC, and the list goes on.

We could have avoided this. Anyone who thinks it was unavoidable is being intellectually dishonest.

[boutons_deux]

Will the coronavirus wilt in summer heat? Maybe, but don’t count on it

https://www.politifact.com/article/2020/mar/30/will-coronavirus-wilt-summer-heat-maybe-dont-count/

[Blake]

https://twitter.com/realDonaldTrump/status/1237027356314869761?s=20

Well this one aged like milk...

Also definitely got regurgitated on here by DarrinS

And he'll get reelected

[DarrinS]

https://www.youtube.com/watch?feature=youtu.be&v=k4VPnjIXAb8

[Winehole23]

DarrinS teasing cable news for a turned corner

[Spurs Homer]

The EVIDENCE was overwhelming to convict trump in the impeachment.

Republicans were warned and were begged -to do their duty and convict and save the country (planet) from trumps future fuckery-

it was a golden opportunity to do their duty while saving american lives.

They were repeatedly warned that an emboldened trump would be dangerous.

Schiff during the trial, “you KNOW you cannot trust him- you KNOW he will not stop- you KNOW he is guilty - you KNOw he will do it again “


The evidence would have protected these Republicans from angry trump cultists-


it was a fucking layup.


They chose to cover up his crimes, they chose to be complicit in trumps criminality and his incompetence-

trump now has blood on his hands - no different than the blood of puerto ricans-

the GOP and 33% of american trump cultists have blood on their hands.

[Winehole23]

Laurie Garrett takes down Trump and Xi

https://newrepublic.com/amp/article/157118/trump-xi-jinping-america-china-blame-coronavirus-pandemic

https://www.amazon.com/Coming-Plague-Emerging-Diseases-Balance/dp/0140250913

[monosylab1k]

DarrinS teasing cable news for a turned corner

“:cry I already said I was wrong for believing the bullshit coming from Trump and Fox News! Now here’s some information from Trump and Fox News that I will pass on to everyone!”

[Blake]

Laredo making everyone wear masks in public along with a 10pm curfew

[DMC]

How often should they be maintained?
If they are periodically rotated through maintenance cycles, how many cycles happened in those 7 months, and what is both the absolute number, and the proportion of those ventilators that didn't get serviced?

(edit)

And yes, complex machines have fail rates out of storage. The critical thinking question here is what is that rate, and how did the failure to maintain them affect that. It seems to me that we need more information to effectively evaluate this fact.

Well do the research on that before you spout off about thousands failing.

Also the oxygen hoses didn't just get up and leave when the contract ended. It's quite likely and even probable that a good portion of those stored units were never even touched just pencil whipped on a sign off sheet.

[DMC]

Laurie Garrett takes down Trump and Xi

https://newrepublic.com/amp/article/157118/trump-xi-jinping-america-china-blame-coronavirus-pandemic

https://www.amazon.com/Coming-Plague-Emerging-Diseases-Balance/dp/0140250913

I'm sure they are reeling from her opinion.

[DarrinS]

“:cry I already said I was wrong for believing the bullshit coming from Trump and Fox News! Now here’s some information from Trump and Fox News that I will pass on to everyone!”

The video I posted has nothing to do with trump.

[vy65]

Laurie Garrett takes down Trump and Xi

https://newrepublic.com/amp/article/157118/trump-xi-jinping-america-china-blame-coronavirus-pandemic

https://www.amazon.com/Coming-Plague-Emerging-Diseases-Balance/dp/0140250913

It's shocking to me how simple and straightforward DJT's fuck up is: he demonstrably lied to the American people. His repeated assertions of having "it" under control were, and are, flat out lies. The president lied to the public and people are dying as a result. I don't understand why this isn't a bigger deal.

[clambake]

It's shocking to me how simple and straightforward DJT's fuck up is: he demonstrably lied to the American people. His repeated assertions of having "it" under control were, and are, flat out lies. The president lied to the public and people are dying as a result. I don't understand why this isn't a bigger deal.

cult is why.


we need to waco this cult, too.

[vy65]

cult is why.


we need to waco this cult, too.

I think I diverge from some of the other liberal posters here because I entertain the possibility of disenfranchising people. In theory, if you don't believe in the basic fundamentals of science, if you can't agree on what is true and what is not, and think you're entitled to your own set of facts, then you should have no business determining this country's leaders. And that is because, as we're seeing, people will die.

[boutons_deux]

It's shocking to me how simple and straightforward DJT's fuck up is: he demonstrably lied to the American people. His repeated assertions of having "it" under control were, and are, flat out lies. The president lied to the public and people are dying as a result. I don't understand why this isn't a bigger deal.

Impeach

[DMC]

cult is why.


we need to waco this cult, too.

You first. Lead by example.

[vy65]

Impeach

Yeah that worked

[clambake]

You first. Lead by example.

hello manatee!

[monosylab1k]

The video I posted has nothing to do with trump.

If it’s from Fox, it has everything to do with Trump.

[Will Hunting]

I think I diverge from some of the other liberal posters here because I entertain the possibility of disenfranchising people. In theory, if you don't believe in the basic fundamentals of science, if you can't agree on what is true and what is not, and think you're entitled to your own set of facts, then you should have no business determining this country's leaders. And that is because, as we're seeing, people will die.
I agree with this particularly with the 25% of this country that thinks “the end times are near”.

If you think we’re quickly approaching the rapture then you shouldn’t have a say in what the future of America/mankind is going to look like.

[boutons_deux]

Georgia's Idiot Governor Says He Didn't Know People Could Spread Covid-19 Without Symptoms (https://gizmodo.com/georgias-idiot-governor-says-he-didnt-know-people-could-1842636191)

https://www.spurstalk.com/forums/image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAE AAAICTAEAOw==
https://www.spurstalk.com/forums/image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAE AAAICTAEAOw==
https://www.spurstalk.com/forums/image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAE AAAICTAEAOw==
https://gizmodo.com/georgias-idiot-governor-says-he-didnt-know-people-could-1842636191?utm_source=gizmodo_newsletter&utm_medium=email&utm_campaign=2020-04-02

Fuck 'em all

[spurraider21]

its anecdotal evidence with statistical analysis performed by the dr's son :lol

[DMC]

hello manatee!

That's what I thought

[Splits]

https://www.youtube.com/watch?feature=youtu.be&v=k4VPnjIXAb8

What I don't get about all these doctor's claims is how they've been treating "all their patients" with hydroxychloroquine when the FDA just approved prescription outside clinical trials a few days ago. He's been a part of these trials or breaking the law? If he's part of the trials, he's asking his sons instead to do the analysis?

[DMC]

I was under the impression that hydroxychloroquine was a prescription medication available already for malaria.

[boutons_deux]

In Desperation, New York State Pays Up to 15 Times the Normal Prices for Medical Equipment
https://www.propublica.org/article/in-desperation-new-york-state-pays-up-to-15-times-the-normal-price-for-medical-equipment?utm_source=pardot&utm_medium=email&utm_campaign=majorinvestigations (https://www.propublica.org/article/in-desperation-new-york-state-pays-up-to-15-times-the-normal-price-for-medical-equipment?utm_source=pardot&utm_medium=email&utm_campaign=majorinvestigations)

[Splits]

I was under the impression that hydroxychloroquine was a prescription medication available already for malaria.

You can't prescribe a drug approved for one indication (malaria) for another (covid) unless you are part of a clinical trial (which is usually double-blinded meaning some get placebos and neither doc or patient know if they got the actual drug) or if the FDA issues an emergency order, which they did Sunday.

[ChumpDumper]

Still wondering why people feel compelled to defend Trump. He failed the nation and people are dying because of his feckless inaction and lies.

What's in it for his defenders?

[Splits]

FDA statement:

https://www.hhs.gov/about/news/2020/03/29/hhs-accepts-donations-of-medicine-to-strategic-national-stockpile-as-possible-treatments-for-covid-19-patients.html (https://www.hhs.gov/about/news/2020/03/29/hhs-accepts-donations-of-medicine-to-strategic-national-stockpile-as-possible-treatments-for-covid-19-patients.html)

[Xevious]

What I don't get about all these doctor's claims is how they've been treating "all their patients" with hydroxychloroquine when the FDA just approved prescription outside clinical trials a few days ago. He's been a part of these trials or breaking the law? If he's part of the trials, he's asking his sons instead to do the analysis?
Docs have been treating patients with it for weeks now. From what I can tell, it's more of a "why not" situation.

[Splits]

Docs have been treating patients with it for weeks now. From what I can tell, it's more of a "why not" situation.

lol no

that's not how this works. my job is literally knowing how this works.

[DMC]

You can't prescribe a drug approved for one indication (malaria) for another (covid) unless you are part of a clinical trial (which is usually double-blinded meaning some get placebos and neither doc or patient know if they got the actual drug) or if the FDA issues an emergency order, which they did Sunday.

Apparently doctors in Michigan were doing just that and were warned by the governor I guess to cut that shit out. Now they have requested more of that drug but those two are not mutually exclusive. It's interesting how some of these news agencies latch onto these things as if they are contradictory stances. Perfectly understandable that authorities would have an issue with doctors prescribing untested medications to their family and friends for panic storing.

[Xevious]

lol no

that's not how this works. my job is literally knowing how this works.
How what works?

[boutons_deux]

Donald Trump misses key facts in claim that New York governor refused to buy ventilators in 2015




A 2015 New York state report said that in the case of a “severe” pandemic, the state would be short about 16,000 ventilators during the peak week. But the report did not recommend buying 16,000 ventilators, and did not indicate whether the state was at a fiscal position to purchase them.
The state did not plan to increase its ventilator stockpile because it anticipated that in the event of a severe crisis, there would be shortage of trained staff to operate them and demand would outweigh any emergency stockpile.
The report said the state had to balance the likely ventilator shortage with the need for adequate funding for current and ongoing health care expenses.





politifact.com/factchecks/2020/mar/25/donald-trump/donald-trump-misses-key-facts-claim-new-york-gover/

[ChumpDumper]

lol no

that's not how this works. my job is literally knowing how this works.How does this work? So far all I've heard about this is

1) anecdotes from French doctor.

2) anecdotes from NY doctor.

3) anecdotes from NJ doctor with sons who did....something....

4) anecdotes from Dr. Oz about China.

As widely available as the drugs seem to be, shouldn't there be more than this out there?

[Xevious]

I was under the impression that hydroxychloroquine was a prescription medication available already for malaria.
As well as autoimmune disorders, yes.

[Splits]

How what works?

The rules around what a doctor can and cannot do. There's no discretion when it comes to prescribing medication. It is either legal or illegal.

[hater]

lol overstatement

they just quarantined a city of 11 million

https://twitter.com/petergleick/status/1220062726891790342?s=21

the virus is mutating

its the mainstream media who are downplaying this

:lmao thinking a paper mask and thermometer can stop this

some clown “doctor” on CNBC just said this is a nothingburger and laughed off the measly 500 infections and 17 dead. its only been 3 days ya dumbfuck and do you really think only 500 infections?

CALLED IT

WE HIT 1 MILLION

[boutons_deux]

The Social-Distancing Culture War Has Begun

Across the country, social distancing is morphing from a public-health to political act. The consequences could be disastrous.

At the driving range, while Frost and his like-minded friends slathered on hand sanitizer and kept six feet apart, the

white-haired Republicans seemed to delight in breaking the new rules.

They made a show of shaking hands, and complained loudly about the “stupid hoax” being propagated by virus alarmists.

When their tee times were up, they piled defiantly into golf carts, shoulder to shoulder, and sped off toward the first hole.

social distancing has come to be viewed in some quarters as a political act—a way to signal which side you’re on.

“I would rather die than kill the country,” Glenn Beck

Dennis Prager:

“That attitude, that the only value is saving a life … it leads to cowardice. :lol

It has to. No one can die? Then it’s not a war" :lol rightwingnutjob "logic" wannabe Macho Man

proudly told me how unfazed he and his conservative neighbors were by the threat of an outbreak.

as a conservative, he’s become convinced that many Democrats are so invested in the idea that the virus will be disastrous that they’re pushing for prolonged, unnecessary shutdowns in pursuit of vindication.

Katherine Vincent-Crowson, a 35-year-old self-defense instructor :lol from Slidell, Louisiana, :lol

A devotee of Ayn Rand, :lol that explains the stupidity

Vincent-Crowson told me Louisiana’s shelter-in-place order was a frightening example of government overreach.

“I’m a libertarian … :lol that explains the stupidity

I don’t really like being told what to do.”

https://www.theatlantic.com/politics/archive/2020/03/social-distancing-culture/609019/

[DMC]

The rules around what a doctor can and cannot do. There's no discretion when it comes to prescribing medication. It is either legal or illegal.
Don't doctors prescribe off-label medications all the time without need for approval from the FDA? Doesn't the FDA only regulate the manufacturer of the drug so that they cannot advertise its benefits without these tests and FDA approval?

[hater]

Don't doctors prescribe off-label medications all the time without need for approval from the FDA? Doesn't the FDA only regulate the manufacturer of the drug so that they cannot advertise its benefits without these tests and FDA approval?

:lol no

teacher give him an F :lol

[Xevious]

The rules around what a doctor can and cannot do. There's no discretion when it comes to prescribing medication. It is either legal or illegal.
Very well. But the fact remains that we've been prescribing the plaquenil/azithromycin combo for at least two weeks now to COVID patients, inpatient and out. But I've not read any concrete evidence that it reduces or shortens symptoms.

[Splits]

How does this work? So far all I've heard about this is

1) anecdotes from French doctor.

2) anecdotes from NY doctor.

3) anecdotes from NJ doctor with sons who did....something....

4) anecdotes from Dr. Oz about China.

As widely available as the drugs seem to be, shouldn't there be more than this out there?

I'm strictly speaking about the legality and regulatory approval of using a prescription drug to treat an indication for which it is not approved.

It's very simple, actually.

1) Drug is FDA approved for an indication (malaria)
2) Drug can only be prescribed by doctor to patient diagnosed with such disease
3) If a doctor breaks this law, his license is gone, criminally charged potentially, etc
4) Drugs approved for one indication (malaria) can be approved for clinical trials on a population of another indication (covid)
5) Clinical trials can be initiated immediately upon approval, this has been ongoing for weeks. But it is controlled, these are double-blind, there are placebos, etc
6) The law described in (2) can be lifted by FDA emergency order, which they issued on Sunday. This:


The U.S. Food and Drug Administration (FDA (https://www.fda.gov/)) issued an Emergency Use Authorization (EUA (https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization)) to BARDA to allow hydroxychloroquine sulfate and chloroquine phosphate products donated to the Strategic National Stockpile (SNS) to be distributed and prescribed by doctors to hospitalized teen and adult patients with COVID-19, as appropriate, when a clinical trial is not available or feasible.

[SnakeBoy]

What I don't get about all these doctor's claims is how they've been treating "all their patients" with hydroxychloroquine when the FDA just approved prescription outside clinical trials a few days ago. He's been a part of these trials or breaking the law? If he's part of the trials, he's asking his sons instead to do the analysis?

About 30% of all prescriptions are for off label use. It's always been the case that Docs can prescribe FDA approved meds for other than FDA approved use.

Why is there such a hope that these drugs don't work from you lefties? Is it just cuz Trump?

[DMC]

:lol no

teacher give him an F :lol
From the FDA perspective, once the FDA approves a drug, healthcare providers generally may prescribe the drug for an unapproved use when they judge that it is medically appropriate for their patient.

From the FDA website

[DMC]

There are MDs who post here. Hopefully one of them will chime in. However the FDA website is quite clear.

[RandomGuy]

Still wondering why people feel compelled to defend Trump. He failed the nation and people are dying because of his feckless inaction and lies.

What's in it for his defenders?

The feeling that they aren't suckers. No one wants to think they were gullible enough to fall for a con man. Many don't bother to report to the police for that reason.

[boutons_deux]

what is dosage mg / Kg of body weight?

enough of it will fuck up your eyes

[vy65]

You can't prescribe a drug approved for one indication (malaria) for another (covid) unless you are part of a clinical trial (which is usually double-blinded meaning some get placebos and neither doc or patient know if they got the actual drug) or if the FDA issues an emergency order, which they did Sunday.

Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.[1] Both prescription drugs and over-the-counter drugs (OTCs) can be used in off-label ways, although most studies of off-label use focus on prescription drugs.

Off-label use is generally legal unless it violates ethical guidelines or safety regulations. The ability to prescribe drugs for uses beyond the officially approved indications is commonly used to good effect by healthcare providers. For example, methotrexate is commonly used off-label because its immunomodulatory effects relieve various disorders.[2] However, off-label use can entail health risks and differences in legal liability. Marketing of pharmaceuticals for off-label use is usually prohibited.

[DMC]

Why might an approved drug be used for an unapproved use?

From the FDA perspective, once the FDA approves a drug, healthcare providers generally may prescribe the drug for an unapproved use when they judge that it is medically appropriate for their patient.
You may be asking yourself why your healthcare provider would want to prescribe a drug to treat a disease or medical condition that the drug is not approved for. One reason is that there might not be an approved drug to treat your disease or medical condition. Another is that you may have tried all approved treatments without seeing any benefits. In situations like these, you and your healthcare provider may talk about using an approved drug for an unapproved use to treat your disease or medical condition.


:lol hater

[vy65]

Doesn't sound like Splits is all that great at his job.

[ChumpDumper]

About 30% of all prescriptions are for off label use. It's always been the case that Docs can prescribe FDA approved meds for other than FDA approved use.

Why is there such a hope that these drugs don't work from you lefties? Is it just cuz Trump?Why do you have to make a straw man to defend Trump?

So far all I've heard about this is

1) anecdotes from French doctor.

2) anecdotes from NY doctor.

3) anecdotes from NJ doctor with sons who did....something....

4) anecdotes from Dr. Oz about China.

As widely available as the drugs seem to be, shouldn't there be more than this out there?

[MannyIsGod]

I can't speak for anyone else but I hope the drug is actually working like we hear from these anecdotes. If there's no downside, let people try. We're in a literal emergency.

[DMC]

Doesn't sound like Splits is all that great at his job.

You should see his W-2 form though

[Splits]

Don't doctors prescribe off-label medications all the time without need for approval from the FDA? Doesn't the FDA only regulate the manufacturer of the drug so that they cannot advertise its benefits without these tests and FDA approval?

It's actually a good point. Off-label prescribing is perfectly legal, but it comes with the risk of getting it wrong. So if a doc "knows" he can prescribe you some Vicodin for your headache and you aren't going to die, fine. But the claims by these doctors are they are giving these to semi-symptomatic patients not bringing patients off respirators, with no clinical evidence it doesn't make it worse, is a huge risk. If it turns out killing semi-symptomatic patients, they would be liable without FDA cover, which they got Sunday.

[Splits]

I can't speak for anyone else but I hope the drug is actually working like we hear from these anecdotes. If there's no downside, let people try. We're in a literal emergency.

And there's 30m+ doses available right now with another 100m coming within a month

[vy65]

I can't speak for anyone else but I hope the drug is actually working like we hear from these anecdotes. If there's no downside, let people try. We're in a literal emergency.


For one, hydroxychloroquine may have been safely prescribed for decades, but it is not benign — the drug can cause irregular heart rhythms. Given the mortality risk, the American College of Cardiology suggests any patient prescribed the drug should be part of a clinical trial, while conceding the benefit may outweigh the risk in Covid-19 patients who are in intensive care units or over 70 years old.

Another problem: The rush to prescribe is making it hard for people with lupus and rheumatoid arthritis to get refills, since the drug was approved to treat those illnesses, as well. Presumably, manufacturer donations to the Strategic National Stockpile will alleviate this concern, but there’s no guarantee if many prescriptions are written for people with mild to moderate symptoms.

This possibility may only have been heightened by the emergency use granted by the FDA, which makes the medication available to hospital patients if a clinical trial is not underway. But this could give the wrong impression about the spotty trial data, which the FDA acknowledged was anecdotal. And as Fernandez Lynch points out, it could be easy for some people to confuse the move with an actual FDA approval.

For now, I think the approach taken by such physicians as David Hill makes the most sense.

https://www.statnews.com/2020/03/31/we-shouldnt-rush-to-use-an-unproven-drug-to-treat-the-coronavirus/

I tried looking for downside, and this was the best I could find ... I don't understand why the drug isn't getting more use.

[ElNono]

You can't prescribe a drug approved for one indication (malaria) for another (covid) unless you are part of a clinical trial (which is usually double-blinded meaning some get placebos and neither doc or patient know if they got the actual drug) or if the FDA issues an emergency order, which they did Sunday.

The FDA issued and exception for NY, but doctors had to have patients sign off that they were part of a clinical trial in order to get the drug (no placebos).

This was a couple of weeks before the general exception.

[ElNono]

About 30% of all prescriptions are for off label use. It's always been the case that Docs can prescribe FDA approved meds for other than FDA approved use.

Why is there such a hope that these drugs don't work from you lefties? Is it just cuz Trump?

I'm hopeful that they do work, my issue is that there's toxicity within them, so if they do NOT work, we might be piling on health problems. That's why we have clinical trials in the first place.

[boutons_deux]

I tried looking for downside, and this was the best I could find ... I don't understand why the drug isn't getting more use.

HCQ has a long list of side effects, including macular degeneration

can't take too much, can't take too long

[hater]

I'm hopeful that they do work, my issue is that there's toxicity within them, so if they do NOT work, we might be piling on health problems. That's why we have clinical trials in the first place.

ma niga

[ElNono]

https://www.statnews.com/2020/03/31/we-shouldnt-rush-to-use-an-unproven-drug-to-treat-the-coronavirus/

I tried looking for downside, and this was the best I could find ... I don't understand why the drug isn't getting more use.

Well, what further complicates things is liability. A doctor in the ICU might not have the entire clinical history of a patient in front of him, and if this patient happens to have a history of cardiac problems that get exacerbated by the drug and the patient dies, without the FDA exception there's a huge liability for the doctor and hospital.

[Splits]

The FDA issued and exception for NY, but doctors had to have patients sign off that they were part of a clinical trial in order to get the drug (no placebos).

This was a couple of weeks before the general exception.

Interesting, I missed that. Would love a link if you've got it handy.

[Splits]

Well, what further complicates things is liability. A doctor in the ICU might not have the entire clinical history of a patient in front of him, and if this patient happens to have a history of cardiac problems that get exacerbated by the drug and the patient dies, without the FDA exception there's a huge liability for the doctor and hospital.

Exactly.

[vy65]

Well, what further complicates things is liability. A doctor in the ICU might not have the entire clinical history of a patient in front of him, and if this patient happens to have a history of cardiac problems that get exacerbated by the drug and the patient dies, without the FDA exception there's a huge liability for the doctor and hospital.

Ironically, this is only an issue if HCQ turns out to be (half) as good as claimed.

[spurraider21]

Doesn't sound like Splits is all that great at his job.


You should see his W-2 form though
:lol

[apalisoc_9]

France is reporting 1300 deaths. Not sure if that's a combined number from yesterday and today.

https://www.worldometers.info/coronavirus/

[Splits]

:lol

I might post the Swiss equivalent. It has only gotten bigger.

[DarrinS]

I can't speak for anyone else but I hope the drug is actually working like we hear from these anecdotes. If there's no downside, let people try. We're in a literal emergency.


I can't get any data on this, but are people with Lupus contracting covid-19? If not, wouldn't that suggest that the drug has a prophylactic effect?

[spurraider21]

i dont know of anybody that is hoping the drug doesnt work as treatment... the issue many take with it is that some are marketing as though we have a sure-thing cure, which can lead to people thinking there's no longer a serious threat, since even if you get infected, you can be cured no questions.

its dangerous to tout it that way, and its dangerous for hospitals to treat this as a one-off cure and send patients home without having the appropriate studies done to confirm that it is, indeed, effective

there are other complications as ElNono pointed out, where there are inherent dangers of using the drug as treatment in the ICU where full records/history aren't available to the doctor who is making the decision

[spurraider21]

France is reporting 1300 deaths. Not sure if that's a combined number from yesterday and today.

https://www.worldometers.info/coronavirus/
that seems oddly high... they had about 500 deaths for the past couple of days per worldometer. i imagine and hope that's just a tabulation error at this point

[DarrinS]

I'd take that HCQ in a heartbeat, if I thought it would keep me off a respirator. Aren't your survival odds only like 20%, if you get on respirator?

[spurraider21]

I'd take that HCQ in a heartbeat, if I thought it would keep me off a respirator. Aren't your survival odds only like 20%, if you get on respirator?
is it necessarily an either/or thing?

if your situation is so grim where you cant breathe without a ventilator, i dont know (literally, i have no medical expertise) that a drug will fix it at that point

[DMC]

I might post the Swiss equivalent. It has only gotten bigger.

Bend over, I'll... well you know.

[SnakeBoy]

I'm hopeful that they do work, my issue is that there's toxicity within them, so if they do NOT work, we might be piling on health problems. That's why we have clinical trials in the first place.

Both chloroquine phosphate and hydroxychloroquine have extremely good safety profiles when taken as directed. The more serious complications come from long term use or people with serious heart conditions. You can look up the safety data of virtually any medication (even over the counter) and find serious side effects that happen to some small percentage of people. Medicine is not an exact science.

Too much is being made out of that couple that took 16 times the recommended dose and fucked themselves up.

Too much is also being made of the word anecdotal. Dr. Fauci's initial use of that word was in response to a specific question about using the drug as a prophylactic (to prevent infection not treatment). Now people like Chump are running with it cuz Trump.

As a treatment, we have good in vitro evidence on their inhibition of viral attachment & replication and chemically why it does. We have decades of studies on their inhibition of cytokine production, that's why they are used for autoimmune diseases. And we have a number of small imperfect studies of actual clinical use. That's all a bit more than anecdotal I would say.

That's all very hopeful. We'll see what the large scale study shows. It's not going to be a wonder drug though where you give it to people near or already in organ failure and they all magically get better. Those medicines do not exist.

[DMC]

I can't get any data on this, but are people with Lupus contracting covid-19? If not, wouldn't that suggest that the drug has a prophylactic effect?

You mean they have to wear condoms?

[LaMarcus Bryant]

I think at this point what annoys me is the people following the company line, trying best to quarantine, but basically reflect the poor timing of the administration. The ones who are doing what they're told but also qualifying it with "we're doing what we can, no way we could have been prepared for this" etc
Despite more and more evidence showing 100% we could have acted in late Jan or early February to prevent the severity.
It's annoying af.

https://www.thedailybeast.com/army-warned-in-early-february-that-coronavirus-could-kill-150000-americans

I mean literally every intel and gov/military group was telling the administration this was going to be the real deal and they sat on their asses for an entire MONTH telling joe bob racist alabama fuck and grandma tv watcher that it was fake.

[DMC]

I'd take that HCQ in a heartbeat, if I thought it would keep me off a respirator. Aren't your survival odds only like 20%, if you get on respirator?

Probably less if you don't.

[DarrinS]

is it necessarily an either/or thing?

if your situation is so grim where you cant breathe without a ventilator, i dont know (literally, i have no medical expertise) that a drug will fix it at that point


Yeah, probably doesn't work if you're already crashing.

[DarrinS]

If you need a laugh

1245407976598286337

[SnakeBoy]

I can't get any data on this, but are people with Lupus contracting covid-19? If not, wouldn't that suggest that the drug has a prophylactic effect?

Medicare is currently working with FDA and doing a search of their database to get that type of data. Just happened yesterday at the urging of Dr Oz (of all people :lol).

[boutons_deux]

The grim death-toll projections the White House offered Monday have already been revised upward

https://www.washingtonpost.com/politics/2020/04/02/grim-death-toll-projections-white-house-offered-monday-have-already-been-revised-upward/?utm_campaign=wp_to_your_health&utm_content=2020_04_02&utm_medium=email&utm_source=newsletter&wpisrc=nl_tyh&wpmk=1

[Nathan89]

More than 1,000 in US die in a single day from coronavirus, doubling the worst daily death toll of the flu

https://www.usatoday.com/story/news/nation/2020/04/01/coronavirus-kills-1-000-single-day-u-s-double-flu/5100905002/

Already knew that more than 1k died but I wanted to post because of the second part of the title. And that's early days with shutting down everything.

[clambake]

I think at this point what annoys me is the people following the company line, trying best to quarantine, but basically reflect the poor timing of the administration. The ones who are doing what they're told but also qualifying it with "we're doing what we can, no way we could have been prepared for this" etc
Despite more and more evidence showing 100% we could have acted in late Jan or early February to prevent the severity.
It's annoying af.

https://www.thedailybeast.com/army-warned-in-early-february-that-coronavirus-could-kill-150000-americans

I mean literally every intel and gov/military group was telling the administration this was going to be the real deal and they sat on their asses for an entire MONTH telling joe bob racist alabama fuck and grandma tv watcher that it was fake.
your post is surrounded by one of those fucks right now.

[SnakeBoy]

is it necessarily an either/or thing?

if your situation is so grim where you cant breathe without a ventilator, i dont know (literally, i have no medical expertise) that a drug will fix it at that point


Yeah, probably doesn't work if you're already crashing.

There's no reason to believe chloroquine/hydroxychloroquine are going to work in those cases. Probably this will need to be started early in the infection.

They are doing trials of many more drugs. Some of them much more powerful rheumatoid arthritis drugs that offer more hope for critically ill. The idea is to just shut down their immune response. These (like chloroquine/hydroxychloroquine) are immunosuppressive drugs.

[Nathan89]

I think at this point what annoys me is the people following the company line, trying best to quarantine, but basically reflect the poor timing of the administration. The ones who are doing what they're told but also qualifying it with "we're doing what we can, no way we could have been prepared for this" etc
Despite more and more evidence showing 100% we could have acted in late Jan or early February to prevent the severity.
It's annoying af.

https://www.thedailybeast.com/army-warned-in-early-february-that-coronavirus-could-kill-150000-americans

I mean literally every intel and gov/military group was telling the administration this was going to be the real deal and they sat on their asses for an entire MONTH telling joe bob racist alabama fuck and grandma tv watcher that it was fake.

Dude basically all media outlets were posting that this is nothing compared to the regular flu in late January and early February. If the Washington Post (not that I think highly of them) is pushing that then there is zero chance of the average American will do something. You have a point but late January and early February is not a reasonable timeline given what was actually being pushed during that time period.

Edit:. I suppose you were talking about lower levels of government. Your expectations of them are also too high.

[Nathan89]

If you need a laugh

1245407976598286337

I've been binging Taskmaster (uk show, first four seasons available on YouTube) lately and I've got tons of laughs from that tbh. Highly recommended.

[TSA]

https://twitter.com/peterjhasson/status/1243213491252670466

https://twitter.com/peterjhasson/status/1245755143481671683

[LaMarcus Bryant]

Dude basically all media outlets were posting that this is nothing compared to the regular flu in late January and early February. If the Washington Post (not that I think highly of them) is pushing that then there is zero chance of the average American will do something. You have a point but late January and early February is not a reasonable timeline given what was actually being pushed during that time period.

Edit:. I suppose you were talking about lower levels of government. Your expectations of them are also too high.

WGAF about news outlets? The media coverage to common people like us is meaningless. Our leadership was told by people who are paid to know these things that this was coming and they did nothing. And we're getting document after document of warnings our leaders recieved and did nothing about. January, February. The government's ability to get a response going would have shaped that part of it, not vice versa

[ChumpDumper]

Both chloroquine phosphate and hydroxychloroquine have extremely good safety profiles when taken as directed. The more serious complications come from long term use or people with serious heart conditions. You can look up the safety data of virtually any medication (even over the counter) and find serious side effects that happen to some small percentage of people. Medicine is not an exact science.

Too much is being made out of that couple that took 16 times the recommended dose and fucked themselves up.

Too much is also being made of the word anecdotal. Dr. Fauci's initial use of that word was in response to a specific question about using the drug as a prophylactic (to prevent infection not treatment). Now people like Chump are running with it cuz Trump.

As a treatment, we have good in vitro evidence on their inhibition of viral attachment & replication and chemically why it does. We have decades of studies on their inhibition of cytokine production, that's why they are used for autoimmune diseases. And we have a number of small imperfect studies of actual clinical use. That's all a bit more than anecdotal I would say.

That's all very hopeful. We'll see what the large scale study shows. It's not going to be a wonder drug though where you give it to people near or already in organ failure and they all magically get better. Those medicines do not exist.GFY dude.

I've said several times I HOPE IT WORKS. Quit making straw men to defend Trump. I asked you if there was anything else beyond what I listed.

Looks like there's nothing.

[Spurminator]

Nathan continues to be driven by the preposterous delusion that The Media is the elected leader of the United States, ignoring and excusing the failures of Government leaders (well, Republican ones at least) because MSNBC ran something sensationalist and inaccurate.

[midnightpulp]

^The WHO is a disgusting organization.

[boutons_deux]

France is reporting 1300 deaths. Not sure if that's a combined number from yesterday and today.

https://www.worldometers.info/coronavirus/

4032 total

https://www.statnews.com/2020/03/26/covid-19-tracker/

[spurraider21]

Too much is also being made of the word anecdotal. Dr. Fauci's initial use of that word was in response to a specific question about using the drug as a prophylactic (to prevent infection not treatment). Now people like Chump are running with it cuz Trump.
no. anybody who has even moderate scientific literacy knows the importance of the word "anecdotal" in these areas

[ChumpDumper]

no. anybody who has even moderate scientific literacy knows the importance of the word "anecdotal" in these areasIt describes literally every pimping of this drug. I would actually expect more than four anecdotes at this point given how widespread both the virus and the media coverage of the game changing miracle drug are.

[Medvedenko]

Ugh oh, Little Jared is on the scene on the old presser.....

[ChumpDumper]

https://twitter.com/peterjhasson/status/1243213491252670466

https://twitter.com/peterjhasson/status/1245755143481671683Yeah, China bad.

Everyone but Trump knew that.

Why did Trump trust China?

[boutons_deux]

NY death rate daily seems to be stabilizing, ands a lower %age of national deaths

[TimDunkem]

^But cases overall in NY are rising

[MannyIsGod]

I can't get any data on this, but are people with Lupus contracting covid-19? If not, wouldn't that suggest that the drug has a prophylactic effect?

We can't get data on if regular people are getting it much less on a small subset of people. Until we get better testing data I'm not sure we'll know.

[MannyIsGod]

I think at this point what annoys me is the people following the company line, trying best to quarantine, but basically reflect the poor timing of the administration. The ones who are doing what they're told but also qualifying it with "we're doing what we can, no way we could have been prepared for this" etc
Despite more and more evidence showing 100% we could have acted in late Jan or early February to prevent the severity.
It's annoying af.

https://www.thedailybeast.com/army-warned-in-early-february-that-coronavirus-could-kill-150000-americans

I mean literally every intel and gov/military group was telling the administration this was going to be the real deal and they sat on their asses for an entire MONTH telling joe bob racist alabama fuck and grandma tv watcher that it was fake.

Exactly. This is why there's really no doubt that they have fucked up big time. A month + is a long time. It still would have been an issue but we coudl have saved lives.

[hater]

dont forget the “we are the most prepared country in the world” meme :lmao

muricans were chanting this myth for weeks in Jan and Feb

they even cited some John Holpkins bullshit study

completely false

[hater]

what americans need to realize is EVERYTHING failed

those pinning this on only Trump and his admin are as bad as Trump himself

[Splits]

Ugh oh, Little Jared is on the scene on the old presser.....

:lmao

[hater]

where is Thread today?

hopefully the old bastard is not on a ventilator

[ChumpDumper]

Dude basically all media outlets were posting that this is nothing compared to the regular flu in late January and early February.
What about a week into March?

https://thebulwark.com/app/uploads/2020/04/Image-from-iOS-768x1020.jpg

I await your comment on this.

[Winehole23]

what americans need to realize is EVERYTHING failed

those pinning this on only Trump and his admin are as bad as Trump himselfMayors and governors have done most of the political heavy lifting so far, but in the aggregate they're not noticeably better than Trump, with few notable exceptions.

The US response to COVID-19 is a comprehensive, systemic failure of politics, politicians, economic system and culture.

[TSA]

Coronavirus treatment: Dr. Donald Trump peddles snake oil and false hope
https://www.usatoday.com/story/opinion/todaysdebate/2020/03/21/coronavirus-cure-dr-donald-trump-snake-oil-chloroquine-editorials-debates/2883640001/


Hydroxychloroquine rated 'most effective therapy' by doctors for coronavirus: Global survey
https://m.washingtontimes.com/news/2020/apr/2/hydroxychloroquine-rated-most-effective-therapy-do/

[Reck]

^But cases overall in NY are rising

Big numbers coming out of the rural areas now.

Nassau and Suffolk both reported over a thousand cases. We hadn't seem that before.

[slick'81]

Big numbers coming out of the rural areas now.

Nassau and Suffolk both reported over a thousand cases. We hadn't seem that before.


how you holding up ?

[hater]

Mayors and governors have done most of the political heavy lifting so far, but in the aggregate they're not noticeably better than Trump, with few notable exceptions.

The US response to COVID-19 is a comprehensive, systemic failure of politics, politicians, economic system and culture.

the CDC and entire medical apparatus failed as well

why were there almost no Drs screaming at our unpreparedness?

USA has a 3rd world health system if yo think about it

nobody gave a fuck until now

[Spurtacular]

Coronavirus treatment: Dr. Donald Trump peddles snake oil and false hope
https://www.usatoday.com/story/opinion/todaysdebate/2020/03/21/coronavirus-cure-dr-donald-trump-snake-oil-chloroquine-editorials-debates/2883640001/


Hydroxychloroquine rated 'most effective therapy' by doctors for coronavirus: Global survey
https://m.washingtontimes.com/news/2020/apr/2/hydroxychloroquine-rated-most-effective-therapy-do/

Enemy of the people doing enemy of the people things.

:lmao Chumpettes

[ChumpDumper]

Coronavirus treatment: Dr. Donald Trump peddles snake oil and false hope
https://www.usatoday.com/story/opinion/todaysdebate/2020/03/21/coronavirus-cure-dr-donald-trump-snake-oil-chloroquine-editorials-debates/2883640001/


Hydroxychloroquine rated 'most effective therapy' by doctors for coronavirus: Global survey
https://m.washingtontimes.com/news/2020/apr/2/hydroxychloroquine-rated-most-effective-therapy-do/Even that gets confusing.

The countries with the highest death rates prescribed it the most.

[Reck]

how you holding up ?

Alright I suppose.

What isn't closed entirely are now closing extremely early in the day. The supermarket for example is closing at 5PM.

Went out yesterday to get stuff to get throught the weekend. Cant even order takeout anymore. No one is delivering at night.

[slick'81]

We dont even know if we have immunity after getting infected . People in china are still testing positive after supposedly recovering

[slick'81]

Alright I suppose.

What isn't closed entirely are now closing extremely early in the day. The supermarket for example is closing at 5PM.

Went out yesterday to get stuff to get throught the weekend. Cant even order takeout anymore. No one is delivering at night.


Stay strong,there has to be a light outta this darkness somewhere

[hater]

Coronavirus treatment: Dr. Donald Trump peddles snake oil and false hope
https://www.usatoday.com/story/opinion/todaysdebate/2020/03/21/coronavirus-cure-dr-donald-trump-snake-oil-chloroquine-editorials-debates/2883640001/


Hydroxychloroquine rated 'most effective therapy' by doctors for coronavirus: Global survey
https://m.washingtontimes.com/news/2020/apr/2/hydroxychloroquine-rated-most-effective-therapy-do/

“there is no wonder drug for this” - dear dr facci

many countries including china are touting Cuban drug for its effectiveness. its effective but that doesnt mean this will gonaway

same thing with Dr Trumps recipe :lol

idiots that keep touting it as a wonder drug are in for a rude awakening

[midnightpulp]

I don't mind using Hydroxy as a Hail Mary treatment. Hope it works. BUT WHY THE FUCK IS THIS DRUG BEING POLITICIZED! Rightwing commentators are especially selling it, and not because they give a shit if it saves lives, but because it'll give Dear Leader "a win." I've even seen some rightwing morons claim Fauci is against its use because he's a Dem shill. All the doctor did was rightfully caution that evidence of its efficacy so far is anecdotal. "Hunches" don't work in medicine.

And whether you think Trump erred in promoting the drug is up to you, I guess. I think he should've turned the question about its potential over to the medical professionals. But I won't necessarily rage at Trump for being hopeful, either.

[RandomGuy]

Well do the research on that before you spout off about thousands failing.

Also the oxygen hoses didn't just get up and leave when the contract ended. It's quite likely and even probable that a good portion of those stored units were never even touched just pencil whipped on a sign off sheet.

I don't think I "spouted off about thousands failing". I know some did fail, but have not really offered any commentary beyond noting that.

I think you are entirely correct about the hoses. They may be simply left off of a checklist, or not. No idea what constitutes "maintenance".

Still, faulty equipment is something to be concerned about. Hopefully someone will look into it a bit more closely, so that it doesn't cause anyone harm.

[spurraider21]

opinion articles :lol

[Chris]

TSA Chris

https://www.wbaltv.com/article/man-intentionally-derails-train-near-us-navy-hospital-ship/32011772#

idgaf about your articles or opinions kthxbye


p.s. don't @ me faggot

[LaMarcus Bryant]

If this country ever goes French Revolution on these people I'll personally pay top dollar to watch them give Kushner what he deserves.

[Chris]

opinion articles :lol

wtf right before my post

weird

[midnightpulp]

Speaking of Dear Leader, I've never seen a Cult of Personality around a president like this in all my years. I mean, just :lol or :(

1245197462697959426

This is basically the theme of the replies:

1245315299697664001

Giving a shit about a pampered billionaire who's had everything handed to him on a silver platter his entire life. But oh no, he might be tired! Let's pray for him.

[RandomGuy]

Coronavirus treatment: Dr. Donald Trump peddles snake oil and false hope
https://www.usatoday.com/story/opinion/todaysdebate/2020/03/21/coronavirus-cure-dr-donald-trump-snake-oil-chloroquine-editorials-debates/2883640001/


Hydroxychloroquine rated 'most effective therapy' by doctors for coronavirus: Global survey
https://m.washingtontimes.com/news/2020/apr/2/hydroxychloroquine-rated-most-effective-therapy-do/


37% of those treating COVID-19 patients rated hydroxychloroquine as the “most effective therapy” from a list of 15 options.


Here are fifteen objects in the room I am in:

1. Cell phone
2. Glass
3. Dictionary
4. A small vial of lens cleaner spray
5. Stamps
6. stapler
7. Grocery receipt
8. A book on septic systems
9. a picture with baby pictures
10. A map of missouri
11. a memorial CD for my uncle
12. a coaster
13. a napkin
14. an ancient printer/scanner
15. a stack of index cards.

if 37% of doctors identified the dictionary as the most nutritious thing to eat on this list, does that mean the dictionary is nutritious?

How effective is the treatment?

If you don't know, why is that?

[vy65]

Wait, so Dear Leader didn't discover/invent hydoxychloroquine?

[slick'81]

Wait, so Dear Leader didn't discover/invent hydoxychloroquine?


Fake it until you make it

[vy65]

Speaking of Dear Leader, I've never seen a Cult of Personality around a president like this in all my years. I mean, just :lol or :(

1245197462697959426

This is basically the theme of the replies:

1245315299697664001

Giving a shit about a pampered billionaire who's had everything handed to him on a silver platter his entire life. But oh no, he might be tired! Let's pray for him.

Bizarre to see people glorify a guy who wouldn't piss on them if they were on fire and literally has had a hand in killing tens of thousands of his own cult. It's this bizarre hybrid of redneck bible thumper - kamikazi pilot

[hater]

Bizarre to see people glorify a guy who wouldn't piss on them if they were on fire and literally has had a hand in killing tens of thousands of his own cult. It's this bizarre hybrid of redneck bible thumper - kamikazi pilot

then again ppl glorified Shitlery *ding

[RandomGuy]

Dude basically all media outlets were posting that this is nothing compared to the regular flu in late January and early February. If the Washington Post (not that I think highly of them) is pushing that then there is zero chance of the average American will do something. You have a point but late January and early February is not a reasonable timeline given what was actually being pushed during that time period.

Edit:. I suppose you were talking about lower levels of government. Your expectations of them are also too high.

The federal government, and its intelligence agencies have better information, and more of it, than any reporter.

What "media outlets" were saying is sort of irrelevant to what the government should have been doing, if the government knew, or should have known better.


The inquiry is in its early stages, according to the network, and is “being done in coordination with the Securities and Exchange Commission.” It is centered around North Carolina Sen. Richard Burr, who reportedly sold off stock in the weeks following the senators-only coronavirus briefing on Jan. 24.
https://people.com/politics/justice-department-probe-senators-sell-stocks-coronavirus-briefing/

It was obvious enough to the Senators briefed on it to dump stocks. Seems like someone at the top knew.

Trump should have known. He has access to the best information on the planet for most things.

Either Trump didn't know (negligence) or Trump knew and lied (evil), because Trump was saying "no problem" right up until he couldn't lie about it anymore.

At some point the MSM actual friends of the people started sounding the alarm. And the Fox propaganda enemies of hte people kept telling Trumps lies for him, KILLING PEOPLE.

Is it ok to kill people to protect Trumps prestige?

[spurraider21]

wtf right before my post

weird
that winehole article wasn't an opinion piece. i was referring to the USA Today article TSA was pointing to

[TSA]

https://mobile.twitter.com/ByronYork/status/1245805185324265475
djohn2oo8 will be coming out of hiding and be posting in the political forum shortly :rollin

[ElNono]

Interesting, I missed that. Would love a link if you've got it handy.

Closest I could find:
https://www.upi.com/Health_News/2020/03/23/New-York-launches-new-COVID-19-drug-trials-more-underway-in-China/3681584975924/

I know that before they started with these, the FDA had to explicitly approve both the drug and plasma for clinical trials.

[TSA]

https://twitter.com/peterjhasson/status/1243213491252670466

https://twitter.com/peterjhasson/status/1245755143481671683

https://mobile.twitter.com/ChuckRossDC/status/1245817870120091648

[baseline bum]

where is Thread today?

hopefully the old bastard is not on a ventilator

Didn't Thread have a bet that it wouldn't reach 1000 deaths a day in the US?

[spurraider21]

Didn't Thread (https://www.spurstalk.com/forums/member.php?u=19320) have a bet that it wouldn't reach 1000 deaths a day in the US?
wasnt ELE

[Reck]

https://mobile.twitter.com/ByronYork/status/1245805185324265475
djohn2oo8 (https://www.spurstalk.com/forums/member.php?u=14870) will be coming out of hiding and be posting in the political forum shortly :rollin

I'm praying for good old djohn. I haven't seem him anywhere on the board. Hopefully he didn't catch this thing.

[ElNono]

Both chloroquine phosphate and hydroxychloroquine have extremely good safety profiles when taken as directed. The more serious complications come from long term use or people with serious heart conditions. You can look up the safety data of virtually any medication (even over the counter) and find serious side effects that happen to some small percentage of people. Medicine is not an exact science.

Too much is being made out of that couple that took 16 times the recommended dose and fucked themselves up.

Too much is also being made of the word anecdotal. Dr. Fauci's initial use of that word was in response to a specific question about using the drug as a prophylactic (to prevent infection not treatment). Now people like Chump are running with it cuz Trump.

As a treatment, we have good in vitro evidence on their inhibition of viral attachment & replication and chemically why it does. We have decades of studies on their inhibition of cytokine production, that's why they are used for autoimmune diseases. And we have a number of small imperfect studies of actual clinical use. That's all a bit more than anecdotal I would say.

That's all very hopeful. We'll see what the large scale study shows. It's not going to be a wonder drug though where you give it to people near or already in organ failure and they all magically get better. Those medicines do not exist.

You have to look at this not from the perspective of you and me, but from the perspective of lawyers. When a doctor is in his own practice, he can run the liability risk himself. When he's in a hospital, the hospital can be liable too, and so there's a plethora of risk management going on there, and the legal department almost always gets involved.

As somebody that has worked in the medical industry for a number of years, there's a huge CYA attitude towards everything, and it's also a big factor why things are so expensive, and every doctor orders a lot of tests that might be unnecessary at times.

[ChumpDumper]

https://mobile.twitter.com/ByronYork/status/1245805185324265475
djohn2oo8 will be coming out of hiding and be posting in the political forum shortly :rollinHas Trump done anything wrong before and/or during this crisis?

Yes or no.

[RandomGuy]

Bizarre to see people glorify a guy who wouldn't piss on them if they were on fire and literally has had a hand in killing tens of thousands of his own cult. It's this bizarre hybrid of redneck bible thumper - kamikazi pilot

The cult has been a long time in building. Right wing radio started it, and fox propaganda channel's constant "we are victims, don't trust the other guys" made the truth an enemy a long time ago.

I have been saying for a long time that these people don't want "fair and balanced" they want an echo chamber.

A lot of this is being driven by evangelicals, who tend to distrust science and "others" much more.

I take it you have seen the Goldwater quote?

[vy65]

You have to look at this not from the perspective of you and me, but from the perspective of lawyers. When a doctor is in his own practice, he can run the liability risk himself. When he's in a hospital, the hospital can be liable too, and so there's a plethora of risk management going on there, and the legal department almost always gets involved.

As somebody that has worked in the medical industry for a number of years, there's a huge CYA attitude towards everything, and it's also a big factor why things are so expensive, and every doctor orders a lot of tests that might be unnecessary at times.

Tort reform my friend, tort reform.

[hater]

USA throwing their admirals under the bus

https://twitter.com/phildstewart/status/1245804004732538880?s=20

[ElNono]

Tort reform my friend, tort reform.

It's a double edged sword, tbh. As much as we're trying to minimize a hospital liability in this case, there's also cases where malpractice can be egregious, and if you're on the receiving end, you would want to recoup as much as you can.

I think it makes more sense to potentially do that in specific cases, like crisis.

[Chris]

that winehole article wasn't an opinion piece. i was referring to the USA Today article TSA was pointing to

I didn't say it was. Your choice of words was peculiar considering we posted at the same time.

[spurraider21]

I didn't say it was. Your choice of words was peculiar considering we posted at the same time.
ah gotcha :tu

honestly the bigger surprise was that you actually chose words instead of a tweet

[Chris]

ah gotcha :tu

honestly the bigger surprise was that you actually chose words instead of a tweet

I'm not interested in blather or minutiae. I leave that to the 99.9%.

Carry on Pleb.

[Reck]

30 Deaths from another 1k day death for us. Fuck

[ElNono]

ah gotcha :tu

honestly the bigger surprise was that you actually chose words instead of a tweet

:lol

[MannyIsGod]

30 Deaths from another 1k day death for us. Fuck

Without NY Numbers yet so its safe to say taht we're at 1k+ today. Fucking insane man.

[Winehole23]

idgaf about your articles or opinions kthxbye


p.s. don't @ me faggotI don't consider your preferences binding. It's not like we're friends or something.

[Blake]

I'm not interested in blather or minutiae. I leave that to the 99.9%.

Carry on Pleb.

Because tweets about Kathy Griffin are important

[DarrinS]

30 Deaths from another 1k day death for us. Fuck

This virus is one insidious MF.

[clambake]

https://mobile.twitter.com/ByronYork/status/1245805185324265475
djohn2oo8 will be coming out of hiding and be posting in the political forum shortly :rollin

ok well that was funny lol

[spurraider21]

Without NY Numbers yet so its safe to say taht we're at 1k+ today. Fucking insane man.
?

https://www.worldometers.info/coronavirus/country/us/

319 reported from NY

[Nathan89]

What about a week into March?

https://thebulwark.com/app/uploads/2020/04/Image-from-iOS-768x1020.jpg

I await your comment on this.

I've already said I didn't like that.

[ChumpDumper]

I've already said I didn't like that.Why didn't you like it?

[Nathan89]

30 Deaths from another 1k day death for us. Fuck

There was no reason not to expect that today. There will be more tomorrow.

[slick'81]

There was no reason not to expect that today. There will be more tomorrow.

yea,200,000 plus here we come

[Chris]

https://twitter.com/Breaking911/status/1245827221861871618?s=19

[Chris]

https://twitter.com/DonaldJTrumpJr/status/1245848740159602688?s=19

[TimDunkem]

https://twitter.com/Breaking911/status/1245827221861871618?s=19

He said 3 weeks about a week ago so, that's on time, not a week ahead.

[ElNono]

Nancy

[RandomGuy]

This virus is one insidious MF.

So is the global climate.

Just sayin.

[boutons_deux]

Trash said the virus was another Dem hoax, and rightwingnutjobs are saying it's a plot to take down Trash, left wing media is overhyping the virus to make Trash look bad. etc

[picnroll]

https://twitter.com/DonaldJTrumpJr/status/1245848740159602688?s=19

Looks like Pelosi should have used Burr and Loeffler for her stocks picks, they apparently used better inside info.

[ChumpDumper]

"should outperform"?

[RandomGuy]

There was no reason not to expect that today. There will be more tomorrow.

Republicans that skew older, are also the ones that are taking the fewest precautions, as are their political leaders. Seems like the conservative ideology is going to be costly in terms of lives.

Evangelicals have driven that anti-science engine right off the tracks, and this is what you get.

[MannyIsGod]

?

https://www.worldometers.info/coronavirus/country/us/

319 reported from NY

Most of that is the early date report on what happened overnight. They had over 500 yesterday.

[boutons_deux]

The American South has resisted social distancing measures —
and we’re all going to pay the price


https://www.rawstory.com/wp-content/uploads/2017/09/Tara-Brandua.png

The urban areas in Texas tried to be proactive even as their state government opposed them.

The South, as a whole, did not instruct people to stay at home and the result is that their travel patterns remained normal, or close to normal.

This is going to matter later.


The inconsistencies in policies—and in when they are imposed—may create new problems, even for places that set limits weeks ago.

“Let’s assume that we flatten the curve,

that we push transmission down in the Bay Area and

we walk away with 1 percent immunity,”

said Dr. George Rutherford, a professor of epidemiology at the University of California, San Francisco.

“Then, people visit from regions that have not sheltered in place, and

we have another run of cases.

This is going to happen.”


There’s a tradeoff to self-quarantining.

People don’t get infected with COVID-19,

so people don’t survive the infection and get immunity.

The isolated communities are nearly as vulnerable to a new outbreak as they were before all this began.

https://www.rawstory.com/2020/04/the-american-south-has-resisted-social-distancing-measures-and-were-all-going-to-pay-the-price/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29 (https://www.rawstory.com/2020/04/the-american-south-has-resisted-social-distancing-measures-and-were-all-going-to-pay-the-price/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29)

Of course, if there is a vaccine in the next few months, the communities that flattened the curve can achieve immunity, will have saved lives, while the Confederacy will gain immunity from being infected with cost of 1000s of lives.

[apalisoc_9]

The American South has resisted social distancing measures —
and we’re all going to pay the price


https://www.rawstory.com/wp-content/uploads/2017/09/Tara-Brandua.png

The urban areas in Texas tried to be proactive even as their state government opposed them.

The South, as a whole, did not instruct people to stay at home and the result is that their travel patterns remained normal, or close to normal.

This is going to matter later.


The inconsistencies in policies—and in when they are imposed—may create new problems, even for places that set limits weeks ago.

“Let’s assume that we flatten the curve,

that we push transmission down in the Bay Area and

we walk away with 1 percent immunity,”

said Dr. George Rutherford, a professor of epidemiology at the University of California, San Francisco.

“Then, people visit from regions that have not sheltered in place, and

we have another run of cases.

This is going to happen.”


There’s a tradeoff to self-quarantining.

People don’t get infected with COVID-19,

so people don’t survive the infection and get immunity.

The isolated communities are nearly as vulnerable to a new outbreak as they were before all this began.

https://www.rawstory.com/2020/04/the-american-south-has-resisted-social-distancing-measures-and-were-all-going-to-pay-the-price/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29 (https://www.rawstory.com/2020/04/the-american-south-has-resisted-social-distancing-measures-and-were-all-going-to-pay-the-price/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29)

Of course, if there is a vaccine in the next few months, the communities that flattened the curve can achieve immunity, will have saved lives, while the Confederacy will gain immunity from being infected with cost of 1000s of lives.






Wow. Those are some hideous looking people.

[CosmicCowboy]

Pelosi is about to get hers. She is pushing for hedge funds to be able to access the small business PPP program.

[TimDunkem]

The American South has resisted social distancing measures —
and we’re all going to pay the price


https://www.rawstory.com/wp-content/uploads/2017/09/Tara-Brandua.png

The urban areas in Texas tried to be proactive even as their state government opposed them.

The South, as a whole, did not instruct people to stay at home and the result is that their travel patterns remained normal, or close to normal.

This is going to matter later.


The inconsistencies in policies—and in when they are imposed—may create new problems, even for places that set limits weeks ago.

“Let’s assume that we flatten the curve,

that we push transmission down in the Bay Area and

we walk away with 1 percent immunity,”

said Dr. George Rutherford, a professor of epidemiology at the University of California, San Francisco.

“Then, people visit from regions that have not sheltered in place, and

we have another run of cases.

This is going to happen.”


There’s a tradeoff to self-quarantining.

People don’t get infected with COVID-19,

so people don’t survive the infection and get immunity.

The isolated communities are nearly as vulnerable to a new outbreak as they were before all this began.

https://www.rawstory.com/2020/04/the-american-south-has-resisted-social-distancing-measures-and-were-all-going-to-pay-the-price/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29 (https://www.rawstory.com/2020/04/the-american-south-has-resisted-social-distancing-measures-and-were-all-going-to-pay-the-price/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+TheRawStory+%28The+Raw+Story% 29)

Of course, if there is a vaccine in the next few months, the communities that flattened the curve can achieve immunity, will have saved lives, while the Confederacy will gain immunity from being infected with cost of 1000s of lives.






I could've told you this months ago. Between the overall poor response from most levels of government, to Trump's cult and how they would hang on to every false statement that came out of his mouth, to the fact that most of the South is full of people with pre-existing conditions - one could see this coming a long time ago.

[DarrinS]

https://www.nytimes.com/2020/04/01/opinion/coronavirus-viral-dose.html

[RandomGuy]

I could've told you this months ago. Between the overall poor response from most levels of government, to Trump's cult and how they would hang on to every false statement that came out of his mouth, to the fact that most of the South is full of people with pre-existing conditions - one could see this coming a long time ago.

https://images.dailykos.com/images/781056/original/90442482_10107473068313120_2911233647610691584_o.j pg?1584822814

Guess which state had the Democratic governor... and which had the Republican governor.

[RandomGuy]

I could've told you this months ago. Between the overall poor response from most levels of government, to Trump's cult and how they would hang on to every false statement that came out of his mouth, to the fact that most of the South is full of people with pre-existing conditions - one could see this coming a long time ago.

'We didn't know': Georgia governor blames lockdown delay on ignorance of asymptomatic COVID-19 cases
https://images.dailykos.com/images/781056/original/90442482_10107473068313120_2911233647610691584_o.j pg?1584822814

[RandomGuy]

“Mark my word, if and when these preachers get control of the [Republican] party, and they're sure trying to do so, it's going to be a terrible damn problem. Frankly, these people frighten me. Politics and governing demand compromise. But these Christians believe they are acting in the name of God, so they can't and won't compromise. I know, I've tried to deal with them.”

[SnakeBoy]

https://www.nytimes.com/2020/04/01/opinion/coronavirus-viral-dose.html

Sounds like bs to me

https://www.newscientist.com/article/2238819-does-a-high-viral-load-or-infectious-dose-make-covid-19-worse/

Infectious dose = minimal viral dose required to get infected

After that it's all about viral load, how quickly the virus replicates inside the infected person.

[DarrinS]

Sounds like bs to me

https://www.newscientist.com/article/2238819-does-a-high-viral-load-or-infectious-dose-make-covid-19-worse/

Infectious dose = minimal viral dose required to get infected

After that it's all about viral load, how quickly the virus replicates inside the infected person.


Thanks. Hard to know what to believe, tbh.

[DarrinS]

Shit, my only daily test is to make sure I can smell things. :lol

This thing is so fucked up.

[ChumpDumper]

https://www.nytimes.com/2020/04/01/opinion/coronavirus-viral-dose.htmlMoving around corners and passing people in the store is an awkward dance.

[DAF86]

2015 archive from Italian TV talking about an artificially created virus by the Chinese government with financial support of US government. It's in Italian but you might find images or words that You can relate.

http://www.rai.it/dl/RaiTV/programmi/media/ContentItem-5e3275ba-475c-4cf4-b402-1e27dc47565b.html

[Millennial_Messiah]

https://images.dailykos.com/images/781056/original/90442482_10107473068313120_2911233647610691584_o.j pg?1584822814

Guess which state had the Democratic governor... and which had the Republican governor.
That's so funny because I was in both states on March 13th and in KY from March 9th-March 13th. Kairotic.

[DMC]

I don't think I "spouted off about thousands failing". I know some did fail, but have not really offered any commentary beyond noting that.

I think you are entirely correct about the hoses. They may be simply left off of a checklist, or not. No idea what constitutes "maintenance".

Still, faulty equipment is something to be concerned about. Hopefully someone will look into it a bit more closely, so that it doesn't cause anyone harm.
I meant "you" in general, not you specifically.

Equipment has a failure rate, a mean time between failures, a time to repair and an out of box failure rate. The OEM has to meet specific guidelines to secure a contract to provide these, so if there's any shortcoming as far as parts being missing, that has to be made right by the OEM or the contracted company servicing the units. I would not want to be the manager in charge of that contract, knowing now that many units my team signed off on just a few months prior have missing parts... it points to failure from top down and no real audits.

[DarrinS]

Moving around corners and passing people in the store is an awkward dance.

I hold my breath and walk away quick, tbh.

[pgardn]

https://www.nytimes.com/2020/04/01/opinion/coronavirus-viral-dose.html

This is one of the many variables we need to know more about with this virus.
There is also evidence that some people produce more concentrated loads of virus as well and this changes throughout the process of going from no symptoms to have symptoms. Add that it might be also true that asymptomatic(really mildly symptomatic)and symptomatic people both produce larger more concentrated loads before symptoms are seen. Add in some people produce viruses over a longer time period.

This is is a mess. We will not figure this out in time this round (hopefully there is not another) for it to really help (except to maybe avoid another round in the fall)

This is basic stuff that should go into modeling but can’t with certainty because we just don’t know yet. We can’t even model the big stuff that accurately. (Base it on Italy because they did this and this but China did this so that means... on and on...)

[DMC]

Sounds like bs to me

https://www.newscientist.com/article/2238819-does-a-high-viral-load-or-infectious-dose-make-covid-19-worse/

Infectious dose = minimal viral dose required to get infected

After that it's all about viral load, how quickly the virus replicates inside the infected person.
No no, it's like gamma radiation. A startling metamorphosis occurs in the body chemistry, transforming the carrier into the incredible hulk.

[DarrinS]

This is one of the many variables we need to know more about with this virus.
There is also evidence that some people produce more concentrated loads of virus as well and this changes throughout the process of going from no symptoms to have symptoms. Add that it might be also true that asymptomatic(really mildly symptomatic)and symptomatic people both produce larger more concentrated loads before symptoms are seen. Add in some people produce viruses over a longer time period.

This is is a mess. We will not figure this out in time this round (hopefully there is not another) for it to really help (except to maybe avoid another round in the fall)

This is basic stuff that should go into modeling but can’t with certainty because we just don’t know yet. We can’t even model the big stuff that accurately. (Base it on Italy because they did this and this but China did this so that means... on and on...)



Between the long incubation and asymptomatic spreaders, this is a very shitty virus.

You go from hardly any cases to an explosion of cases in just a few weeks.

I can only hope scientists figure this out quick.

[slick'81]

I hold my breath and walk away quick, tbh.

we need to start wearing masks d

[ChumpDumper]

I hold my breath and walk away quick, tbh.Weird that people seem to be less mindful in bigger stores. If Walmart curbside has enough stuff in stock I'm just not going in to any big boxes the rest of the month.

[pgardn]

Moving around corners and passing people in the store is an awkward dance.

Im even trying to figure out how many bike lengths to stay behind people before I make a sprint to pass them on the trails. Or how to drop back quickly if someone wants to pass me. And this is of course outside. Trying to go at times and bad (hotter or wet) weather when not as many peeps are out.

[SnakeBoy]

Thanks. Hard to know what to believe, tbh.

Yeah, I just noticed the guy used no citations of facts and was a chemist.

If you want to just get an understanding of coronaviruses this is a good read. Hard slog and impossible to understand everything in it without being an expert but still a good read. From 2009...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830095/

Or just read the conclusion. Can't say "we" didn't know...



Perhaps the most important insight made over the past several years is that coronaviruses have and will likely continue to cross between species and cause disease in unrelated hosts. This disease may be mild, like the disease caused by the SARS-like CoV that was transmitted to animal handlers in wet markets in China, but it may be severe, as illustrated by the transmission that triggered the SARS epidemic. Further, SARS-CoV appeared to use an entirely new receptor when it crossed species from bats to palm civets and humans. As part of this transmission to a new species, the virus also needed to evolve strategies to evade the innate immune response of the new hosts. One future goal will be to further delineate how the virus evades the immune response and better understand its interaction with the T and B cell responses, both in the original host (bats), in which disease appears to be mild, and in humans and experimentally infected animals.
...

Finally, no effective treatments exist for any coronavirus infections, including SARS140; vaccines, even for animal coronaviruses, are not effective; and live attenuated vaccines are prone to recombination with circulating coronaviruses. One future goal will be to translate new information about the structure and function of coronavirus proteins into specific anti-virus therapies. Also, development of live, attenuated, safe vaccines that do not recombine in the wild is another goal, made more feasible as more is learned about basic coronavirus biology. Over the past few years, the development of new technologies has simplified the identification of novel coronaviruses; the next major goals will be to understand viral pathogenesis and to design effective coronavirus vaccines and therapies.

[DarrinS]

we need to start wearing masks d

Yes

[DarrinS]

Weird that people seem to be less mindful in bigger stores. If Walmart curbside has enough stuff in stock I'm just not going in to any big boxes the rest of the month.


My wife did one last trip this week. It's curbside from here on out.

[DarrinS]

Yeah, I just noticed the guy used no citations of facts and was a chemist.

If you want to just get an understanding of coronaviruses this is a good read. Hard slog and impossible to understand everything in it without being an expert but still a good read. From 2009...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830095/

Or just read the conclusion. Can't say "we" didn't know...

Fuck, that wasn't very reassuring.

[ChumpDumper]

Im even trying to figure out how many bike lengths to stay behind people before I make a sprint to pass them on the trails. Or how to drop back quickly if someone wants to pass me. And this is of course outside. Trying to go at times and bad (hotter or wet) weather when not as many peeps are out.Luckily I'm in a much less dense part of town. I'd be downright paranoid in the city right now.

[Chris]

https://twitter.com/RealSaavedra/status/1245888742054719488?s=19

[DarrinS]

I still see people cough into their hand all the time and then touch things. This is a major source of transmission.

[DarrinS]

Luckily I'm in a much less dense part of town. I'd be downright paranoid in the city right now.


Same here. There's only between 1-4 people in my zip code that are positive. Might as well multiply that by 10 tho.

[SnakeBoy]

I meant "you" in general, not you specifically.

Equipment has a failure rate, a mean time between failures, a time to repair and an out of box failure rate. The OEM has to meet specific guidelines to secure a contract to provide these, so if there's any shortcoming as far as parts being missing, that has to be made right by the OEM or the contracted company servicing the units. I would not want to be the manager in charge of that contract, knowing now that many units my team signed off on just a few months prior have missing parts... it points to failure from top down and no real audits.

From what I read most of the ventilators reported as faulty and needing repair had dead batteries because they've been sitting unopened in storage for over a decade.

[DAF86]

https://twitter.com/RealSaavedra/status/1245888742054719488?s=19

"Could have"?


2015 archive from Italian TV talking about an artificially created virus by the Chinese government with financial support of US government. It's in Italian but you might find images or words that You can relate.

http://www.rai.it/dl/RaiTV/programmi/media/ContentItem-5e3275ba-475c-4cf4-b402-1e27dc47565b.html

[ChumpDumper]

Same here. There's only between 1-4 people in my zip code that are positive. Might as well multiply that by 10 tho.Yeah, I keep seeing 2 but there's no way that's it.

[SnakeBoy]

Fuck, that wasn't very reassuring.

Well I found it reassuring that very smart people have been trying to figure this shit out for a long time.

Better than the alternative...


https://www.youtube.com/watch?time_continue=10&v=_B7MzBmjaJ8&feature=emb_logo

[Blake]

Moving around corners and passing people in the store is an awkward dance.

I'm finding myself getting pissed off when people get in my 6 foot zone. Sucks it's like this

[DAF86]

https://twitter.com/RealSaavedra/status/1245888742054719488?s=19

lol all those "America fuck yeah" commentators when they find out the US was involved too. :lol

[SnakeBoy]

I'm finding myself getting pissed off when people get in my 6 foot zone. Sucks it's like this

I had a guy at tractor supply who kept standing like 2 feet behind me in line and he had the sniffles. Would have really pissed me off if I wasn't 99% sure I've already had it.

[ChumpDumper]

I'm finding myself getting pissed off when people get in my 6 foot zone. Sucks it's like thisYeah, the bigger the store, the more people act like it's a normal browse and chat scene. Dollar General has been great as they always have something if not what I'm specifically looking for and I'm in and out quickly.

[midnightpulp]

Capitalism bad now.

https://townhall.com/tipsheet/bronsonstocking/2020/04/02/trump-hits-3m-for-selling-masks-to-foreign-governments-amid-coronavirus-pandemic-n2566277

But props to Dear Leader for his second stopped clocked moment during this shitshow. Also, been saying this for years. The profit motive and saving lives is fundamentally incompatible. This 3M situation is an example of that.

[RandomGuy]

Moving around corners and passing people in the store is an awkward dance.

+1

Inheirited a lot of mom's food hoard, but Dad and I still need eggs and stuff once per week. Probably enough canned goods to not have to go to the store at all for a month.

At some point, I have to wonder "is it really worth it to get X"? increasingly... those gravy packets look more and more edible. heh

[ChumpDumper]

Capitalism bad now.

https://townhall.com/tipsheet/bronsonstocking/2020/04/02/trump-hits-3m-for-selling-masks-to-foreign-governments-amid-coronavirus-pandemic-n2566277

But props to Dear Leader for his second stopped clocked moment during this shitshow. Also, been saying this for years. The profit motive and saving lives is fundamentally incompatible. This 3M situation is an example of that.Basically he's doing everything two months late.

[midnightpulp]

1245922703824936961

[Reck]

"Could have"?

Yeah maybe it's time to lay off the crazy conspiracy sites for a while.

:lol This screws China, USA and pretty much everyone else short and long term economically.

[RandomGuy]

Yeah, I keep seeing 2 but there's no way that's it.

Some counties in Texas report zero,while right next door there are a few dozen cases. Zoom in on north texas around lubbock.

Aint' no way we have data on all texas counties.

[midnightpulp]

Basically he's doing everything two months late.

I just find this situation funny because conservatives sure are singing a different tune about capitalism right now. Even Dear Leader, via the defense production act, is behaving socialist. That said, I'm a capitalist, but not a total capitalist. There's some areas where it's just incompatible due to serious conflicts of interests.

[ChumpDumper]

+1

Inheirited a lot of mom's food hoard, but Dad and I still need eggs and stuff once per week. Probably enough canned goods to not have to go to the store at all for a month.

At some point, I have to wonder "is it really worth it to get X"? increasingly... those gravy packets look more and more edible. hehBuilt up about three weeks worth in smaller purchases here and there. One sizable curbside order in a week or so and that's gonna be it for what looks like the peak transmission time here.

[DAF86]

Yeah maybe it's time to lay off the crazy conspiracy sites for a while.

:lol This screws China, USA and pretty much everyone else short and long term economically.

Dude, what conspiracy site? I uploaded a video from RAI. That is the most prestigious Italian network. The only reason I searched for it it was because I saw it on live TV here in Argentina.

X-0a3dFE5bw

[pgardn]

Fuck, that wasn't very reassuring.

Its about coronaviruses involved in disease in general which we must have a look at and fall back on.

But Now we got a new guy on the block.

This below an opinion but it involves more recent studies. On some of these you just have to follow the citations in the article before you find even larger comparison article.

https://www.the-scientist.com/news-opinion/scientists-compare-novel-coronavirus-to-sars-and-mers-viruses-67088

where just one fork leads to...

https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(20)30072-X

And then you realize there are even more citations exponentially increasing and many are from China. Which is to be expected, but peer reviewed and trusted when you get to a series of real studies? not just comparison articles.
Bleh.

Its new. It’s different.

[SnakeBoy]

Basically he's doing everything two months late.

lol Hindsight expert will be a career description by the end of this pandemic

[Blake]

Piece of shit hobby lobby.

1245854732381327360

[RandomGuy]

Yeah, I just noticed the guy used no citations of facts and was a chemist.

If you want to just get an understanding of coronaviruses this is a good read. Hard slog and impossible to understand everything in it without being an expert but still a good read. From 2009...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830095/

Or just read the conclusion. Can't say "we" didn't know...

There is your shutdown challenge. Understand all the technical stuff in there. (bookmarks) Fun weekend project. I got a lot of that stuff, but there is enough vocab to occupy a few days.

[Nathan89]

yea,200,000 plus here we come

Apparently the 100k-200k is modeled only till August and doesn't consider a second wave. So yeah unless these drugs being tested end up working miraculously.

[ChumpDumper]

lol Hindsight expert will be a career description by the end of this pandemicI'm sorry your guy is such a horrible failure when it actually counts.

Gotta be a terrible feeling.

[Nathan89]

Trash said the virus was another Dem hoax, and rightwingnutjobs are saying it's a plot to take down Trash, left wing media is overhyping the virus to make Trash look bad. etc

False.

[DarrinS]

Yeah, the bigger the store, the more people act like it's a normal browse and chat scene. Dollar General has been great as they always have something if not what I'm specifically looking for and I'm in and out quickly.


My local CVS pharmacy is pretty empty. And you can usually find the soap, isopropyl alcohol, etc. that is usually gone at the grocery. But, CVS is pretty expensive. I don't GAF at this point.

[RandomGuy]

Apparently the 100k-200k is modeled only till August and doesn't consider a second wave. So yeah unless these drugs being tested end up working miraculously.

.0066*.6*330,000,000= way more than 200k

Expert modeling keeps inching the average prediction up, currently past 200k.

At this point, if Trump says "less than 200k", the smart money is on more, and even you know it.

[ChumpDumper]

My local CVS pharmacy is pretty empty. And you can usually find the soap, isopropyl alcohol, etc. that is usually gone at the grocery. But, CVS is pretty expensive. I don't GAF at this point.Yeah, the 24-hour CVS stores here haven't cut their hours so that's been great at night.

[Nathan89]

Shit, my only daily test is to make sure I can smell things. :lol

This thing is so fucked up.

:lol